product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Histone H2AX Antibody - BSA Free
catalog :
NB100-638
quantity :
100 ul
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 7h
Choe K, Nicolae C, Constantin D, Imamura Kawasawa Y, Delgado Diaz M, De S, et al. HUWE1 interacts with PCNA to alleviate replication stress. EMBO Rep. 2016;17:874-86 pubmed publisher
Konopka A, Whelan D, Jamali M, Perri E, Shahheydari H, Toth R, et al. Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations. Mol Neurodegener. 2020;15:51 pubmed publisher
Chilewski S, Bhosale D, Dees S, Hutchinson I, Trimble R, Pontiggia L, et al. Development of CAPER peptides for the treatment of triple negative breast cancer. Cell Cycle. 2020;19:432-447 pubmed publisher
Vanzo R, Bartkova J, Merchut Maya J, Hall A, Bouchal J, Dyrskjøt L, et al. Autophagy role(s) in response to oncogenes and DNA replication stress. Cell Death Differ. 2019;: pubmed publisher
Campbell M, Pontiggia L, Russell A, Schwarting R, Camacho J, Jasmin J, et al. CAPER as a therapeutic target for triple negative breast cancer. Oncotarget. 2018;9:30340-30354 pubmed publisher
Pelz L, Purfürst B, Rathjen F. The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice. J Biol Chem. 2017;292:21490-21503 pubmed publisher
Weyemi U, Redon C, Choudhuri R, Aziz T, Maeda D, Boufraqech M, et al. The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition. Nat Commun. 2016;7:10711 pubmed publisher
Sharma V, Khurana S, Kubben N, Abdelmohsen K, Oberdoerffer P, Gorospe M, et al. A BRCA1-interacting lncRNA regulates homologous recombination. EMBO Rep. 2015;16:1520-34 pubmed publisher
Bakhoum S, Kabeche L, Wood M, Laucius C, Qu D, Laughney A, et al. Numerical chromosomal instability mediates susceptibility to radiation treatment. Nat Commun. 2015;6:5990 pubmed publisher
product information
master code :
NB100-638
SKU :
NB100-638
product name :
Histone H2AX Antibody - BSA Free
unit size :
100 ul
description :
The Histone H2AX Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Histone H2AX. This antibody reacts with human,mouse,hamster - cricetulus (chinese hamster). The Histone H2AX Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Knockout Validated.
target :
Histone H2AX
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to the C-terminus of human histone H2AX using the numbering given for Swiss-Prot entry P16104 (GeneID 3014).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Hamster - Cricetulus (Chinese Hamster)
theoretical molecular weight :
15 kDa
gene symbol :
H2AX
Antibody validation :
Biological Validation
accessionNumbers :
P16104
applications :
IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Knockout Validated
USD :
469 USD
alt names :
H2A.X, H2A/X, H2AFX
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.