product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ROCK1 Antibody - BSA Free
catalog :
NB100-624
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 7
Reference
Xia L, Bouamar H, Gu X, Zeballos C, Qin T, Wang B, et al. Gli2 mediates the development of castration‑resistant prostate cancer. Int J Oncol. 2020;57:100-112 pubmed publisher
Mazzone A, Gibbons S, Eisenman S, Strege P, Zheng T, D Amato M, et al. Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins. FASEB J. 2019;33:6632-6642 pubmed publisher
Zhu H, Xia L, Shen Q, Zhao M, Gu X, Bouamar H, et al. Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo. Lab Invest. 2018;98:1384-1396 pubmed publisher
Ebhardt H, Degen S, Tadini V, Schilb A, Johns N, Greig C, et al. Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: a pilot study. J Cachexia Sarcopenia Muscle. 2017;8:567-582 pubmed publisher
Wu M, Ingram L, Tolosa E, Vera R, Li Q, Kim S, et al. Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis. J Biol Chem. 2016;291:25749-25760 pubmed
Jackson D, Smith T, Amarsaikhan N, Han W, Neil M, Boi S, et al. Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells. J Immunol. 2015;195:2908-16 pubmed publisher
Won K, Kim G, Lim S, Sung J, Kim Y, Park Y, et al. Autophagy is related to the hedgehog signaling pathway in human gastric adenocarcinoma: prognostic significance of Beclin-1 and Gli2 expression in human gastric adenocarcinoma. Pathol Res Pract. 2015;211:308-15 pubmed publisher
product information
master code :
NB100-624
SKU :
NB100-624
product name :
ROCK1 Antibody - BSA Free
unit size :
100 ul
description :
The ROCK1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to ROCK1. This antibody reacts with human,mouse. The ROCK1 Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation.
target :
ROCK1
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 1300 and the C-terminus (residue 1354) of human Rho-associated, coiled-coil containing protein kinase 1 using the numbering given in Swiss-Prot entry Q13464 (GeneID 6093).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
specificity :
NB100-624 is specific for human Rho Kinase Beta protein
gene symbol :
ROCK1
accessionNumbers :
Q13464
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation
USD :
459 USD
alt names :
EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.