product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
FOXO3 Antibody
catalog :
NB100-614
quantity :
100 ul
price :
429 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RW105
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:3000; loading ...; fig 2a
Oh H, Paik J. Genetic Ablation of FOXO in Mice to Investigate Its Physiological Role. Methods Mol Biol. 2019;1890:239-248 pubmed publisher
Hornsveld M, Feringa F, Krenning L, van den Berg J, Smits L, Nguyen N, et al. A FOXO-dependent replication checkpoint restricts proliferation of damaged cells. Cell Rep. 2021;34:108675 pubmed publisher
Ludikhuize M, Meerlo M, Gallego M, Xanthakis D, Burgaya Julià M, Nguyen N, et al. Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis. Cell Metab. 2020;32:889-900.e7 pubmed publisher
Dhar S, Zhao D, Lin T, Gu B, Pal K, Wu S, et al. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Mol Cell. 2018;70:825-841.e6 pubmed publisher
Srivastava T, Diba P, Dean J, Banine F, Shaver D, Hagen M, et al. A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors. J Clin Invest. 2018;128:2025-2041 pubmed publisher
Hwang I, Oh H, Santo E, Kim D, Chen J, Bronson R, et al. FOXO protects against age-progressive axonal degeneration. Aging Cell. 2018;17: pubmed publisher
Lin C, Jan M, Kuo J. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. 2015;12:2858-68 pubmed publisher
He M, Zheng B, Zhang Y, Zhang X, Wang C, Yang Z, et al. KLF4 mediates the link between TGF-β1-induced gene transcription and H3 acetylation in vascular smooth muscle cells. FASEB J. 2015;29:4059-70 pubmed publisher
Yi P, Wang Z, Feng Q, Pintilie G, Foulds C, Lanz R, et al. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015;57:1047-1058 pubmed publisher
Byun S, Chang Y, Chung I, Moss S, Kim S. Helicobacter pylori decreases p27 expression through the delta opioid receptor-mediated inhibition of histone acetylation within the p27 promoter. Cancer Lett. 2012;326:96-104 pubmed publisher
product information
brand :
Novus
master code :
NB100-614
SKU :
NB100-614
product name :
FOXO3 Antibody
description :
The FOXO3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to FOXO3. This antibody reacts with human, mouse, porcine. The FOXO3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Knockout Validated, Knockdown Validated.
target :
FOXO3
category :
Primary Antibodies
sizes available :
100 ul
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 625 and the C-terminus (residue 673) of human Forkhead Box O3a using the numbering given in Swiss-Prot entry O43524 (GeneID 2309).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Porcine
specificity :
NB100-614 is specific for human FOXO3a protein
theoretical molecular weight :
71.3 kDa
gene symbol :
FOXO3
accessionNumbers :
O43524
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Knockout Validated, Knockdown Validated
USD :
431
USD 2023 :
429 USD
alt names :
AF6q21, AF6q21 protein, DKFZp781A0677, FKHRL1MGC31925, FKHRL1P2, forkhead box O3, forkhead box protein O3, forkhead homolog (rhabdomyosarcoma) like 1, Forkhead in rhabdomyosarcoma-like 1, forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1, FOXO2, FOXO3Aforkhead box O3A, MGC12739
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.