product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PML Protein Antibody
catalog :
NB100-59787
quantity :
0.1 ml
price :
349 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Adenoviridae, human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
Novus Biologicals product webpage
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; Adenoviridae; fig 3G
Komatsu T, Nagata K, Wodrich H. An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies. J Virol. 2016;90:1657-67 pubmed publisher
Yan H, Wang H, Zhong M, Wu S, Yang L, Li K, et al. PML Suppresses Influenza Virus Replication by Promoting FBXW7 Expression. Virol Sin. 2021;36:1154-1164 pubmed publisher
Lee J, Stone J, Desai P, Kosowicz J, Liu J, Ambinder R. Arsenicals, the Integrated Stress Response, and Epstein-Barr Virus Lytic Gene Expression. Viruses. 2021;13: pubmed publisher
Marks D, Heinen N, Bachmann L, Meermeyer S, Werner M, Gallego L, et al. Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load. Acta Neuropathol Commun. 2021;9:66 pubmed publisher
Karle W, Becker S, Stenzel P, Knosalla C, Siegel G, Baum O, et al. Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries. Clin Sci (Lond). 2021;135:887-905 pubmed publisher
Becker S, Steinemann G, Karle W, Roos K, Liem C, Muralikumar S, et al. Stability of Smyd1 in endothelial cells is controlled by PML-dependent SUMOylation upon cytokine stimulation. Biochem J. 2021;478:217-234 pubmed publisher
Grigore F, Yang H, Hanson N, VanBrocklin M, Sarver A, Robinson J. BRAF inhibition in melanoma is associated with the dysregulation of histone methylation and histone methyltransferases. Neoplasia. 2020;22:376-389 pubmed publisher
Hofmann S, Mai J, Masser S, Groitl P, Herrmann A, Sternsdorf T, et al. ATO (Arsenic Trioxide) Effects on Promyelocytic Leukemia Nuclear Bodies Reveals Antiviral Intervention Capacity. Adv Sci (Weinh). 2020;7:1902130 pubmed publisher
Stubbe M, Mai J, Paulus C, Stubbe H, Berscheminski J, Karimi M, et al. Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers. MBio. 2020;11: pubmed publisher
Chen Y, Ou Yang W, Juang H, Chen C, Chen H, Tsui K, et al. Proteomic characterization of arsenic and cadmium exposure in bladder cells. Rapid Commun Mass Spectrom. 2020;34 Suppl 1:e8578 pubmed publisher
Müncheberg S, Hay R, Ip W, Meyer T, Weis C, Brenke J, et al. E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression. J Virol. 2018;92: pubmed publisher
Li K, Wang F, Cao W, Lv X, Hua F, Cui B, et al. TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence. Cancer Cell. 2017;31:697-710.e7 pubmed publisher
Lang A, Eriksson J, Schink K, Lång E, Blicher P, Połeć A, et al. Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites. Nucleus. 2017;8:404-420 pubmed publisher
Yao K, Wu Y, Chen Q, Zhang Z, Chen X, Zhang Y. The Arginine/Lysine-Rich Element within the DNA-Binding Domain Is Essential for Nuclear Localization and Function of the Intracellular Pathogen Resistance 1. PLoS ONE. 2016;11:e0162832 pubmed publisher
Neumann F, Czech Sioli M, Dobner T, Grundhoff A, Schreiner S, Fischer N. Replication of Merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies. J Gen Virol. 2016;97:2926-2938 pubmed publisher
Bürck C, Mund A, Berscheminski J, Kieweg L, Müncheberg S, Dobner T, et al. KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification. J Virol. 2016;90:930-46 pubmed publisher
Berscheminski J, Brun J, Speiseder T, Wimmer P, Ip W, Terzic M, et al. Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation. Oncogene. 2016;35:3178-89 pubmed publisher
Wimmer P, Berscheminski J, Blanchette P, Groitl P, Branton P, Hay R, et al. PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53. Oncogene. 2016;35:69-82 pubmed publisher
Chen H, Hu J, Chen T, Lin Y, Liu X, Lin M, et al. KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination. Oncogene. 2015;34:5141-51 pubmed publisher
product information
brand :
Novus
master code :
NB100-59787
SKU :
NB100-59787
product name :
PML Protein Antibody
description :
The PML Protein Antibody from NB100-59787 is a nb100-59787 antibody to . This antibody reacts with cancer, zinc finger. The PML Protein Antibody has been validated for the following applications: P29590.
target :
PML Protein
category :
Primary Antibodies
unit sizes :
0.1 ml
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 375 and 425 of promyelocytic leukemia using the numbering given in entry NP_150241.2
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse
gene symbol :
PML
accessionNumbers :
P29590
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting, Proximity Ligation Assay, Knockdown Validated
USD :
349 USD
alt names :
MYLPP8675, promyelocytic leukemia, Promyelocytic leukemia protein, RING finger protein 71, RNF71probable transcription factor PML, TRIM19promyelocytic leukemia, inducer of, tripartite motif protein TRIM19, Tripartite motif-containing protein 19
storage :
Store at 4C. Do not freeze.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.