AKT1 [p Ser473] Antibody (104A282) | Novus Biologicals NB100-56749 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

AKT1 [p Ser473] Antibody (104A282)

catalog :

NB100-56749

quantity :

0.1 mg (also 0.025 mg)

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

104A282

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
western blot; human	Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS ONE. 2011;6:e22641 pubmed publisher
	Tacey A, Millar S, Qaradakhi T, Smith C, Hayes A, Anderson S, et al. Undercarboxylated osteocalcin has no adverse effect on endothelial function in rabbit aorta or human vascular cells. J Cell Physiol. 2020;: pubmed publisher
	Lee J, Wolfe D, Darji S, McBrayer M, Colacurcio D, Kumar A, et al. β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7. J Mol Biol. 2020;432:2633-2650 pubmed publisher
	Wiersma V, van Ziel A, Vazquez Sanchez S, Nölle A, Berenjeno Correa E, Bonaterra Pastra A, et al. Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology. Acta Neuropathol. 2019;138:943-970 pubmed publisher
	Malla S, Krueger B, Wartmann T, Sendler M, Mahajan U, Weiss F, et al. Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice. Cell Mol Life Sci. 2019;: pubmed publisher
	Sun L, Tijsma A, Mirabelli C, Baggen J, Wahedi M, Franco D, et al. Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence. Emerg Microbes Infect. 2019;8:1076-1085 pubmed publisher
	Mishra P, Paital B, Jena S, Swain S, Kumar S, Yadav M, et al. Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. Sci Rep. 2019;9:7408 pubmed publisher
	Zhou X, Liu S, Lin X, Xu L, Mao X, Liu J, et al. Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. Med Sci Monit. 2019;25:836-846 pubmed publisher
	Wilden A, Molina J, Feuerborn M, Boyle D, Lee S. Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition. Biochim Biophys Acta Mol Cell Res. 2018;1865:1356-1367 pubmed publisher
	Truschel S, Clayton D, Beckel J, Yabes J, Yao Y, Wolf Johnston A, et al. Age-related endolysosome dysfunction in the rat urothelium. PLoS ONE. 2018;13:e0198817 pubmed publisher
	Kondo H, Maksimova N, Otomo T, Kato H, Imai A, Asano Y, et al. Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. Hum Mol Genet. 2017;26:173-183 pubmed publisher
	Mareninova O, Sendler M, Malla S, Yakubov I, French S, Tokhtaeva E, et al. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 2015;1:678-694 pubmed
	Gurda B, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, et al. Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII. Mol Ther. 2016;24:206-216 pubmed publisher
	Meads M, Fang B, Mathews L, Gemmer J, Nong L, Rosado Lopez I, et al. Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma. Oncogene. 2016;35:2723-34 pubmed publisher
	Wedel S, Hudak L, Seibel J, Juengel E, Tsaur I, Wiesner C, et al. Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001. Life Sci. 2011;88:418-24 pubmed publisher
	Wedel S, Hudak L, Seibel J, Juengel E, Oppermann E, Haferkamp A, et al. Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer. Prostate. 2011;71:722-35 pubmed publisher
	Elamin M, Shinwari Z, Hendrayani S, Al Hindi H, Al Shail E, Khafaga Y, et al. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells. Mol Carcinog. 2010;49:302-14 pubmed publisher
	Juengel E, Engler J, Natsheh I, Jones J, Mickuckyte A, Hudak L, et al. Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. BMC Cancer. 2009;9:161 pubmed publisher
	Luty W, Rodeberg D, Parness J, Vyas Y. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J Immunol. 2007;179:819-29 pubmed
	Nair A, Shishodia S, Ahn K, Kunnumakkara A, Sethi G, Aggarwal B. Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J Immunol. 2006;177:5612-22 pubmed

product information

brand :

Novus

master code :

NB100-56749

SKU :

NB100-56749

product name :

AKT1 [p Ser473] Antibody (104A282)

description :

The AKT1 [p Ser473] Antibody (104A282) from NB100-56749 is a nb100-56749 antibody to . This antibody reacts with angiogenesis, apoptosis, autophagy, cancer, cellular markers, growth and development, hypoxia, mtor pathway, neuronal cell markers, phospho specific, protein kinase, serine kinases, signal transduction, tyrosine kinases. The AKT1 [p Ser473] Antibody (104A282) has been validated for the following applications: P31749.

target :

AKT1

category :

Primary Antibodies

unit sizes :

0.1 mg (also 0.025 mg)

buffer :

PBS

clonality :

Monoclonal

clone :

104A282

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This AKT1 phospho Ser473 antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 473 of human AKT1.

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human, Mouse, Rat, Rabbit

specificity :

Clone 104A282 detects specifically the Ser473 phosphorylated form of AKT1

theoretical molecular weight :

55.7 kDa

gene symbol :

AKT1

accessionNumbers :

P31749

applications :

Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

USD :

329 USD

alt names :

AKT, AKT serine/threonine kinase 1, AKT1m, CWS6, EC 2.7.11, EC 2.7.11.1, PKB, PKB alpha, PKBMGC99656, PRKBA, Protein kinase B, Protein Kinase B Alpha, Proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, RACPKB-ALPHA, Serine-Threonine Protein Kinase, v-akt murine thymoma viral oncogene homolog 1, V-Akt Murine Thymoma Viral Oncogene-Like Protein 1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage