product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TRAILR1/TNFRSF10A Antibody (32A1380)
catalog :
NB100-56747
quantity :
0.1 mg (also 0.025 mg)
price :
329 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32A1380
reactivity :
human
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 41
Published Application/Species/Sample/DilutionReference
  • western blot; human
Qiu F, Hu M, Tang B, Liu X, Zhuang H, Yang J, et al. Annexin V-TRAIL fusion protein is a more sensitive and potent apoptotic inducer for cancer therapy. Sci Rep. 2013;3:3565 pubmed publisher
  • western blot; human
Park S, Cho D, Andera L, Suh N, Kim I. Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins. Mol Cell Biochem. 2013;383:39-48 pubmed publisher
  • flow cytometry; human
Le Poole I, ElMasri W, Denman C, Kroll T, Bommiasamy H, Lyons Eiben G, et al. Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells. Cancer Immunol Immunother. 2008;57:789-97 pubmed
Chen L, Hao M, Yan J, Sun L, Tai G, Cheng H, et al. Citrus-derived DHCP inhibits mitochondrial complex II to enhance TRAIL sensitivity via ROS-induced DR5 upregulation. J Biol Chem. 2021;296:100515 pubmed publisher
Yu J, Berga S, Zou W, Rajakumar A, Man M, Sidell N, et al. Human Endometrial Stromal Cell Differentiation is Stimulated by PPARβ/δ Activation: New Targets for Infertility?. J Clin Endocrinol Metab. 2020;105: pubmed publisher
Scimeca M, Anemona L, Granaglia A, Bonfiglio R, Urbano N, Toschi N, et al. Plaque calcification is driven by different mechanisms of mineralization associated with specific cardiovascular risk factors. Nutr Metab Cardiovasc Dis. 2019;29:1330-1336 pubmed publisher
Alyessary A, Yap A, Othman S, Rahman M, Al Namnam N, Radzi Z. Is there an optimal initial amount of activation for midpalatal suture expansion? : A histomorphometric and immunohistochemical study in a rabbit model. J Orofac Orthop. 2018;79:169-179 pubmed publisher
Jayash S, Hashim N, Misran M, Baharuddin N. Local application of osteoprotegerin-chitosan gel in critical-sized defects in a rabbit model. Peerj. 2017;5:e3513 pubmed publisher
Xue M, Ge Y, Yu C, Zheng Z, He X, Zhao J. Apoptosis is induced by docosahexaenoic acid in breast cancer cells via death receptor and mitochondria-mediated pathways. Mol Med Rep. 2017;16:978-982 pubmed publisher
Wada S, Kanzaki H, Narimiya T, Nakamura Y. Novel device for application of continuous mechanical tensile strain to mammalian cells. Biol Open. 2017;6:518-524 pubmed publisher
Wu Y, Su W, Wu P, Shen P, Jou I. Degradation of elastic fiber and elevated elastase expression in long head of biceps tendinopathy. J Orthop Res. 2017;35:1919-1926 pubmed publisher
Jayash S, Hashim N, Misran M, Baharuddin N. In vitro evaluation of osteoprotegerin in chitosan for potential bone defect applications. Peerj. 2016;4:e2229 pubmed publisher
Cheng M, Wahafu T, Jiang G, Liu W, Qiao Y, Peng X, et al. A novel open-porous magnesium scaffold with controllable microstructures and properties for bone regeneration. Sci Rep. 2016;6:24134 pubmed publisher
Foster K, Jane E, Premkumar D, Morales A, Pollack I. NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5. Int J Oncol. 2015;47:506-16 pubmed publisher
Di Bartolomeo M, Pietrantonio F, Pellegrinelli A, Martinetti A, Mariani L, Daidone M, et al. Osteopontin, E-cadherin, and β-catenin expression as prognostic biomarkers in patients with radically resected gastric cancer. Gastric Cancer. 2016;19:412-420 pubmed publisher
Magro C, Momtahen S, Hagen J. Osteopontin expression in biopsies of calciphylaxis. Eur J Dermatol. 2015;25:20-5 pubmed publisher
Nguyen T, Min Y, Lee B. Nanoparticle biphasic calcium phosphate loading on gelatin-pectin scaffold for improved bone regeneration. Tissue Eng Part A. 2015;21:1376-87 pubmed publisher
Fujita K, Fukuda M, Fukui H, Horie M, Endoh S, Uchida K, et al. Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression. Nanotoxicology. 2015;9:290-301 pubmed publisher
Goswami R, Millo T, Mishra S, Das M, Kapoor M, Tomar N, et al. Expression of osteogenic molecules in the caudate nucleus and gray matter and their potential relevance for Basal Ganglia calcification in hypoparathyroidism. J Clin Endocrinol Metab. 2014;99:1741-8 pubmed publisher
Nguyen T, Lee B. A combination of biphasic calcium phosphate scaffold with hyaluronic acid-gelatin hydrogel as a new tool for bone regeneration. Tissue Eng Part A. 2014;20:1993-2004 pubmed publisher
Nikodemova M, Small A, Smith S, Mitchell G, Watters J. Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats. Neurobiol Dis. 2014;69:43-53 pubmed publisher
Abdulghani J, Allen J, Dicker D, Liu Y, Goldenberg D, Smith C, et al. Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis. PLoS ONE. 2013;8:e75414 pubmed publisher
Bondarenko A, Angrisani N, Meyer Lindenberg A, Seitz J, Waizy H, Reifenrath J. Magnesium-based bone implants: immunohistochemical analysis of peri-implant osteogenesis by evaluation of osteopontin and osteocalcin expression. J Biomed Mater Res A. 2014;102:1449-57 pubmed publisher
Allen J, Ferrini R, Dicker D, Batzer G, Chen E, Oltean D, et al. Targeting TRAIL death receptor 4 with trivalent DR4 Atrimer complexes. Mol Cancer Ther. 2012;11:2087-95 pubmed publisher
Xu L, Song C, Ni M, Meng F, Xie H, Li G. Cellular retinol-binding protein 1 (CRBP-1) regulates osteogenenesis and adipogenesis of mesenchymal stem cells through inhibiting RXR?-induced ?-catenin degradation. Int J Biochem Cell Biol. 2012;44:612-9 pubmed publisher
Rui Y, Lui P, Rolf C, Wong Y, Lee Y, Chan K. Expression of chondro-osteogenic BMPs in clinical samples of patellar tendinopathy. Knee Surg Sports Traumatol Arthrosc. 2012;20:1409-17 pubmed publisher
Jane E, Premkumar D, Pollack I. Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway. Mol Cancer Ther. 2011;10:198-208 pubmed publisher
Lin Y, Chen S, Yue P, Zou W, Benbrook D, Liu S, et al. CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells. Cancer Res. 2008;68:5335-44 pubmed publisher
Tsurushima H, Yuan X, Dillehay L, Leong K. Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors. Cancer Gene Ther. 2007;14:706-16 pubmed
Lee S, Kim Y, Kim C, Seol S, Kim J, Cho S, et al. E2 of hepatitis C virus inhibits apoptosis. J Immunol. 2005;175:8226-35 pubmed
Kroll T, Bommiasamy H, Boissy R, Hernandez C, Nickoloff B, Mestril R, et al. 4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo. J Invest Dermatol. 2005;124:798-806 pubmed
Ren Y, Wagner K, Knee D, Aza Blanc P, Nasoff M, Deveraux Q. Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle. Mol Biol Cell. 2004;15:5064-74 pubmed
Liu X, Yue P, Khuri F, Sun S. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Res. 2004;64:5078-83 pubmed
Shigeno M, Nakao K, Ichikawa T, Suzuki K, Kawakami A, Abiru S, et al. Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation. Oncogene. 2003;22:1653-62 pubmed
Chen X, Kandasamy K, Srivastava R. Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling. Cancer Res. 2003;63:1059-66 pubmed
Guan B, Yue P, Lotan R, Sun S. Evidence that the human death receptor 4 is regulated by activator protein 1. Oncogene. 2002;21:3121-9 pubmed
Bretz J, Mezosi E, Giordano T, Gauger P, Thompson N, Baker J. Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells. Cell Death Differ. 2002;9:274-86 pubmed
Lu G, Janjic B, Janjic J, Whiteside T, Storkus W, Vujanovic N. Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand. J Immunol. 2002;168:1831-9 pubmed
Kon S, Yokosaki Y, Maeda M, Segawa T, Horikoshi Y, Tsukagoshi H, et al. Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences. J Cell Biochem. 2002;84:420-32 pubmed
Krishnamoorthy B, Darnay B, Aggarwal B, Dinh D, Kouraklis G, Olivero W, et al. Glioma cells deficient in urokinase plaminogen activator receptor expression are susceptible to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis. Clin Cancer Res. 2001;7:4195-201 pubmed
Sridhar S, Ali A, Liang Y, El Etreby M, Lewis R, Kumar M. Differential expression of members of the tumor necrosis factor alpha-related apoptosis-inducing ligand pathway in prostate cancer cells. Cancer Res. 2001;61:7179-83 pubmed
product information
brand :
Novus
master code :
NB100-56747
SKU :
NB100-56747
product name :
TRAILR1/TNFRSF10A Antibody (32A1380)
description :
The TRAILR1/TNFRSF10A Antibody (32A1380) from NB100-56747 is a nb100-56747 antibody to . This antibody reacts with apoptosis, cancer. The TRAILR1/TNFRSF10A Antibody (32A1380) has been validated for the following applications: O00220.
target :
TRAILR1/TNFRSF10A
category :
Primary Antibodies
unit sizes :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Monoclonal
clone :
32A1380
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human
gene symbol :
TNFRSF10A
accessionNumbers :
O00220
applications :
Western Blot, Simple Western, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Cell Surface), Flow (Intracellular), CyTOF-ready
USD :
329 USD
alt names :
APO2, CD261, CD261 antigen, cytotoxic TRAIL receptor, Death receptor 4, DR4, DR4 TRAIL receptor 1, TNF-related apoptosis inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TRAIL-R1, TRAILR-1, TRAILR1MGC9365, tumor necrosis factor receptor superfamily member 10A, tumor necrosis factor receptor superfamily, member 10a
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.