NGFI-B alpha/Nur77/NR4A1 Antibody | Novus Biologicals NB100-56745 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

NGFI-B alpha/Nur77/NR4A1 Antibody

catalog :

NB100-56745

quantity :

0.1 mg (also 0.025 mg)

price :

379 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse; loading ...; fig s5a	Carpenter M, Hu Q, Bond A, Lombroso S, Czarnecki K, Lim C, et al. Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes. Nat Commun. 2020;11:504 pubmed publisher
	Bruno N, Nwachukwu J, Hughes D, Srinivasan S, Hawkins R, Sturgill D, et al. Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting. FASEB J. 2021;35:e21999 pubmed publisher
	Guo H, Golczer G, Wittner B, Langenbucher A, Zachariah M, Dubash T, et al. NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer. Mol Cell. 2021;81:4041-4058.e15 pubmed publisher
	Massman L, Pereckas M, Zwagerman N, Olivier Van Stichelen S. O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells. Endocrinology. 2021;162: pubmed publisher
	Ding R, Sun X, Yi B, Liu W, Kazama K, Xu X, et al. Nur77 Attenuates Inflammasome Activation by Inhibiting Caspase-1 Expression in Pulmonary Vascular Endothelial Cells. Am J Respir Cell Mol Biol. 2021;65:288-299 pubmed publisher
	Su W, Zhou Q, Wang Y, Chishti A, Li Q, Dayal S, et al. Deletion of the Capn1 Gene Results in Alterations in Signaling Pathways Related to Alzheimer's Disease, Protein Quality Control and Synaptic Plasticity in Mouse Brain. Front Genet. 2020;11:334 pubmed publisher
	Mohankumar K, Li X, Sung N, Cho Y, Han S, Safe S. Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis. Endocrinology. 2020;161: pubmed publisher
	Shin J, Lee G, Jeong M, Kim H, Won H, Choi Y, et al. Transcriptional coactivator with PDZ-binding motif suppresses the expression of steroidogenic enzymes by nuclear receptor 4 A1 in Leydig cells. FASEB J. 2020;34:5332-5347 pubmed publisher
	Ho V, Herman Bausier P, Shaw C, Conrad K, Garcia Sherman M, Draghi J, et al. An Amyloid Core Sequence in the Major Candida albicans Adhesin Als1p Mediates Cell-Cell Adhesion. MBio. 2019;10: pubmed publisher
	Giampetruzzi A, Danielson E, Gumina V, Jeon M, Boopathy S, Brown R, et al. Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis. Nat Commun. 2019;10:3827 pubmed publisher
	Li X, Yin X, Hong W, Liu J, Jin F, Wang B, et al. The orphan nuclear receptor NUR77 promotes trophoblast invasion at early pregnancy through paracrine placental growth factor. J Mol Med (Berl). 2019;97:1359-1373 pubmed publisher
	Qin H, Gao F, Wang Y, Huang B, Peng L, Mo B, et al. Nur77 promotes cigarette smoke‑induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin-1. Int J Mol Med. 2019;44:25-36 pubmed publisher
	Almonte Baldonado R, Bravo Nuevo A, Gerald D, Benjamin L, Prendergast G, Laury Kleintop L. RhoB antibody alters retinal vascularization in models of murine retinopathy. J Cell Biochem. 2019;120:9381-9391 pubmed publisher
	Imura T, Kobayashi Y, Suzutani K, Ichikawa Tomikawa N, Chiba H. Differential expression of a stress-regulated gene Nr4a2 characterizes early- and late-born hippocampal granule cells. Hippocampus. 2019;29:539-549 pubmed publisher
	Zhang Y, Federation A, Kim S, O Keefe J, Lun M, Xiang D, et al. Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity. J Clin Invest. 2018;128:4898-4911 pubmed publisher
	Lee J, Mand M, Kao C, Zhou Y, Ryu S, Richards A, et al. ATM directs DNA damage responses and proteostasis via genetically separable pathways. Sci Signal. 2018;11: pubmed publisher
	Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed publisher
	Hedrick E, Lee S, Safe S. The nuclear orphan receptor NR4A1 regulates ?1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists. Mol Carcinog. 2017;56:2066-2075 pubmed publisher
	Péan C, Schiebler M, Tan S, Sharrock J, Kierdorf K, Brown K, et al. Regulation of phagocyte triglyceride by a STAT-ATG2 pathway controls mycobacterial infection. Nat Commun. 2017;8:14642 pubmed publisher
	Nolan K, Kaur J, Isaacs J. Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity. Oncotarget. 2017;8:19323-19341 pubmed publisher
	Diehl W, Lin A, Grubaugh N, Carvalho L, Kim K, Kyawe P, et al. Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic. Cell. 2016;167:1088-1098.e6 pubmed publisher
	Li H, Zhao P, Xu Q, Shan S, Hu C, Qiu Z, et al. The autism-related gene SNRPN regulates cortical and spine development via controlling nuclear receptor Nr4a1. Sci Rep. 2016;6:29878 pubmed publisher
	Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza G. PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia. Oncotarget. 2016;7:6379-97 pubmed publisher
	Butkinaree C, Canuel M, Essalmani R, Poirier S, Benjannet S, Asselin M, et al. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. J Biol Chem. 2015;290:18609-20 pubmed publisher
	Hale R, Brittle A, Fisher K, Monk N, Strutt D. Cellular interpretation of the long-range gradient of Four-jointed activity in the Drosophila wing. elife. 2015;4: pubmed publisher

product information

brand :

Novus

master code :

NB100-56745

SKU :

NB100-56745

product name :

NGFI-B alpha/Nur77/NR4A1 Antibody

description :

The NGFI-B alpha/Nur77/NR4A1 Antibody from Novus Biologicals is a rabbit polyclonal antibody to NGFI-B alpha/Nur77/NR4A1. This antibody reacts with human, mouse. The NGFI-B alpha/Nur77/NR4A1 Antibody has been validated for the following applications: Western Blot, Chromatin Immunoprecipitation, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

target :

NGFI-B alpha/Nur77/NR4A1

category :

Primary Antibodies

sizes available :

0.1 mg (also 0.025 mg)

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Partial synthetic peptide made to an internal portion of the human NGFI-B alpha protein (between amino acids 200-300) [UniProt P22736].

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human, Mouse

gene symbol :

NR4A1

accessionNumbers :

P22736

applications :

Western Blot, Chromatin Immunoprecipitation, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin

USD :

377

USD 2023 :

379 USD

alt names :

Early response protein NAK1, GFRP1ST-59, growth factor-inducible nuclear protein N10, HMRNP10, hormone receptor, MGC9485, N10, NAK1, NAK-1, NGFIB, Nuclear hormone receptor NUR/77, nuclear receptor subfamily 4 group A member 1, nuclear receptor subfamily 4, group A, member 1, NUR77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, steroid receptor TR3, Testicular receptor 3, TR3, TR3 orphan receptor

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage