product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TRAF3IP2 Antibody
catalog :
NB100-56740
quantity :
0.1 mg (also 0.025 mg)
price :
379 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
MC-631
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Sukhanov S, Higashi Y, Yoshida T, Mummidi S, Aroor A, Jeffrey Russell J, et al. The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1β and IL-18 secretion. Cell Signal. 2021;77:109825 pubmed publisher
Das N, Carpenter A, Belenchia A, Aroor A, Noda M, Siebenlist U, et al. Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transition. Cell Signal. 2020;68:109506 pubmed publisher
Kaur S, Abu Shahba A, Paananen R, Hongisto H, Hiidenmaa H, Skottman H, et al. Small non-coding RNA landscape of extracellular vesicles from human stem cells. Sci Rep. 2018;8:15503 pubmed publisher
Das N, Carpenter A, Yoshida T, Kumar S, Gautam S, Mostany R, et al. TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart. J Mol Cell Cardiol. 2018;121:107-123 pubmed publisher
Padilla J, Carpenter A, Das N, Kandikattu H, López Ongil S, Martinez Lemus L, et al. TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells. Am J Physiol Heart Circ Physiol. 2018;314:H52-H64 pubmed publisher
Yariswamy M, Yoshida T, Valente A, Kandikattu H, Sakamuri S, Siddesha J, et al. Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction. J Biol Chem. 2016;291:19425-36 pubmed publisher
Mummidi S, Das N, Carpenter A, Kandikattu H, Krenz M, Siebenlist U, et al. Metformin inhibits aldosterone-induced cardiac fibroblast activation, migration and proliferation in vitro, and reverses aldosterone+salt-induced cardiac fibrosis in vivo. J Mol Cell Cardiol. 2016;98:95-102 pubmed publisher
Sakamuri S, Valente A, Siddesha J, Delafontaine P, Siebenlist U, Gardner J, et al. TRAF3IP2 mediates aldosterone/salt-induced cardiac hypertrophy and fibrosis. Mol Cell Endocrinol. 2016;429:84-92 pubmed publisher
Somanna N, Yariswamy M, Garagliano J, Siebenlist U, Mummidi S, Valente A, et al. Aldosterone-induced cardiomyocyte growth, and fibroblast migration and proliferation are mediated by TRAF3IP2. Cell Signal. 2015;27:1928-38 pubmed publisher
Skottman H. Derivation and characterization of three new human embryonic stem cell lines in Finland. In Vitro Cell Dev Biol Anim. 2010;46:206-9 pubmed publisher
Hakala H, Rajala K, Ojala M, Panula S, Areva S, Kellomäki M, et al. Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines. Tissue Eng Part A. 2009;15:1775-85 pubmed publisher
Matin M, Walsh J, Gokhale P, Draper J, Bahrami A, Morton I, et al. Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells. Stem Cells. 2004;22:659-68 pubmed
Henderson J, Draper J, Baillie H, Fishel S, Thomson J, Moore H, et al. Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens. Stem Cells. 2002;20:329-37 pubmed
Przyborski S. Isolation of human embryonal carcinoma stem cells by immunomagnetic sorting. Stem Cells. 2001;19:500-4 pubmed
product information
brand :
Novus
master code :
NB100-56740
SKU :
NB100-56740
product name :
TRAF3IP2 Antibody
description :
The TRAF3IP2 Antibody from Novus Biologicals is a rabbit polyclonal antibody to TRAF3IP2. This antibody reacts with human, mouse. The TRAF3IP2 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin.
target :
TRAF3IP2
category :
Primary Antibodies
sizes available :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This antibody was developed against a synthetic peptide (QDLPRPLRSREFPQFEP) corresponding to amino acids 225-241 of human TRAF3IP2.
isotype :
IgG
purity :
Protein G purified
species :
Human, Mouse
specificity :
An approx
gene symbol :
TRAF3IP2
accessionNumbers :
NP_679211
applications :
Western Blot, Simple Western, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin
USD :
356
USD 2023 :
379 USD
alt names :
ACT1DKFZP586G0522, adapter protein CIKS, C6orf2, C6orf4chromosome 6 open reading frame 5, C6orf5DKFZp586G0522, C6orf6MGC3581, CIKSchromosome 6 open reading frame 2, Connection to IKK and SAPK/JNK, NFkB-activating protein ACT1, Nuclear factor NF-kappa-B activator 1, TRAF3 interacting protein 2, TRAF3-interacting protein 2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.