product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
D4-GDI/RhoGDI2 Antibody (97A1015) - (cleavage specific)
catalog :
NB100-56725
quantity :
0.1 mg (also 0.025 mg)
price :
329 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
97A1015
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse
Nishtala K, Phong T, Steil L, Sauter M, Salazar M, Kandolf R, et al. Proteomic analyses of age related changes in A.BY/SnJ mouse hearts. Proteome Sci. 2013;11:29 pubmed publisher
  • western blot; mouse
Okamoto M, Koga S, Tatsuka M. Differential regulation of caspase-9 by ionizing radiation- and UV-induced apoptotic pathways in thymic cells. Mutat Res. 2010;688:78-87 pubmed publisher
Korski K, Kubli D, Wang B, Khalafalla F, Monsanto M, Firouzi F, et al. Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells. Stem Cells. 2019;37:555-567 pubmed publisher
Yang A, Herter Sprie G, Zhang H, Lin E, Biancur D, Wang X, et al. Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov. 2018;8:276-287 pubmed publisher
Kohler L, Reed S, Sarraf S, Arteaga D, Newton H, Roy C. Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole. MBio. 2016;7: pubmed publisher
Saito T, Asai K, Sato S, Hayashi M, Adachi A, Sasaki Y, et al. Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis. Autophagy. 2016;12:579-87 pubmed publisher
Campos T, Ziehe J, Palma M, Escobar D, Tapia J, Pincheira R, et al. Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy. Mol Carcinog. 2016;55:220-9 pubmed publisher
Hu L, Zou H, Zhan S, Cao K. Biphasic expression of RhoGDI2 in the progression of breast cancer and its negative relation with lymph node metastasis. Oncol Rep. 2007;17:1383-9 pubmed
Jenkins C, Swiatoniowski A, Power M, Lin T. Pseudomonas aeruginosa-induced human mast cell apoptosis is associated with up-regulation of endogenous Bcl-xS and down-regulation of Bcl-xL. J Immunol. 2006;177:8000-7 pubmed
Wang Z, Zhang X, Shen P, Loggie B, Chang Y, Deuel T. A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling. Proc Natl Acad Sci U S A. 2006;103:9063-8 pubmed
Jenkins C, Swiatoniowski A, Issekutz A, Lin T. Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism. J Biol Chem. 2004;279:37201-7 pubmed
Liu C, Lee C, Hong C, Wei Y. Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis. Ann N Y Acad Sci. 2004;1011:133-45 pubmed
Ko C, Shen S, Chen Y. Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species. Free Radic Biol Med. 2004;36:897-910 pubmed
Chen Y, Shen S, Lin H. Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids. Biochem Pharmacol. 2003;66:1139-50 pubmed
Shen S, Chen Y, Hsu F, Lee W. Differential apoptosis-inducing effect of quercetin and its glycosides in human promyeloleukemic HL-60 cells by alternative activation of the caspase 3 cascade. J Cell Biochem. 2003;89:1044-55 pubmed
Chen Y, Shen S, Lee W, Hsu F, Lin H, Ko C, et al. Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production. Biochem Pharmacol. 2002;64:1713-24 pubmed
Gildea J, Seraj M, Oxford G, Harding M, Hampton G, Moskaluk C, et al. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res. 2002;62:6418-23 pubmed
Sato S, Fujita N, Tsuruo T. Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). Oncogene. 2002;21:1727-38 pubmed
Yamaguchi H, Paranawithana S, Lee M, Huang Z, Bhalla K, Wang H. Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells. Cancer Res. 2002;62:466-71 pubmed
Yamaguchi H, Wang H. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene. 2001;20:7779-86 pubmed
Cuddeback S, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, Wu C, et al. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem. 2001;276:20559-65 pubmed
product information
brand :
Novus
master code :
NB100-56725
SKU :
NB100-56725
product name :
D4-GDI/RhoGDI2 Antibody (97A1015) - (cleavage specific)
description :
The D4-GDI/RhoGDI2 Antibody (97A1015) - (cleavage specific) from NB100-56725 is a nb100-56725 antibody to .
target :
D4-GDI/RhoGDI2
category :
Primary Antibodies
unit sizes :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Monoclonal
clone :
97A1015
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
A synthetic peptide corresponding to the region of the Fas-induced cleavage site of human D4-GDI/RhoGDI2 was used as the immunogen.
isotype :
IgG2b Kappa
purity :
Protein G purified
species :
Human, Mouse
specificity :
In anti-Fas treated Jurkat, an approx
gene symbol :
ARHGDIB
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin, Flow (Intracellular)
USD :
329 USD
alt names :
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta, D4, GDIA2, GDID4, Ly-GDI, LYGDI, RAP1GN1, RhoGDI2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.