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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
IkB-alpha [p Ser32, p Ser36] Antibody (39A1413)
catalog :
NB100-56724
quantity :
0.1 mg (also 0.025 mg)
price :
379 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
39A1413
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, immunoprecipitation
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human
Samanta D, Gilkes D, Chaturvedi P, Xiang L, Semenza G. Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc Natl Acad Sci U S A. 2014;111:E5429-38 pubmed publisher
  • western blot; mouse
Das U, Manna K, Sinha M, Datta S, Das D, Chakraborty A, et al. Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model. PLoS ONE. 2014;9:e97599 pubmed publisher
  • western blot; mouse
Li Q, Guo Y, Tan W, Ou Q, Wu W, Sturza D, et al. Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway. Circulation. 2007;116:1577-84 pubmed
Shahbazi S, Zakerali T. The inhibitory role of benzo-dioxole-piperamide on the phosphorylation process as an NF-Kappa B silencer. Biomed Pharmacother. 2022;145:112471 pubmed publisher
Wen Z, Tang Z, Gu L, Xiang X, Qu Y. Immunomodulatory effect of low molecular-weight seleno-aminopolysaccharide on immunosuppressive mice. Int J Biol Macromol. 2019;123:1278-1288 pubmed publisher
Kanno Y, Maruyama C, Matsuda A, Ishisaki A. uPA-derived peptide, Å6 is involved in the suppression of lipopolysaccaride-promoted inflammatory osteoclastogenesis and the resultant bone loss. Immun Inflamm Dis. 2017;5:289-299 pubmed publisher
Gu L, Wen Z, Xiang X, Ma L, Wang X, Ma J, et al. Immunomodulatory effect of low molecular-weight seleno-aminopolysaccharides in intestinal epithelial cells. Int J Biol Macromol. 2017;99:570-577 pubmed publisher
Huhta H, Helminen O, Kauppila J, Salo T, Porvari K, Saarnio J, et al. The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer. J Histochem Cytochem. 2016;64:470-82 pubmed publisher
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Huhta H, Helminen O, Lehenkari P, Saarnio J, Karttunen T, Kauppila J. Toll-like receptors 1, 2, 4 and 6 in esophageal epithelium, Barrett's esophagus, dysplasia and adenocarcinoma. Oncotarget. 2016;7:23658-67 pubmed publisher
Shakibaei M, Allaway D, Nebrich S, Mobasheri A. Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1?-Induced NF-?B Activation in Canine Articular Chondrocytes. Evid Based Complement Alternat Med. 2012;2012:509383 pubmed publisher
Yang M, Hase H, Legarda Addison D, Varughese L, Seed B, Ting A. B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. J Immunol. 2005;175:2814-24 pubmed
Jazirehi A, Huerta Yepez S, Cheng G, Bonavida B. Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis. Cancer Res. 2005;65:264-76 pubmed
Lotz S, Aga E, Wilde I, van Zandbergen G, Hartung T, Solbach W, et al. Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2. J Leukoc Biol. 2004;75:467-77 pubmed
Ikezoe T, Yang Y, Heber D, Taguchi H, Koeffler H. PC-SPES: a potent inhibitor of nuclear factor-kappa B rescues mice from lipopolysaccharide-induced septic shock. Mol Pharmacol. 2003;64:1521-9 pubmed
Han H, Karabiyikoglu M, Kelly S, Sobel R, Yenari M. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab. 2003;23:589-98 pubmed
product information
brand :
Novus
master code :
NB100-56724
SKU :
NB100-56724
product name :
IkB-alpha [p Ser32, p Ser36] Antibody (39A1413)
description :
The IkB-alpha [p Ser32, p Ser36] Antibody (39A1413) from NB100-56724 is a nb100-56724 antibody to . This antibody reacts with chaperone mediated autophagy (cma), phospho specific. The IkB-alpha [p Ser32, p Ser36] Antibody (39A1413) has been validated for the following applications: P25963.
target :
IkB-alpha
category :
Primary Antibodies
unit sizes :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Monoclonal
clone :
39A1413
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This monoclonal antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IkBa.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human, Mouse, Rat, Porcine, Bovine, Canine
specificity :
IkBa (39A1413 ) [Ser32/Ser36]
gene symbol :
NFKBIA
accessionNumbers :
P25963
applications :
Western Blot, Simple Western, Immunoprecipitation
USD :
379 USD
alt names :
alpha, I-kappa-B-alpha, IkappaBalphaNF-kappa-B inhibitor alpha, IKBAikB-alpha, IkB-alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NFKBI, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.