product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Caspase-3 Antibody (31A893) - BSA Free
catalog :
NB100-56709
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
31A893
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human
Wang W, Chen Y, Hsu J, Leu W, Yu C, Chan S, et al. Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation. Naunyn Schmiedebergs Arch Pharmacol. 2014;387:33-45 pubmed publisher
  • western blot; human
Hsiao C, Li T, Chan Y, Hsin L, Liao C, Lee C, et al. WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers. Biochem Pharmacol. 2008;75:847-56 pubmed
Méndez Callejas G, Torrenegra R, Mu xf1 oz D, Celis C, Roso M, Garzon J, et al. A New Flavanone from Chromolaena tacotana (Klatt) R. M. King and H. Rob, Promotes Apoptosis in Human Breast Cancer Cells by Downregulating Antiapoptotic Proteins. Molecules. 2022;28: pubmed publisher
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, et al. Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis. Immunity. 2020;53:204-216.e10 pubmed publisher
Luo Z, Su R, Wang W, Liang Y, Zeng X, Shereen M, et al. EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production. PLoS Pathog. 2019;15:e1008142 pubmed publisher
Odhams C, Roberts A, Vester S, Duarte C, Beales C, Clarke A, et al. Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. Nat Commun. 2019;10:2164 pubmed publisher
Koupenova M, Corkrey H, Vitseva O, Manni G, Pang C, Clancy L, et al. The role of platelets in mediating a response to human influenza infection. Nat Commun. 2019;10:1780 pubmed publisher
Philion C, Ma D, Ruvinov I, Mansour F, Pignanelli C, Noel M, et al. Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo. Oncotarget. 2017;8:110756-110773 pubmed publisher
Ma D, Gilbert T, Pignanelli C, Tarade D, Noel M, Mansour F, et al. Exploiting mitochondrial and oxidative vulnerabilities with a synthetic analog of pancratistatin in combination with piperlongumine for cancer therapy. FASEB J. 2018;32:417-430 pubmed publisher
Pignanelli C, Ma D, Noel M, Ropat J, Mansour F, Curran C, et al. Selective Targeting of Cancer Cells by Oxidative Vulnerabilities with Novel Curcumin Analogs. Sci Rep. 2017;7:1105 pubmed publisher
Tengroth L, Arebro J, Kumlien Geor n S, Winqvist O, Cardell L. Deprived TLR9 expression in apparently healthy nasal mucosa might trigger polyp-growth in chronic rhinosinusitis patients. PLoS ONE. 2014;9:e105618 pubmed publisher
Priya R, Dhanwani R, Patro I, Rao P, Parida M. Differential regulation of TLR mediated innate immune response of mouse neuronal cells following infection with novel ECSA genotype of Chikungunya virus with and without E1:A226V mutation. Infect Genet Evol. 2013;20:396-406 pubmed publisher
Chauhan S, Singh V, Rai R, Rai M, Rai G. Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation. J Clin Immunol. 2013;33:954-64 pubmed publisher
Lehmann S, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, et al. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci. 2012;15:827-35 pubmed publisher
Schultz C, Golembieski W, King D, Brown S, Brodie C, Rempel S. Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival. Mol Cancer. 2012;11:20 pubmed publisher
Chen J, Chi C, Chen H, Wan C, Yang W, Yang A. TNF-alpha renders human peritoneal mesothelial cells sensitive to anti-Fas antibody-induced apoptosis. Nephrol Dial Transplant. 2003;18:1741-7 pubmed
product information
master code :
NB100-56709
SKU :
NB100-56709
product name :
Caspase-3 Antibody (31A893) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The Caspase-3 Antibody (31A893) - BSA Free from Novus is a mouse monoclonal antibody to Caspase-3. This antibody reacts with human. The Caspase-3 Antibody (31A893) - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
Caspase-3
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
31A893
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This Caspase-3 Antibody (31A893) was developed against recombinant full-length human Caspase-3 protein.
isotype :
IgG
purity :
Protein G purified
species :
Human
theoretical molecular weight :
31.7 kDa
gene symbol :
CASP3
Antibody validation :
Independent Anitbodies
accessionNumbers :
P42574
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
Apopain, apoptosis-related cysteine protease, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.