product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SARS Nucleocapsid Protein Antibody - BSA Free
catalog :
NB100-56683
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
SARS coronavirus
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 19
Reference
Basolo A, Poma A, Macerola E, Bonuccelli D, Proietti A, Salvetti A, et al. Autopsy Study of Testicles in COVID-19: Upregulation of Immune-Related Genes and Downregulation of Testis-Specific Genes. J Clin Endocrinol Metab. 2023;108:950-961 pubmed publisher
Planès R, Pinilla M, Santoni K, Hessel A, Passemar C, Lay K, et al. Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells. Mol Cell. 2022;82:2385-2400.e9 pubmed publisher
Poma A, Proietti A, Macerola E, Bonuccelli D, Conti M, Salvetti A, et al. Suppression of Pituitary Hormone Genes in Subjects Who Died From COVID-19 Independently of Virus Detection in the Gland. J Clin Endocrinol Metab. 2022;107:2243-2253 pubmed publisher
Basolo A, Poma A, Bonuccelli D, Proietti A, Macerola E, Ugolini C, et al. Adipose tissue in COVID-19: detection of SARS-CoV-2 in adipocytes and activation of the interferon-alpha response. J Endocrinol Invest. 2022;45:1021-1029 pubmed publisher
Gerber P, Duncan L, Greenwood E, Marelli S, Naamati A, Teixeira Silva A, et al. A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection. PLoS Pathog. 2022;18:e1010265 pubmed publisher
Bestion E, Zandi K, Belouzard S, Andreani J, Lepidi H, Novello M, et al. GNS561 Exhibits Potent Antiviral Activity against SARS-CoV-2 through Autophagy Inhibition. Viruses. 2022;14: pubmed publisher
Cate D, Bishop J, Hsieh H, Glukhova V, Alonzo L, Hermansky H, et al. Antibody Screening Results for Anti-Nucleocapsid Antibodies Toward the Development of a Lateral Flow Assay to Detect SARS-CoV-2 Nucleocapsid Protein. ACS Omega. 2021;6:25116-25123 pubmed publisher
Poma A, Basolo A, Bonuccelli D, Proietti A, Macerola E, Ugolini C, et al. Activation of Type I and Type II Interferon Signaling in SARS-CoV-2-Positive Thyroid Tissue of Patients Dying from COVID-19. Thyroid. 2021;31:1766-1775 pubmed publisher
Tomchaney M, Contoli M, Mayo J, Baraldo S, Li S, Cabel C, et al. Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease. BMC Pulm Med. 2021;21:275 pubmed publisher
Schaller M, Sharma Y, Dupee Z, Nguyen D, Urueña J, Smolchek R, et al. Ex vivo SARS-CoV-2 infection of human lung reveals heterogeneous host defense and therapeutic responses. JCI Insight. 2021;6: pubmed publisher
Poma A, Bonuccelli D, Giannini R, Macerola E, Vignali P, Ugolini C, et al. COVID-19 autopsy cases: detection of virus in endocrine tissues. J Endocrinol Invest. 2021;: pubmed publisher
Meng B, Kemp S, Papa G, Datir R, Ferreira I, Marelli S, et al. Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7. Cell Rep. 2021;35:109292 pubmed publisher
Chapman A, Tang X, Lee J, Chida A, Mercer K, Wharton R, et al. Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies. Sci Rep. 2021;11:9682 pubmed publisher
Cross R, Prasad A, Borisevich V, Woolsey C, Agans K, Deer D, et al. Use of convalescent serum reduces severity of COVID-19 in nonhuman primates. Cell Rep. 2021;34:108837 pubmed publisher
Rebendenne A, Valadão A, Tauziet M, Maarifi G, Bonaventure B, McKellar J, et al. SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells. J Virol. 2021;: pubmed publisher
Rattanapornsompong K, Ngamkham J, Chavalit T, Jitrapakdee S. Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study Its Metabolic Role in Cancer Research. Methods Mol Biol. 2019;1916:273-288 pubmed publisher
Toledo M, Batista Gonzalez A, Merheb E, Aoun M, Tarabra E, Feng D, et al. Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1. Cell Metab. 2018;28:268-281.e4 pubmed publisher
Li X, Han G, Li X, Kan Q, Fan Z, Li Y, et al. Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells. Oncotarget. 2017;8:46363-46380 pubmed publisher
Seale L, Gilman C, Hashimoto A, Ogawa Wong A, Berry M. Diet-induced obesity in the selenocysteine lyase knockout mouse. Antioxid Redox Signal. 2015;23:761-74 pubmed publisher
product information
master code :
NB100-56683
SKU :
NB100-56683
product name :
SARS Nucleocapsid Protein Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The SARS Nucleocapsid Protein Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SARS Nucleocapsid Protein. This antibody reacts with hamster,human,sars-cov,sars-cov-2,virus - sars-cov-2. The SARS Nucleocapsid Protein Antibody - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry,Simple Western,Dual RNAscope ISH-IHC.
target :
SARS Nucleocapsid Protein
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The antibody was developed by immunizing rabbits with a synthetic peptide corresponding to amino acids 354-370 (NKHIDAYKTFPPTEPKK-C) from the N (SARS Nucleocapsid) for the Human SARS coronavirus (Genbank accession no. YP_009724397.2)
isotype :
IgG
purity :
Protein G purified
species :
Hamster,Human,SARS-CoV,SARS-CoV-2,Virus - SARS-CoV-2
specificity :
The was tested on a human cell line transfected with full-length SARS Nucleocapsid cDNA with a predicted molecular weight of 46 kDa
gene symbol :
N
Antibody validation :
Orthogonal Validation
accessionNumbers :
NP_828858.1, NP_828858.1, P59595
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Simple Western,Dual RNAscope ISH-IHC
USD :
409 USD
alt names :
COVID-19 nucleocapsid protein, N, N protein, N structural protein, NC, Nucleocapsid protein, Nucleoprotein, Protein N, SARS coronavirus N protein, SARS coronavirus nucleocapsid protein, SARS CoV, SARS CoV N protein, SARS CoV nucleocapsid protein, SARS N protein, SARS Nucleoprotein, SARSCoV, SARSCoV N protein, SARSCoV nucleocapsid protein, SARSCOV2 N protein, SARS-COV-2 nucleocapsid protein, SARS-COV-2 Nucleoprotein, Severe acute respiratory syndrome
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.