product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Nogo Antibody - BSA Free
catalog :
NB100-56681
quantity :
0.2 ml (also 0.05 ml)
price :
419 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 32
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s2a
  • western blot; mouse; loading ...; fig 2c
Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, et al. NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. J Biol Chem. 2021;296:100624 pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 1a
Farías G, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, et al. Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron. 2019;102:184-201.e8 pubmed publisher
Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, et al. Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia. Cell Rep. 2024;43:114691 pubmed publisher
Veronese M, Kallabis S, Kaczmarek A, Das A, Robers L, Schumacher S, et al. ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway. Life Sci Alliance. 2024;7: pubmed publisher
Gong K, Zhang Z, Chen S, Zhu X, Wang M, Yang X, et al. 6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice. Acta Pharmacol Sin. 2023;44:2216-2229 pubmed publisher
Li J, Sun Y, Xue C, Yang X, Duan Y, Zhao D, et al. Nogo-B deficiency suppresses white adipogenesis by regulating β-catenin signaling. Life Sci. 2023;321:121571 pubmed publisher
Wang X, Yang Y, Zhao D, Zhang S, Chen Y, Chen Y, et al. Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms. J Biol Chem. 2022;298:101561 pubmed publisher
Yousefi R, Jevdokimenko K, Kluever V, Pacheu Grau D, Fornasiero E. Influence of Subcellular Localization and Functional State on Protein Turnover. Cells. 2021;10: pubmed publisher
Zahavi E, Hummel J, Han Y, Bar C, Stucchi R, Altelaar M, et al. Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers. Dev Cell. 2021;: pubmed publisher
Jurriens D, van Batenburg V, Katrukha E, Kapitein L. Mapping the neuronal cytoskeleton using expansion microscopy. Methods Cell Biol. 2021;161:105-124 pubmed publisher
Petrova V, Pearson C, Ching J, Tribble J, Solano A, Yang Y, et al. Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS. Nat Commun. 2020;11:5614 pubmed publisher
Tadepalle N, Robers L, Veronese M, Zentis P, Babatz F, Brodesser S, et al. Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis. Life Sci Alliance. 2020;3: pubmed publisher
Shrestha N, Liu T, Ji Y, Reinert R, Torres M, Li X, et al. Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling. J Clin Invest. 2020;130:3499-3510 pubmed publisher
Liu N, Cai X, Liu T, Zou J, Wang L, Wang G, et al. Hypoxia-inducible factor-1α mediates the expression of mature β cell-disallowed genes in hypoxia-induced β cell dedifferentiation. Biochem Biophys Res Commun. 2020;523:382-388 pubmed publisher
Gómez Banoy N, Guseh J, Li G, Rubio Navarro A, Chen T, Poirier B, et al. Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans. Nat Med. 2019;25:1739-1747 pubmed publisher
Zhang S, Yu M, Guo F, Yang X, Chen Y, Ma C, et al. Rosiglitazone alleviates intrahepatic cholestasis induced by α-naphthylisothiocyanate in mice: The role of circulating 15-deoxy-Δ12,14 -PGJ2 and Nogo. Br J Pharmacol. 2020;177:1041-1060 pubmed publisher
Kuo T, Damle M, Gonzalez B, Egli D, Lazar M, Accili D. Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction. JCI Insight. 2019;5: pubmed publisher
Chino H, Hatta T, Natsume T, Mizushima N. Intrinsically Disordered Protein TEX264 Mediates ER-phagy. Mol Cell. 2019;74:909-921.e6 pubmed publisher
Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, et al. Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells. Breast Cancer Res. 2018;20:112 pubmed publisher
Tersey S, Levasseur E, Syed F, Farb T, Orr K, Nelson J, et al. Episodic β-cell death and dedifferentiation during diet-induced obesity and dysglycemia in male mice. FASEB J. 2018;:fj201800150RR pubmed publisher
Kawaguchi N, Tashiro K, Taniguchi K, Kawai M, Tanaka K, Okuda J, et al. Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:2600-2609 pubmed publisher
Jin Y, Hu W, Liu T, Rana U, Aguilera Barrantes I, Kong A, et al. Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel. Cancer Lett. 2018;419:233-244 pubmed publisher
Wang N, Wang L, Li Y, Fu S, Xue X, Jia L, et al. Targeting ALDH2 with disulfiram/copper reverses the resistance of cancer cells to microtubule inhibitors. Exp Cell Res. 2018;362:72-82 pubmed publisher
Burke S, Batdorf H, Burk D, Noland R, Eder A, Boulos M, et al. db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet. J Diabetes Res. 2017;2017:8503754 pubmed publisher
Ramzy A, Mojibian M, Kieffer T. Insulin-Deficient Mouse β-Cells Do Not Fully Maturebut Can Be Remedied Through Insulin Replacementby Islet Transplantation. Endocrinology. 2018;159:83-102 pubmed publisher
Li M, Xiao A, Floyd D, Olmez I, Lee J, Godlewski J, et al. CDK4/6 inhibition is more active against the glioblastoma proneural subtype. Oncotarget. 2017;8:55319-55331 pubmed publisher
Ishida E, Kim Muller J, Accili D. Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in db/db Mice. Diabetes. 2017;66:2092-2101 pubmed publisher
Feng A, Xiang Y, Gui L, Kaltsidis G, Feng Q, Lu W. Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes. Diabetologia. 2017;60:1033-1042 pubmed publisher
Kim Muller J, Fan J, Kim Y, Lee S, Ishida E, Blaner W, et al. Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice. Nat Commun. 2016;7:12631 pubmed publisher
Rodriguez Feo J, Gallego Delgado J, Puerto M, Wandosell F, Osende J. Reticulon-4B/Nogo-B acts as a molecular linker between microtubules and actin cytoskeleton in vascular smooth muscle cells. Biochim Biophys Acta. 2016;1863:1985-95 pubmed publisher
Cinti F, Bouchi R, Kim Muller J, Ohmura Y, Sandoval P, Masini M, et al. Evidence of ?-Cell Dedifferentiation in Human Type 2 Diabetes. J Clin Endocrinol Metab. 2016;101:1044-54 pubmed publisher
Dahlhoff M, Fröhlich T, Arnold G, Müller U, Leonhardt H, Zouboulis C, et al. Characterization of the sebocyte lipid droplet proteome reveals novel potential regulators of sebaceous lipogenesis. Exp Cell Res. 2015;332:146-55 pubmed publisher
product information
master code :
NB100-56681
SKU :
NB100-56681
product name :
Nogo Antibody - BSA Free
unit size :
0.2 ml (also 0.05 ml)
description :
The Nogo Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Nogo. This antibody reacts with human,mouse,ovine,rabbit,rat,sheep. The Nogo Antibody - BSA Free has been validated for the following applications: IF/IHC,ELISA,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western.
target :
Nogo
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide to an internal portion of human Nogo A (between amino acids 1-50) [UniProt Q9NQC3].
isotype :
IgG
purity :
Protein G purified
species :
Human,Mouse,Ovine,Rabbit,Rat,Sheep
specificity :
This recognizes Nogo-A (approx
gene symbol :
RTN4
accessionNumbers :
Q9NQC3
applications :
IF/IHC,ELISA,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western
USD :
419 USD
alt names :
ASY, foocen, Human NogoA, KIAA0886, My043 protein, Nbla00271, Nbla10545, neurite growth inhibitor 220, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, NI220/250, Nogo protein, NOGO-A, Nogo-B, Nogo-C, NOGOC, NOGORTN4-B1, NSP, NSP-CL, reticulon 4, reticulon 5, reticulon-4, reticulon-5, RTN4-A, RTN4-B2, RTN4-C, RTN-x
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.