Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) - BSA Free | Novus Biologicals NB100-56603 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) - BSA Free

catalog :

NB100-56603

quantity :

0.1 mg (also 0.025 mg)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

156C135.2

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; human	Chen S, Gulla S, Cai C, Balk S. Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation. J Biol Chem. 2012;287:8571-83 pubmed publisher
immunohistochemistry - paraffin section; mouse	Cai H, Smith D, Memarzadeh S, Lowell C, Cooper J, Witte O. Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proc Natl Acad Sci U S A. 2011;108:6579-84 pubmed publisher
western blot; human	Paliouras M, Diamandis E. An AKT activity threshold regulates androgen-dependent and androgen-independent PSA expression in prostate cancer cell lines. Biol Chem. 2008;389:773-80 pubmed publisher
	Grypari I, Logotheti S, Zolota V, Troncoso P, Efstathiou E, Bravou V, et al. The protein arginine methyltransferases (PRMTs) PRMT1 and CARM1 as candidate epigenetic drivers in prostate cancer progression. Medicine (Baltimore). 2021;100:e27094 pubmed publisher
	McAllister M, McCall P, Dickson A, Underwood M, Andersen D, Holmes E, et al. Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer. Prostate Cancer Prostatic Dis. 2020;: pubmed publisher
	Hellwinkel J, Redzic J, Harland T, Gunaydin D, Anchordoquy T, Graner M. Glioma-derived extracellular vesicles selectively suppress immune responses. Neuro Oncol. 2016;18:497-506 pubmed publisher
	Zellweger T, Stürm S, Rey S, Zlobec I, Gsponer J, Rentsch C, et al. Estrogen receptor ? expression and androgen receptor phosphorylation correlate with a poor clinical outcome in hormone-naive prostate cancer and are elevated in castration-resistant disease. Endocr Relat Cancer. 2013;20:403-13 pubmed publisher
	Kasina S, Macoska J. The CXCL12/CXCR4 axis promotes ligand-independent activation of the androgen receptor. Mol Cell Endocrinol. 2012;351:249-63 pubmed publisher
	Varisli L, Gonen Korkmaz C, Syed H, Bogurcu N, Debelec Butuner B, Erbaykent Tepedelen B, et al. Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells. Mol Cell Endocrinol. 2012;350:107-17 pubmed publisher
	Palazzolo I, Burnett B, Young J, Brenne P, La Spada A, Fischbeck K, et al. Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity. Hum Mol Genet. 2007;16:1593-603 pubmed
	Lin S, Chang D, Ying S. Hyaluronan stimulates transformation of androgen-independent prostate cancer. Carcinogenesis. 2007;28:310-20 pubmed
	Kirkegaard T, Edwards J, Tovey S, McGlynn L, Krishna S, Mukherjee R, et al. Observer variation in immunohistochemical analysis of protein expression, time for a change?. Histopathology. 2006;48:787-94 pubmed
	Agapova O, Malone P, Hernandez M. A neuroactive steroid 5alpha-androstane-3alpha,17beta-diol regulates androgen receptor level in astrocytes. J Neurochem. 2006;98:355-63 pubmed
	Lin H, Hu Y, Yang L, Altuwaijri S, Chen Y, Kang H, et al. Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. J Biol Chem. 2003;278:50902-7 pubmed

product information

master code :

NB100-56603

SKU :

NB100-56603

product name :

Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) - BSA Free from Novus is a mouse monoclonal antibody to Androgen R/NR3C4. This antibody reacts with canine,human,mouse,primate,rat. The Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry.

target :

Androgen R/NR3C4

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

156C135.2

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This antibody was developed against a synthetic peptide corresponding to amino acids 207-221 (GRAREAS*GAPTSSKD) of human androgen receptor, containing the serine 213 phosphorylation site: GenBank Accession No. A39248. Note: S* refers to phosphorylated serine in the peptide sequence.

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Canine,Human,Mouse,Primate,Rat

specificity :

In IGF-1 stimulated LNCaP cells (passage number 38), a ~110 kDa band was observed

gene symbol :

Antibody validation :

Biological Validation

accessionNumbers :

P10275

applications :

IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry

USD :

459 USD

alt names :

AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage