PARP Antibody (194C1439) - Cleaved - BSA Free | Novus Biologicals NB100-56599 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

PARP Antibody (194C1439) - Cleaved - BSA Free

catalog :

NB100-56599

quantity :

0.1 mg (also 0.025 mg)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

194C1439

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 13

Reference
Wang S, Chang C, Huang J, Zeng S, Zhang X, Hung M, et al. Gasdermin C sensitizes tumor cells to PARP inhibitor therapy in cancer models. J Clin Invest. 2024;134: pubmed publisher
Szab xf3 V, Cs xe1 k xe1 ny Papp N, G xf6 r xf6 g M, Mad xe1 csy T, Varga x, Kiss A, et al. Orai1 calcium channel inhibition prevents progression of chronic pancreatitis. JCI Insight. 2023;8: pubmed publisher
Erdogan S, Türkekul K. Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation. J Food Biochem. 2020;44:e13253 pubmed publisher
Traub S, Heilker R. hiPS Cell-Derived Neurons for High-Throughput Screening. Methods Mol Biol. 2019;1994:243-263 pubmed publisher
Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O. Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019;692:217-222 pubmed publisher
Modarai S, Gupta A, Opdenaker L, Kowash R, Masters G, Viswanathan V, et al. The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells. Oncotarget. 2018;9:34658-34669 pubmed publisher
Dou X, Li S, Hu L, Ding L, Ma Y, Ma W, et al. Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease. Exp Mol Med. 2018;50:7 pubmed publisher
Jung Y, Cackowski F, Yumoto K, Decker A, Wang J, Kim J, et al. CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes. Cancer Res. 2018;78:2026-2039 pubmed publisher
Melão A, Spit M, Cardoso B, Barata J. Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity. Haematologica. 2016;101:1368-1379 pubmed
Kamal A, Sreekanth K, Kumar P, Shankaraiah N, Balakishan G, Ramaiah M, et al. Synthesis and potential cytotoxic activity of new phenanthrylphenol-pyrrolobenzodiazepines. Eur J Med Chem. 2010;45:2173-81 pubmed publisher
Ko C, Shen S, Chen Y. Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species. Free Radic Biol Med. 2004;36:897-910 pubmed
Chen Y, Shen S, Lin H. Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids. Biochem Pharmacol. 2003;66:1139-50 pubmed
Chen Y, Shen S, Lee W, Hsu F, Lin H, Ko C, et al. Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production. Biochem Pharmacol. 2002;64:1713-24 pubmed

product information

master code :

NB100-56599

SKU :

NB100-56599

product name :

PARP Antibody (194C1439) - Cleaved - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The PARP Antibody (194C1439) - Cleaved - BSA Free from Novus is a mouse monoclonal antibody to PARP. This antibody reacts with human,mouse,rat (negative). The PARP Antibody (194C1439) - Cleaved - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Flow (Intracellular),Immunocytochemistry/ Immunofluorescence.

target :

PARP

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

194C1439

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This antibody was developed by immunizing mice with a synthetic peptide containing amino acids near 214/215-cleavage site of human PARP.

isotype :

IgG2b Kappa

purity :

Protein G purified

species :

Human,Mouse,Rat (Negative)

specificity :

This monoclonal antibody specifically detects a 89-kDa cleavage fragment containing the catalytic and auto modification domain

gene symbol :

PARP1

Antibody validation :

Biological Validation

applications :

Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Flow (Intracellular),Immunocytochemistry/ Immunofluorescence

USD :

359 USD

alt names :

ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADPRT 1, ADPRTADP-ribosyltransferase NAD(+), cleaved PARP, cleaved PARP 1, cleaved PARP apoptosis, cleaved PARP western blot, cleaved PARP-1, EC 2.4.2, EC 2.4.2.30, NAD(+) ADP-ribosyltransferase 1, PARP apoptosis, PARP-1, PARPADPRT1, poly (ADP-ribose) polymerase 1, poly (ADP-ribose) polymerase family, member 1, poly [ADP-ribose] polymerase 1, poly(ADP-ribose) polymerase, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, Poly[ADP-ribose] synthase 1, PPOLpADPRT-1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage