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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide and BSA Free
catalog :
NB100-56593
quantity :
0.1 mg (also 0.025 mg)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12A668
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 11
Reference
Tanaka T, Kelly M, Takei Y, Yamanouchi D. RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice. J Vasc Surg. 2018;68:48S-59S.e1 pubmed publisher
Hu P, Chu G, Zhu G, Yang H, Luthringer D, Prins G, et al. Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer. PLoS ONE. 2011;6:e28670 pubmed publisher
Shin M, Matsuo K, Tada T, Fukushima H, Furuta H, Ozeki S, et al. The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells. Carcinogenesis. 2011;32:1634-40 pubmed publisher
Parrula C, Zimmerman B, Nadella P, Shu S, Rosol T, Fernandez S, et al. Expression of tumor invasion factors determines systemic engraftment and induction of humoral hypercalcemia in a mouse model of adult T-cell leukemia. Vet Pathol. 2009;46:1003-14 pubmed publisher
Ghoreishi M, Bach P, Obst J, Komba M, Fleet J, Dutz J. Expansion of antigen-specific regulatory T cells with the topical vitamin d analog calcipotriol. J Immunol. 2009;182:6071-8 pubmed publisher
Sandra F, Hendarmin L, Kukita T, Nakao Y, Nakamura N, Nakamura S. Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone. Oral Oncol. 2005;41:637-44 pubmed
Rubin J, Chung L, Fan X, Zhu L, Murphy T, Nanes M, et al. Prostate carcinoma cells that have resided in bone have an upregulated IGF-I axis. Prostate. 2004;58:41-9 pubmed
Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater A, et al. Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. Blood. 2001;98:2784-90 pubmed
Pearse R, Sordillo E, Yaccoby S, Wong B, Liau D, Colman N, et al. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A. 2001;98:11581-6 pubmed
Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, et al. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. J Immunol. 2001;166:3574-9 pubmed
Hsu H, Lacey D, Dunstan C, Solovyev I, Colombero A, Timms E, et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci U S A. 1999;96:3540-5 pubmed
product information
master code :
NB100-56593
SKU :
NB100-56593
product name :
TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide and BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide and BSA Free from Novus is a mouse monoclonal antibody to TRANCE/TNFSF11/RANK L. This antibody reacts with human,mouse,rat. The TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide and BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),CyTOF-ready.
target :
TRANCE/TNFSF11/RANK L
category :
Primary Antibodies
buffer :
Sterile - filtered PBS
clonality :
Monoclonal
clone :
12A668
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse TRANCE was used as immunogen (NP_003692).
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human,Mouse,Rat
theoretical molecular weight :
35 kDa
gene symbol :
TNFSF11
applications :
Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),CyTOF-ready
USD :
469 USD
alt names :
CD254, CD254 antigen, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.