product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TEM8/ANTXR1 Antibody (200C1339(SB20)) - BSA Free
catalog :
NB100-56585
quantity :
0.1 mg (also 0.025 mg)
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
200C1339(SB20)
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
Matsuda K, Ohga N, Hida Y, Muraki C, Tsuchiya K, Kurosu T, et al. Isolated tumor endothelial cells maintain specific character during long-term culture. Biochem Biophys Res Commun. 2010;394:947-54 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human
Hotchkiss K, Basile C, Spring S, Bonuccelli G, Lisanti M, Terman B. TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen. Exp Cell Res. 2005;305:133-44 pubmed
  • western blot; human
Nanda A, Carson Walter E, Seaman S, Barber T, Stampfl J, Singh S, et al. TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI). Cancer Res. 2004;64:817-20 pubmed
Kieffer Y, Hocine H, Gentric G, Pelon F, Bernard C, Bourachot B, et al. Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer. Cancer Discov. 2020;10:1330-1351 pubmed publisher
Towers C, Guarnieri A, Micalizzi D, Harrell J, Gillen A, Kim J, et al. The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p. Nat Commun. 2015;6:10077 pubmed publisher
Adrados I, Larrasa Alonso J, Galarreta A, López Antona I, Menéndez C, Abad M, et al. The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genes. Oncogene. 2016;35:3485-94 pubmed publisher
Nagel S, Meyer C, Kaufmann M, Drexler H, MacLeod R. Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma. Oncotarget. 2015;6:40112-26 pubmed publisher
Kahlert C, Lerbs T, Pecqueux M, Herpel E, Hoffmeister M, Jansen L, et al. Overexpression of SIX1 is an independent prognostic marker in stage I-III colorectal cancer. Int J Cancer. 2015;137:2104-13 pubmed publisher
Werner E, Kowalczyk A, Faundez V. Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton. J Biol Chem. 2006;281:23227-36 pubmed
product information
master code :
NB100-56585
SKU :
NB100-56585
product name :
TEM8/ANTXR1 Antibody (200C1339(SB20)) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TEM8/ANTXR1 Antibody (200C1339(SB20)) - BSA Free from Novus is a mouse monoclonal antibody to TEM8/ANTXR1. This antibody reacts with human. The TEM8/ANTXR1 Antibody (200C1339(SB20)) - BSA Free has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.
target :
TEM8/ANTXR1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
200C1339(SB20)
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This monoclonal antibody was developed by immunizing mice with a synthetic peptide containing amino acids 481-497 (CINFTRVKNNQPAKYPL) of human TEM8.
isotype :
IgG1
purity :
Protein G purified
species :
Human
specificity :
Nanda et al (2004) note a passage dependent loss of TEM8 in HUVEC suggesting that that TEM8 may be a specific marker of the endothelial cell (EC) phenotype which is lost as primary EC's age in culture and de-differentiate
gene symbol :
ANTXR1
accessionNumbers :
Q9H6X2
applications :
Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
399 USD
alt names :
anthrax toxin receptor 1, ATR2310008J16Rik, FLJ10601, FLJ11298, FLJ21776, TEM82810405N18Rik, Tumor endothelial marker 8
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.