This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TLR4 Antibody
catalog :
NB100-56580
quantity :
0.1 mg (also 0.025 mg)
price :
329 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
60.11
reactivity :
human, mouse, rat, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 50
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100; loading ...; fig 3
Alanazi A, Fadda L, Alhusaini A, Ahmad R, Hasan I, Mahmoud A. Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats. Antioxidants (Basel). 2020;9: pubmed publisher
Kim S, Shin M, Lee A, Seo B, Park H, Roh S. Improvement of Inflammation through Antioxidant Pathway of Gardeniae Fructus 50% EtOH Extract (GE) from Acute Reflux Esophagitis Rats. Biomed Res Int. 2020;2020:4826176 pubmed publisher
Cho M, Lee O, Chang E, Lee S, Moon S, Lee J, et al. BIRC5 Expression is Regulated in Uterine Epithelium During the Estrous Cycle. Genes (Basel). 2020;11: pubmed publisher
Ring A, Nguyen C, Smbatyan G, Tripathy D, Yu M, Press M, et al. CBP/β-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel). 2018;10: pubmed publisher
Koh G, Kane A, Lee K, Xu Q, Wu X, Roper J, et al. Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. Int J Cancer. 2018;: pubmed publisher
Fenstermaker R, Figel S, Qiu J, Barone T, Dharma S, Winograd E, et al. Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor Growth In Vivo. Clin Cancer Res. 2018;24:2642-2652 pubmed publisher
Gallagher S, Gunatilake D, Beaumont K, Sharp D, Tiffen J, Heinemann A, et al. HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. Int J Cancer. 2018;142:1926-1937 pubmed publisher
Galbo P, Ciesielski M, Figel S, Maguire O, Qiu J, Wiltsie L, et al. Circulating CD9+/GFAP+/survivin+ exosomes in malignant glioma patients following survivin vaccination. Oncotarget. 2017;8:114722-114735 pubmed publisher
Tsang T, Hsueh Y, Wei E, Lundy D, Cheng B, Chen Y, et al. Subcellular Localization of Survivin Determines Its Function in Cardiomyocytes. Theranostics. 2017;7:4577-4590 pubmed publisher
Perconti G, Maranto C, Romancino D, Rubino P, Feo S, Bongiovanni A, et al. Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface. Sci Rep. 2017;7:3841 pubmed publisher
Bae I, Kim C, Kim J, Cheong J, Ryu J, Han M. Correlation of survivin and B-cell lymphoma 2 expression with pathological malignancy and anti-apoptotic properties of glial cell tumors. Biomed Rep. 2017;6:396-400 pubmed publisher
Compare D, Rocco A, Coccoli P, Angrisani D, Sgamato C, Iovine B, et al. Lactobacillus casei DG and its postbiotic reduce the inflammatory mucosal response: an ex-vivo organ culture model of post-infectious irritable bowel syndrome. BMC Gastroenterol. 2017;17:53 pubmed publisher
Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed publisher
Deiuliis J, Syed R, Duggineni D, Rutsky J, Rengasamy P, Zhang J, et al. Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages. PLoS ONE. 2016;11:e0165962 pubmed publisher
Oyama J, Shiraki A, Nishikido T, Maeda T, Komoda H, Shimizu T, et al. EGCG, a green tea catechin, attenuates the progression of heart failure induced by the heart/muscle-specific deletion of MnSOD in mice. J Cardiol. 2017;69:417-427 pubmed publisher
Merkowsky K, Sethi R, Gill J, Singh B. Fipronil induces lung inflammation in vivo and cell death in vitro. J Occup Med Toxicol. 2016;11:10 pubmed publisher
Pahwa R, Devaraj S, Jialal I. The effect of the accessory proteins, soluble CD14 and lipopolysaccharide-binding protein on Toll-like receptor 4 activity in human monocytes and adipocytes. Int J Obes (Lond). 2016;40:907-11 pubmed publisher
Riehl T, Santhanam S, Foster L, Ciorba M, Stenson W. CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice. Am J Physiol Gastrointest Liver Physiol. 2015;309:G874-87 pubmed publisher
Schöneberger H, Weiss A, Brill B, Delis N, Borghouts C, Groner B. The integration of a Stat3 specific peptide aptamer into the thioredoxin scaffold protein strongly enhances its inhibitory potency. Horm Mol Biol Clin Investig. 2011;5:1-9 pubmed publisher
Asuncion Valenzuela M, Castro I, Gonda A, Diaz Osterman C, Jutzy J, Aspe J, et al. Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase. Onco Targets Ther. 2015;8:495-507 pubmed publisher
Kusner L, Ciesielski M, Marx A, Kaminski H, Fenstermaker R. Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. PLoS ONE. 2014;9:e102231 pubmed publisher
Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed publisher
Rho J, Lampe P. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. J Proteome Res. 2013;12:2311-20 pubmed publisher
Khan S, Jutzy J, Valenzuela M, Turay D, Aspe J, Ashok A, et al. Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer. PLoS ONE. 2012;7:e46737 pubmed publisher
Hoel A, Yu P, Nguyen K, Sui X, Plescia J, Altieri D, et al. Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo. Am J Pathol. 2012;181:1151-7 pubmed publisher
de Souza H, West G, Rebert N, de la Motte C, Drazba J, Fiocchi C. Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. Gastroenterology. 2012;143:1017-26.e9 pubmed publisher
Zhang H, Wang Y, Liu C, Zhang L, Xia Q, Zhang Y, et al. DNA and adenovirus tumor vaccine expressing truncated survivin generates specific immune responses and anti-tumor effects in a murine melanoma model. Cancer Immunol Immunother. 2012;61:1857-67 pubmed
Lopergolo A, Tavecchio M, Lisanti S, Ghosh J, Dohi T, Faversani A, et al. Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer. Cancer Res. 2012;72:3251-9 pubmed publisher
Keerthivasan G, Liu H, Gump J, Dowdy S, Wickrema A, Crispino J. A novel role for survivin in erythroblast enucleation. Haematologica. 2012;97:1471-9 pubmed publisher
Sakao K, Desineni S, Hahm E, Singh S. Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo. Prostate. 2012;72:1104-16 pubmed publisher
Femia A, Salvianti F, Luceri C, Dolara P, Salvadori M, Pinzani P, et al. Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis. Int J Cancer. 2012;131:529-36 pubmed publisher
Lechler P, Balakrishnan S, Schaumburger J, Grassel S, Baier C, Grifka J, et al. The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC Musculoskelet Disord. 2011;12:150 pubmed publisher
Lechler P, Schaumburger J, Köck F, Balakrishnan S, Doukas S, Prantl L, et al. The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells. Calcif Tissue Int. 2011;89:211-20 pubmed publisher
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, et al. The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer. 2011;11:120 pubmed publisher
Knauer S, Heinrich U, Bier C, Habtemichael N, Docter D, Helling K, et al. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death Dis. 2010;1:e51 pubmed publisher
Habtemichael N, W nsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, et al. Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin. Gene. 2010;469:9-17 pubmed publisher
Habtemichael N, Heinrich U, Knauer S, Schmidtmann I, Bier C, Docter D, et al. Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. Mol Cell Neurosci. 2010;45:297-305 pubmed publisher
Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen T, et al. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res. 2008;68:3724-32 pubmed publisher
Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, et al. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation. 2008;117:1583-93 pubmed publisher
Hino R, Uozaki H, Inoue Y, Shintani Y, Ushiku T, Sakatani T, et al. Survival advantage of EBV-associated gastric carcinoma: survivin up-regulation by viral latent membrane protein 2A. Cancer Res. 2008;68:1427-35 pubmed publisher
Brocardo M, Lei Y, Tighe A, Taylor S, Mok M, Henderson B. Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival. J Biol Chem. 2008;283:5950-9 pubmed
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, et al. The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. Am J Pathol. 2007;171:1483-98 pubmed
Ryan B, O Donovan N, Browne B, O SHEA C, Crown J, Hill A, et al. Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer. Br J Cancer. 2005;92:120-4 pubmed
Ansell S, Arendt B, Grote D, Jelinek D, Novak A, Wellik L, et al. Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma. Leukemia. 2004;18:616-23 pubmed
Koyama S. Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci. 2003;48:2290-300 pubmed
Ku J, Kwak C, Lee H, Park H, Lee E, Lee S. Expression of survivin, a novel inhibitor of apoptosis, in superficial transitional cell carcinoma of the bladder. J Urol. 2004;171:631-5 pubmed
Xu Z, Zhao R, Ding T, Tran T, Zhang W, Pandolfi P, et al. Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression. J Biol Chem. 2004;279:1838-44 pubmed
Allen S, Florell S, Hanks A, Alexander A, Diedrich M, Altieri D, et al. Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. Cancer Res. 2003;63:567-72 pubmed
Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
Zhu L, Fukuda S, Cordis G, Das D, Maulik N. Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. FEBS Lett. 2001;508:369-74 pubmed
product information
brand :
Novus
master code :
NB100-56580
SKU :
NB100-56580-0.1mg
product name :
TLR4 Antibody
description :
The TLR4 Antibody from Novus Biologicals is a rabbit polyclonal antibody to TLR4. This antibody reacts with human, mouse, rat, rhesus macaque. The TLR4 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
target :
TLR4
category :
Primary Antibodies
unit size :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This TLR4 antibody was developed against a sythetic peptide corresponding to amino acids in a range between 30-80 of mouse TLR4.
isotype :
IgG
purity :
Protein G purified
species :
Human, Mouse, Rat, Rhesus Macaque
theoretical molecular weight :
95.7 kDa
gene symbol :
TLR4
catalog number base :
NB100-56580
accessionNumbers :
O00206
applications :
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
2020 USD :
329
2021 USD :
329 USD
alt names :
ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.