product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TLR1 Antibody - BSA Free
catalog :
NB100-56563
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
5B1288
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, dot blot
more info or order :
citations: 33
Reference
Li Y, Chen X, Jin R, Chen L, Dang M, Cao H, et al. Injectable hydrogel with MSNs/microRNA-21-5p delivery enables both immunomodification and enhanced angiogenesis for myocardial infarction therapy in pigs. Sci Adv. 2021;7: pubmed publisher
Shang L, Deng D, Roffel S, Gibbs S. Differential influence of Streptococcus mitis on host response to metals in reconstructed human skin and oral mucosa. Contact Dermatitis. 2020;83:347-360 pubmed publisher
Ng K, Chan L, Chai S, Tong M, Guan X, Lee N, et al. TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma. Cancer Res. 2017;77:4602-4612 pubmed publisher
Huhta H, Helminen O, Kauppila J, Salo T, Porvari K, Saarnio J, et al. The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer. J Histochem Cytochem. 2016;64:470-82 pubmed publisher
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Huhta H, Helminen O, Lehenkari P, Saarnio J, Karttunen T, Kauppila J. Toll-like receptors 1, 2, 4 and 6 in esophageal epithelium, Barrett's esophagus, dysplasia and adenocarcinoma. Oncotarget. 2016;7:23658-67 pubmed publisher
Venkatanarayan A, Raulji P, Norton W, Chakravarti D, Coarfa C, Su X, et al. IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo. Nature. 2015;517:626-30 pubmed publisher
Lu H, Yan C, Quan X, Yang X, Zhang J, Bian Y, et al. CK2 phosphorylates and inhibits TAp73 tumor suppressor function to promote expression of cancer stem cell genes and phenotype in head and neck cancer. Neoplasia. 2014;16:789-800 pubmed publisher
Guerrieri F, Piconese S, Lacoste C, Schinzari V, Testoni B, Valogne Y, et al. The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells. Cell Death Dis. 2013;4:e807 pubmed publisher
Du W, Jiang P, Mancuso A, Stonestrom A, Brewer M, Minn A, et al. TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nat Cell Biol. 2013;15:991-1000 pubmed publisher
King K, Reddi D, Ponnamperuma R, Gerdes M, Weinberg W. Dysregulated ?Np63? negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding. Mol Carcinog. 2014;53:698-710 pubmed publisher
Niemantsverdriet M, Nagle P, Chiu R, Langendijk J, Kampinga H, Coppes R. ?Np73 enhances promoter activity of TGF-? induced genes. PLoS ONE. 2012;7:e50815 pubmed publisher
Leonard M, Kommagani R, Payal V, Mayo L, Shamma H, Kadakia M. ?Np63? regulates keratinocyte proliferation by controlling PTEN expression and localization. Cell Death Differ. 2011;18:1924-33 pubmed publisher
Rosenbluth J, Johnson K, Tang L, Triplett T, Pietenpol J. Evaluation of p63 and p73 antibodies for cross-reactivity. Cell Cycle. 2009;8:3702-6 pubmed
Lin Y, Sengupta S, Gurdziel K, Bell G, Jacks T, Flores E. p63 and p73 transcriptionally regulate genes involved in DNA repair. PLoS Genet. 2009;5:e1000680 pubmed publisher
Kommagani R, Whitlatch A, Leonard M, Kadakia M. p73 is essential for vitamin D-mediated osteoblastic differentiation. Cell Death Differ. 2010;17:398-407 pubmed publisher
Rosenbluth J, Mays D, Pino M, Tang L, Pietenpol J. A gene signature-based approach identifies mTOR as a regulator of p73. Mol Cell Biol. 2008;28:5951-64 pubmed publisher
Jones E, Dickman M, Whitmarsh A. Regulation of p73-mediated apoptosis by c-Jun N-terminal kinase. Biochem J. 2007;405:617-23 pubmed
Limesand K, Schwertfeger K, Anderson S. MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Mol Cell Biol. 2006;26:8840-56 pubmed
Belloni L, Moretti F, Merlo P, Damalas A, Costanzo A, Blandino G, et al. DNp73alpha protects myogenic cells from apoptosis. Oncogene. 2006;25:3606-12 pubmed
Thottassery J, Westbrook L, Someya H, Parker W. c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells. Mol Cancer Ther. 2006;5:400-10 pubmed
Lunghi P, Costanzo A, Salvatore L, Noguera N, Mazzera L, Tabilio A, et al. MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis. Blood. 2006;107:4549-53 pubmed
Accardi R, Dong W, Smet A, Cui R, Hautefeuille A, Gabet A, et al. Skin human papillomavirus type 38 alters p53 functions by accumulation of deltaNp73. EMBO Rep. 2006;7:334-40 pubmed
Kulesz Martin M, Lagowski J, Fei S, Pelz C, Sears R, Powell M, et al. Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles. J Investig Dermatol Symp Proc. 2005;10:142-52 pubmed
Tomasini R, Seux M, Nowak J, Bontemps C, Carrier A, Dagorn J, et al. TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity. Oncogene. 2005;24:8093-104 pubmed
Merlo P, Fulco M, Costanzo A, Mangiacasale R, Strano S, Blandino G, et al. A role of p73 in mitotic exit. J Biol Chem. 2005;280:30354-60 pubmed
Sayan A, Paradisi A, Vojtesek B, Knight R, Melino G, Candi E. New antibodies recognizing p73: comparison with commercial antibodies. Biochem Biophys Res Commun. 2005;330:186-93 pubmed
Papoutsaki M, Lanza M, Marinari B, Nistico S, Moretti F, Levrero M, et al. The p73 gene is an anti-tumoral target of the RARbeta/gamma-selective retinoid tazarotene. J Invest Dermatol. 2004;123:1162-8 pubmed
Lunghi P, Costanzo A, Levrero M, Bonati A. Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells. Blood. 2004;104:519-25 pubmed
Tullo A, Mastropasqua G, Bourdon J, Centonze P, Gostissa M, Costanzo A, et al. Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target. Oncogene. 2003;22:8738-48 pubmed
Fulco M, Costanzo A, Merlo P, Mangiacasale R, Strano S, Blandino G, et al. p73 is regulated by phosphorylation at the G2/M transition. J Biol Chem. 2003;278:49196-202 pubmed
Vella V, Zhu J, Frasca F, Li C, Vigneri P, Vigneri R, et al. Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function. J Biol Chem. 2003;278:25151-7 pubmed
Costanzo A, Merlo P, Pediconi N, Fulco M, Sartorelli V, Cole P, et al. DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. Mol Cell. 2002;9:175-86 pubmed
product information
master code :
NB100-56563
SKU :
NB100-56563
product name :
TLR1 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TLR1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TLR1. This antibody reacts with human,mouse,rat. The TLR1 Antibody - BSA Free has been validated for the following applications: Cytometric Bead Assay Standard,Flow Cytometry Control,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Dot Blot,Flow (Cell Surface),Flow (Intracellular).
target :
TLR1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This antibody was developed against a KLH-conjugated synthetic peptide corresponding to a sequence within amino acids 400-450 of human TLR1.
isotype :
IgG
purity :
Protein G purified
species :
Human,Mouse,Rat
gene symbol :
TLR1
Antibody validation :
Orthogonal Validation
accessionNumbers :
NP_003254
applications :
Cytometric Bead Assay Standard,Flow Cytometry Control,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Dot Blot,Flow (Cell Surface),Flow (Intracellular)
USD :
409 USD
alt names :
CD281, CD281 antigen, DKFZp547I0610, DKFZp564I0682, KIAA0012MGC126311, MGC104956, MGC126312, rsc786, TIL, TIL. LPRS5, Toll/interleukin-1 receptor-like protein, toll-like receptor 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.