TLR4 Antibody (MTS510) | Novus Biologicals NB100-56560 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TLR4 Antibody (MTS510)

catalog :

NB100-56560

quantity :

0.1 mg (also 0.025 mg)

price :

239 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MTS510

reactivity :

human, mouse

application :

immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Novus Biologicals product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse	Ma C, Shi G, Shi C, Kao Y, Lin S, Wu H. Monocytic thrombomodulin triggers LPS- and gram-negative bacteria-induced inflammatory response. J Immunol. 2012;188:6328-37 pubmed publisher
flow cytometry; mouse	Macedo G, Magnani D, Carvalho N, Bruna Romero O, Gazzinelli R, Oliveira S. Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. J Immunol. 2008;180:1080-7 pubmed
	Mahish C, De S, Chatterjee S, Ghosh S, Keshry S, Mukherjee T, et al. TLR4 is one of the receptors for Chikungunya virus envelope protein E2 and regulates virus induced pro-inflammatory responses in host macrophages. Front Immunol. 2023;14:1139808 pubmed publisher
	Ma S, Xu X, Jones R, Delecluse H, Zumwalde N, Sharma A, et al. PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model. PLoS Pathog. 2016;12:e1005642 pubmed publisher
	Whitehurst C, Li G, Montgomery S, Montgomery N, Su L, Pagano J. Knockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice. MBio. 2015;6:e01574-15 pubmed publisher
	Kim S, Lowe E, Dixit D, Youn C, Kim I, Jung J, et al. Cocaine-mediated impact on HIV infection in humanized BLT mice. Sci Rep. 2015;5:10010 pubmed publisher
	Amelio I, Inoue S, Markert E, Levine A, Knight R, Mak T, et al. TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation. Proc Natl Acad Sci U S A. 2015;112:226-31 pubmed publisher
	Ma S, Xu X, Plowshay J, Ranheim E, Burlingham W, Jensen J, et al. LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis. J Clin Invest. 2015;125:304-15 pubmed publisher
	Gill T, Levine A. Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. J Biol Chem. 2013;288:26246-55 pubmed publisher
	Tsai C, Lin C, Tsai H, Chen C, Li W, Yu H, et al. The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling. J Biol Chem. 2013;288:17689-97 pubmed publisher
	Kim M, Shu Y, Carsillo T, Zhang J, Yu L, Peterson C, et al. hsp70 and a novel axis of type I interferon-dependent antiviral immunity in the measles virus-infected brain. J Virol. 2013;87:998-1009 pubmed publisher
	Ma S, Yu X, Mertz J, Gumperz J, Reinheim E, Zhou Y, et al. An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model. J Virol. 2012;86:7976-87 pubmed publisher
	Bruscia E, Zhang P, Satoh A, Caputo C, Medzhitov R, Shenoy A, et al. Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol. 2011;186:6990-8 pubmed publisher
	Park H, Hong J, Kwon H, Kim Y, Lee K, Kim J, et al. TLR4-mediated activation of mouse macrophages by Korean mistletoe lectin-C (KML-C). Biochem Biophys Res Commun. 2010;396:721-5 pubmed publisher
	Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M. Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells. Int Immunol. 2010;22:271-80 pubmed publisher
	Corbucci C, Cenci E, Skrzypek F, Gabrielli E, Mosci P, Ernst J, et al. Immune response to Candida albicans is preserved despite defect in O-mannosylation of secretory proteins. Med Mycol. 2007;45:709-19 pubmed
	El Shikh M, El Sayed R, Wu Y, Szakal A, Tew J. TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity. J Immunol. 2007;179:4444-50 pubmed
	Crellin N, Garcia R, Hadisfar O, Allan S, Steiner T, Levings M. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol. 2005;175:8051-9 pubmed
	Konno K, Wakabayashi Y, Akashi Takamura S, Ishii T, Kobayashi M, Takahashi K, et al. A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. Biochem Biophys Res Commun. 2006;339:1076-82 pubmed
	Schaefer L, Babelova A, Kiss E, Hausser H, Baliova M, Krzyzankova M, et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest. 2005;115:2223-33 pubmed
	Jung D, Lee H, Jung B, Ock J, Lee M, Lee W, et al. TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. J Immunol. 2005;174:6467-76 pubmed

product information

master code :

NB100-56560

SKU :

NB100-56560

product name :

TLR4 Antibody (MTS510)

unit size :

0.1 mg (also 0.025 mg)

description :

The TLR4 Antibody (MTS510) from Novus is a rat monoclonal antibody to TLR4. This antibody reacts with flow,human,mouse. The TLR4 Antibody (MTS510) has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Flow (Cell Surface),Immunocytochemistry/ Immunofluorescence.

target :

TLR4

category :

Primary Antibodies

buffer :

PBS, 0.05% BSA

clonality :

Monoclonal

clone :

MTS510

concentration :

0.5 mg/ml

conjugate :

Unconjugated

host :

Rat

immunogen :

This TLR4 Antibody (MTS510) was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2 (Akashi et al, 2000).

isotype :

IgG2a Kappa

purity :

Protein G purified

species :

Flow,Human,Mouse

specificity :

This antibody preferentially recognizes TLR4-MD-2 complex than of TLR4 alone

theoretical molecular weight :

95.7 kDa

gene symbol :

TLR4

accessionNumbers :

O00206

applications :

Flow Cytometry,Immunoprecipitation,Flow (Cell Surface),Immunocytochemistry/ Immunofluorescence

USD :

239 USD

alt names :

ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, mts510, mts510 tlr4, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage