product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
S100A7/Psoriasin Antibody (47C1068) - BSA Free
catalog :
NB100-56559
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
47C1068
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 52
Published Application/Species/Sample/DilutionReference
  • western blot; human
de Castro A, Minty F, Hattinger E, Wolf R, Parkinson E. The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators. Longev Healthspan. 2014;3:8 pubmed publisher
  • immunohistochemistry; human
Mcheik J, Barrault C, Pedretti N, Garnier J, Juchaux F, Levard G, et al. Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children. Burns. 2015;41:352-8 pubmed publisher
  • immunohistochemistry; human; 1:50; fig 4
Rabeony H, Petit Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, et al. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1?, TNF? and oncostatin M. PLoS ONE. 2014;9:e101937 pubmed publisher
  • western blot; human
Teng X, Hu Z, Wei X, Wang Z, Guan T, Liu N, et al. IL-37 ameliorates the inflammatory process in psoriasis by suppressing proinflammatory cytokine production. J Immunol. 2014;192:1815-23 pubmed publisher
  • immunohistochemistry - frozen section; human
Ye L, Sun P, Martin T, Sanders A, Mason M, Jiang W. Psoriasin (S100A7) is a positive regulator of survival and invasion of prostate cancer cells. Urol Oncol. 2013;31:1576-83 pubmed publisher
  • immunohistochemistry - paraffin section; human
Nofech Mozes S, Spayne J, Rakovitch E, Kahn H, Seth A, Pignol J, et al. Biological Markers Predictive of Invasive Recurrence in DCIS. Clin Med Oncol. 2008;2:7-18 pubmed
  • western blot; human
Hashiramoto A, Yamane T, Tsumiyama K, Yoshida K, Komai K, Yamada H, et al. Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha. J Immunol. 2010;184:1560-5 pubmed publisher
  • western blot; human
Wolf R, Voscopoulos C, Winston J, Dharamsi A, Goldsmith P, Gunsior M, et al. Highly homologous hS100A15 and hS100A7 proteins are distinctly expressed in normal breast tissue and breast cancer. Cancer Lett. 2009;277:101-7 pubmed publisher
  • immunohistochemistry - frozen section; human
  • western blot; human
Wolf R, Howard O, Dong H, Voscopoulos C, Boeshans K, Winston J, et al. Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15. J Immunol. 2008;181:1499-506 pubmed
  • immunocytochemistry; human
Pene J, Chevalier S, Preisser L, Venereau E, Guilleux M, Ghannam S, et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol. 2008;180:7423-30 pubmed
  • western blot; human
Paruchuri V, Prasad A, McHugh K, Bhat H, Polyak K, Ganju R. S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation. PLoS ONE. 2008;3:e1741 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human
Boniface K, Diveu C, Morel F, Pedretti N, Froger J, Ravon E, et al. Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation. J Immunol. 2007;178:4615-22 pubmed
  • immunohistochemistry - paraffin section; human
Sa S, Valdez P, Wu J, Jung K, Zhong F, Hall L, et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol. 2007;178:2229-40 pubmed
  • immunohistochemistry - paraffin section; human
Gläser R, Harder J, Lange H, Bartels J, Christophers E, Schroder J. Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat Immunol. 2005;6:57-64 pubmed
Lundquist H, Andersson H, Chew M, Das J, Turkina M, Welin A. The Olfactomedin-4-Defined Human Neutrophil Subsets Differ in Proteomic Profile in Healthy Individuals and Patients with Septic Shock. J Innate Immun. 2022;:1-14 pubmed publisher
Todorovi x107 V, McDonald H, Hoover P, Wetter J, Marinopoulos A, Woody C, et al. Cytokine induced 3-D organotypic psoriasis skin model demonstrates distinct roles for NF-κB and JAK pathways in disease pathophysiology. Exp Dermatol. 2022;31:1036-1047 pubmed publisher
Bhatt T, Bhosale A, Bajantri B, Mathapathi M, Rizvi A, Scita G, et al. Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep. 2019;29:2546-2555.e4 pubmed publisher
Pathak P, Chiang J. Sterol 12α-Hydroxylase Aggravates Dyslipidemia by Activating the Ceramide/mTORC1/SREBP-1C Pathway via FGF21 and FGF15. Gene Expr. 2019;19:161-173 pubmed publisher
Garcia M, Morello E, Garnier J, Barrault C, Garnier M, Burucoa C, et al. Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis. Virulence. 2018;9:1163-1175 pubmed publisher
McMurphy T, Huang W, Queen N, Ali S, Widstrom K, Liu X, et al. Implementation of environmental enrichment after middle age promotes healthy aging. Aging (Albany NY). 2018;10:1698-1721 pubmed publisher
Li L, Cui Y, Ye L, Zhao Z, Jiang W, Ji J. Psoriasin overexpression confers drug resistance to cisplatin by activating ERK in gastric cancer. Int J Oncol. 2018;53:1171-1182 pubmed publisher
Bertelsen T, Iversen L, Johansen C. The human IL-17A/F heterodimer regulates psoriasis-associated genes through IκBζ. Exp Dermatol. 2018;27:1048-1052 pubmed publisher
Rosignoli C, Thibaut de Ménonville S, Orfila D, Béal M, Bertino B, Aubert J, et al. A topical treatment containing heat-treated Lactobacillus johnsonii NCC 533 reduces Staphylococcus aureus adhesion and induces antimicrobial peptide expression in an in vitro reconstructed human epidermis model. Exp Dermatol. 2018;27:358-365 pubmed publisher
Doebar S, Sieuwerts A, de Weerd V, Stoop H, Martens J, van Deurzen C. Gene Expression Differences between Ductal Carcinoma in Situ with and without Progression to Invasive Breast Cancer. Am J Pathol. 2017;187:1648-1655 pubmed publisher
Tian T, Li X, Hua Z, Ma J, Wu X, Liu Z, et al. S100A7 promotes the migration, invasion and metastasis of human cervical cancer cells through epithelial-mesenchymal transition. Oncotarget. 2017;8:24964-24977 pubmed publisher
McMurphy T, Huang W, Xiao R, Liu X, Dhurandhar N, Cao L. Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation. Diabetes. 2017;66:358-371 pubmed publisher
Bertelsen T, Ljungberg C, Boye Kjellerup R, Iversen L, Johansen C. IL-17F regulates psoriasis-associated genes through IκBζ. Exp Dermatol. 2017;26:234-241 pubmed publisher
Bianco K, Gormley M, Farrell J, Zhou Y, Oliverio O, Tilden H, et al. Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects. Prenat Diagn. 2016;36:812-22 pubmed publisher
Koerdt S, Steinstraesser L, Stoeckelhuber M, Wales C, Rohleder N, Babaryka G, et al. Radiotherapy for oral cancer decreases the cutaneous expression of host defence peptides. J Craniomaxillofac Surg. 2016;44:882-9 pubmed publisher
Chu Y, Liu S, Cheng H, Huang S, Chang Y, Chiang C, et al. Opposing Effects of Zac1 and Curcumin on AP-1-Regulated Expressions of S100A7. PLoS ONE. 2015;10:e0144175 pubmed publisher
Dey K, Sarkar S, Pal I, Das S, Dey G, Bharti R, et al. Mechanistic attributes of S100A7 (psoriasin) in resistance of anoikis resulting tumor progression in squamous cell carcinoma of the oral cavity. Cancer Cell Int. 2015;15:74 pubmed publisher
Zhao H, Wilkie T, Deol Y, Sneh A, Ganju A, Basree M, et al. miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer. Mol Cancer. 2015;14:11 pubmed publisher
Zhu L, Okano S, Takahara M, Chiba T, Tu Y, Oda Y, et al. Expression of S100 protein family members in normal skin and sweat gland tumors. J Dermatol Sci. 2013;70:211-9 pubmed publisher
Sneh A, Deol Y, Ganju A, Shilo K, Rosol T, Nasser M, et al. Differential role of psoriasin (S100A7) in estrogen receptor ? positive and negative breast cancer cells occur through actin remodeling. Breast Cancer Res Treat. 2013;138:727-39 pubmed publisher
Mcheik J, Barrault C, Pedretti N, Garnier J, Juchaux F, Levard G, et al. Foreskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts. J Tissue Eng Regen Med. 2016;10:252-60 pubmed publisher
Vegfors J, Petersson S, Kovács A, Polyak K, Enerback C. The expression of Psoriasin (S100A7) and CD24 is linked and related to the differentiation of mammary epithelial cells. PLoS ONE. 2012;7:e53119 pubmed publisher
Shubbar E, Vegfors J, Carlström M, Petersson S, Enerback C. Psoriasin (S100A7) increases the expression of ROS and VEGF and acts through RAGE to promote endothelial cell proliferation. Breast Cancer Res Treat. 2012;134:71-80 pubmed publisher
Kesting M, Mueller C, Wagenpfeil S, Stoeckelhuber M, Steiner T, Bauer F, et al. Quantitative comparison of the expression of antimicrobial peptides in the oral mucosa and extraoral skin. Br J Oral Maxillofac Surg. 2012;50:447-53 pubmed publisher
Garreis F, Gottschalt M, Schlorf T, Gläser R, Harder J, Worlitzsch D, et al. Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus. Invest Ophthalmol Vis Sci. 2011;52:4914-22 pubmed publisher
Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, et al. S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection. BMC Pulm Med. 2011;11:10 pubmed publisher
Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, et al. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1{alpha}, and TNF-{alpha} Recapitulates Some Features of Psoriasis. J Immunol. 2010;184:5263-5270 pubmed publisher
Kesting M, Sudhoff H, Hasler R, Nieberler M, Pautke C, Wolff K, et al. Psoriasin (S100A7) up-regulation in oral squamous cell carcinoma and its relation to clinicopathologic features. Oral Oncol. 2009;45:731-6 pubmed publisher
Zhang H, Zhao Q, Chen Y, Wang Y, Gao S, Mao Y, et al. Selective expression of S100A7 in lung squamous cell carcinomas and large cell carcinomas but not in adenocarcinomas and small cell carcinomas. Thorax. 2008;63:352-9 pubmed publisher
Petersson S, Bylander A, Yhr M, Enerback C. S100A7 (Psoriasin), highly expressed in ductal carcinoma in situ (DCIS), is regulated by IFN-gamma in mammary epithelial cells. BMC Cancer. 2007;7:205 pubmed
Zhang H, Wang Y, Chen Y, Sun S, Li N, Lv D, et al. Identification and validation of S100A7 associated with lung squamous cell carcinoma metastasis to brain. Lung Cancer. 2007;57:37-45 pubmed
Mehul B, Bernard D, Brouard M, Delattre C, Schmidt R. Influence of calcium on the proteolytic degradation of the calmodulin-like skin protein (calmodulin-like protein 5) in psoriatic epidermis. Exp Dermatol. 2006;15:469-77 pubmed
Krop I, März A, Carlsson H, Li X, Bloushtain Qimron N, Hu M, et al. A putative role for psoriasin in breast tumor progression. Cancer Res. 2005;65:11326-34 pubmed
Kennedy R, Gorski J, Quinn J, Stewart G, James C, Moore S, et al. BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene. Cancer Res. 2005;65:10265-72 pubmed
Boniface K, Bernard F, Garcia M, Gurney A, Lecron J, Morel F. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol. 2005;174:3695-702 pubmed
Martinsson H, Yhr M, Enerback C. Expression patterns of S100A7 (psoriasin) and S100A9 (calgranulin-B) in keratinocyte differentiation. Exp Dermatol. 2005;14:161-8 pubmed
Porter D, Lahti Domenici J, Keshaviah A, Bae Y, Argani P, Marks J, et al. Molecular markers in ductal carcinoma in situ of the breast. Mol Cancer Res. 2003;1:362-75 pubmed
Enerback C, Porter D, Seth P, Sgroi D, Gaudet J, Weremowicz S, et al. Psoriasin expression in mammary epithelial cells in vitro and in vivo. Cancer Res. 2002;62:43-7 pubmed
product information
master code :
NB100-56559
SKU :
NB100-56559
product name :
S100A7/Psoriasin Antibody (47C1068) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The S100A7/Psoriasin Antibody (47C1068) - BSA Free from Novus is a mouse monoclonal antibody to S100A7/Psoriasin. This antibody reacts with human,mouse. The S100A7/Psoriasin Antibody (47C1068) - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Electron Microscopy,Flow (Intracellular),Simple Western.
target :
S100A7/Psoriasin
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
47C1068
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This antibody was developed against recombinant psoriasin/HID-5 protein.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human,Mouse
gene symbol :
S100A7
Antibody validation :
Biological Validation
accessionNumbers :
P31151
applications :
IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Electron Microscopy,Flow (Intracellular),Simple Western
USD :
409 USD
alt names :
HID 5, HID5, HID-5, protein S100-A7, PSOR1, Psoriasin, psoriasin 1, S100 calcium binding protein A7, S100 calcium binding protein A7 (psoriasin 1), S100 calcium-binding protein A7, S100 calcium-binding protein A7 (psoriasin 1), S100A7c
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.