product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TEM7/PLXDC1 Antibody (197C193 (IM193)) - BSA Free
catalog :
NB100-56557
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
197C193 (IM193)
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:75; fig 1f
  • western blot; human; fig 1d
Carpenter R, Paw I, Zhu H, Sirkisoon S, Xing F, Watabe K, et al. The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis. Oncotarget. 2015;6:22653-65 pubmed
  • immunohistochemistry - frozen section; mouse
  • immunohistochemistry - frozen section; human
Mehran R, Nilsson M, Khajavi M, Du Z, Cascone T, Wu H, et al. Tumor endothelial markers define novel subsets of cancer-specific circulating endothelial cells associated with antitumor efficacy. Cancer Res. 2014;74:2731-41 pubmed publisher
  • immunohistochemistry - paraffin section; human
Yamaji Y, Yoshida S, Ishikawa K, Sengoku A, Sato K, Yoshida A, et al. TEM7 (PLXDC1) in neovascular endothelial cells of fibrovascular membranes from patients with proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci. 2008;49:3151-7 pubmed publisher
  • western blot; human
Nanda A, Buckhaults P, Seaman S, Agrawal N, Boutin P, Shankara S, et al. Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Res. 2004;64:8507-11 pubmed
Volpicelli F, Speranza L, Pulcrano S, de Gregorio R, Crispino M, de Sanctis C, et al. The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology. Mol Neurobiol. 2019;: pubmed publisher
Balzano M, De Grandis M, Vu Manh T, Chasson L, Bardin F, Farina A, et al. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Rep. 2019;26:3257-3271.e8 pubmed publisher
Ito M, Komai K, Mise Omata S, Iizuka Koga M, Noguchi Y, Kondo T, et al. Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Nature. 2019;565:246-250 pubmed publisher
Wixey J, Reinebrant H, Chand K, Buller K. Disruption to the 5-HT7 Receptor Following Hypoxia-Ischemia in the Immature Rodent Brain. Neurochem Res. 2018;43:711-720 pubmed publisher
Gautam J, Banskota S, Regmi S, Ahn S, Jeon Y, Jeong H, et al. Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling. Mol Cancer. 2016;15:75 pubmed
Holst K, Guseva D, Schindler S, Sixt M, Braun A, Chopra H, et al. The serotonin receptor 5-HT₇R regulates the morphology and migratory properties of dendritic cells. J Cell Sci. 2015;128:2866-80 pubmed publisher
Cho S, Ki H, Kim J, Oh J, Yang J, Kim W, et al. Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of rats. Korean J Anesthesiol. 2015;68:170-4 pubmed publisher
Speranza L, Giuliano T, Volpicelli F, De Stefano M, Lombardi L, Chambery A, et al. Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics. Front Behav Neurosci. 2015;9:62 pubmed publisher
Fuchs B, Mahlum E, Halder C, Maran A, Yaszemski M, Bode B, et al. High expression of tumor endothelial marker 7 is associated with metastasis and poor survival of patients with osteogenic sarcoma. Gene. 2007;399:137-43 pubmed
Meng F, Henson R, Patel T. Chemotherapeutic stress selectively activates NF-kappa B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells. Am J Physiol Cell Physiol. 2007;293:C749-60 pubmed
Lee H, Kang D, Seo I, Choi E, Park H, Park J. Expression of tumor endothelial marker 7 mRNA and protein in the dorsal root ganglion neurons of the rat. Neurosci Lett. 2006;402:71-5 pubmed
Lee H, Bae H, Park H, Seo I, Lee E, Suh D, et al. Cloning, characterization and neuronal expression profiles of tumor endothelial marker 7 in the rat brain. Brain Res Mol Brain Res. 2005;136:189-98 pubmed
product information
master code :
NB100-56557
SKU :
NB100-56557
product name :
TEM7/PLXDC1 Antibody (197C193 (IM193)) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TEM7/PLXDC1 Antibody (197C193 (IM193)) - BSA Free from Novus is a mouse monoclonal antibody to TEM7/PLXDC1. This antibody reacts with human,mouse,rat. The TEM7/PLXDC1 Antibody (197C193 (IM193)) - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation.
target :
TEM7/PLXDC1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
197C193 (IM193)
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Amino acids 409-425 (LQNNLSPKTKGTPVHLG) of human TEM7 were used to develop this monoclonal antibody.
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse,Rat
gene symbol :
PLXDC1
accessionNumbers :
Q8IUK5
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation
USD :
409 USD
alt names :
FLJ45632, plexin domain containing 1,2410003I07Rik, plexin domain-containing protein 1, TEM3FLJ36270, TEM7DKFZp686F0937, Tumor endothelial marker 3, Tumor endothelial marker 7
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.