Livin Antibody (88C570) - BSA Free | Novus Biologicals NB100-56548 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Livin Antibody (88C570) - BSA Free

catalog :

NB100-56548

quantity :

0.1 mg (also 0.025 mg)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

88C570

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

Novus Biologicals product webpage

citations: 29

Published Application/Species/Sample/Dilution	Reference
western blot; human	Shiloach T, Berens C, Danke C, Waiskopf O, Perlman R, Ben Yehuda D. tLivin displays flexibility by promoting alternative cell death mechanisms. PLoS ONE. 2014;9:e101075 pubmed publisher
western blot; human	Slagsvold J, Pettersen C, Størvold G, Follestad T, Krokan H, Schønberg S. DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. Nutr Cancer. 2010;62:611-21 pubmed publisher
western blot; human	Lazar I, Yaacov B, Shiloach T, Eliahoo E, Kadouri L, Lotem M, et al. The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin. J Virol. 2010;84:639-46 pubmed publisher
western blot; human	Fakler M, Loeder S, Vogler M, Schneider K, Jeremias I, Debatin K, et al. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood. 2009;113:1710-22 pubmed publisher
western blot; human	Wang H, Tan S, Wang X, Liu D, Yu C, Bai Z, et al. Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells. Acta Pharmacol Sin. 2007;28:1968-74 pubmed
western blot; human	Kleinberg L, Lie A, Flørenes V, Nesland J, Davidson B. Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma. Hum Pathol. 2007;38:986-94 pubmed
	Wu S, Xu Q, Sheng W, Su L, Zhu L. A novel role for Livin in the response to ultraviolet B radiation and pterygium development. Int J Mol Med. 2020;45:1103-1111 pubmed publisher
	Itoh K, Murata D, Kato T, Yamada T, Araki Y, Saito A, et al. Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division. elife. 2019;8: pubmed publisher
	Ganapathi M, Padgett L, Yamada K, Devinsky O, Willaert R, Person R, et al. Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. Am J Hum Genet. 2019;104:287-298 pubmed publisher
	Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed publisher
	Uchida S, Horie R, Sato H, Kai C, Yoneda M. Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1. Sci Rep. 2018;8:7682 pubmed publisher
	NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
	Hossain D, Ferreira Barbosa J, Cohen E, Tsang W. HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis. J Biol Chem. 2018;293:9448-9460 pubmed publisher
	Cartwright I, Liu X, Zhou M, Li F, Li C. Essential roles of Caspase-3 in facilitating Myc-induced genetic instability and carcinogenesis. elife. 2017;6: pubmed publisher
	Tchoghandjian A, Soubéran A, Tabouret E, Colin C, Denicolaï E, Jiguet Jiglaire C, et al. Inhibitor of apoptosis protein expression in glioblastomas and their in vitro and in vivo targeting by SMAC mimetic GDC-0152. Cell Death Dis. 2016;7:e2325 pubmed publisher
	Landin Malt A, Cagliero J, Legent K, Silber J, Zider A, Flagiello D. Alteration of TEAD1 expression levels confers apoptotic resistance through the transcriptional up-regulation of Livin. PLoS ONE. 2012;7:e45498 pubmed publisher
	Liu X, Wang A, Gao H, Yuan Z, Jiao Y. Expression and role of the inhibitor of apoptosis protein livin in chemotherapy sensitivity of ovarian carcinoma. Int J Oncol. 2012;41:1021-8 pubmed publisher
	Lazar I, Perlman R, Lotem M, Peretz T, Ben Yehuda D, Kadouri L. The clinical effect of the inhibitor of apopotosis protein livin in melanoma. Oncology. 2012;82:197-204 pubmed publisher
	Crnkovic Mertens I, Wagener N, Semzow J, Gröne E, Haferkamp A, Hohenfellner M, et al. Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis. Cell Mol Life Sci. 2007;64:1137-44 pubmed
	Nachmias B, Lazar I, Elmalech M, Abed El Rahaman I, Asshab Y, Mandelboim O, et al. Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin. Apoptosis. 2007;12:1129-42 pubmed
	Gordon G, Mani M, Mukhopadhyay L, Dong L, Yeap B, Sugarbaker D, et al. Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma. J Pathol. 2007;211:439-46 pubmed
	Gordon G, Mani M, Mukhopadhyay L, Dong L, Edenfield H, Glickman J, et al. Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma. J Pathol. 2007;211:447-54 pubmed
	Choi J, Hwang Y, Sung K, Lee S, Yoo K, Jung H, et al. Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia. Blood. 2007;109:471-7 pubmed
	Ma L, Huang Y, Song Z, Feng S, Tian X, Du W, et al. Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway. Cell Death Differ. 2006;13:2079-88 pubmed
	Crnkovic Mertens I, Semzow J, Hoppe Seyler F, Butz K. Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells. J Mol Med (Berl). 2006;84:232-40 pubmed
	Qiuping Z, Jei X, Youxin J, Wei J, Chun L, Jin W, et al. CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of livin activation. Cancer Res. 2004;64:7579-87 pubmed
	Yang Q, Du C. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells. J Biol Chem. 2004;279:16963-70 pubmed
	Crnkovic Mertens I, Hoppe Seyler F, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene. 2003;22:8330-6 pubmed
	Nachmias B, Ashhab Y, Bucholtz V, Drize O, Kadouri L, Lotem M, et al. Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma. Cancer Res. 2003;63:6340-9 pubmed

product information

master code :

NB100-56548

SKU :

NB100-56548

product name :

Livin Antibody (88C570) - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The Livin Antibody (88C570) - BSA Free from Novus is a mouse monoclonal antibody to Livin. This antibody reacts with human. The Livin Antibody (88C570) - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence.

target :

Livin

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

88C570

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant human livin protein was used as immunogen.

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human

specificity :

The Livin antibody, clone 88C570 has been shown to recognize both Livin alpha (~39 kDa) and Livin beta (~37 kDa) isoforms (Nachmias et al, 2003)

gene symbol :

BIRC7

accessionNumbers :

Q96CA5

applications :

Western Blot,Immunocytochemistry/ Immunofluorescence

USD :

409 USD

alt names :

baculoviral IAP repeat containing 7, baculoviral IAP repeat-containing 7, KIAPRING finger protein 50, Kidney inhibitor of apoptosis protein, Livin, livin inhibitor-of-apoptosis, Melanoma inhibitor of apoptosis protein, MLIAPlivin inhibitor of apoptosis, ML-IAPmliap, RNF50LIVINbaculoviral IAP repeat-containing protein 7

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage