MBD1 Antibody (100B272.1) - BSA Free | Novus Biologicals NB100-56537 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MBD1 Antibody (100B272.1) - BSA Free

catalog :

NB100-56537

quantity :

0.1 mg (also 0.025 mg)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

100B272.1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 41

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse western blot; mouse chromatin immunoprecipitation; human western blot; human	Varshney D, Vavrova Anderson J, Oler A, Cowling V, Cairns B, White R. SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation. Nat Commun. 2015;6:6569 pubmed publisher
western blot; human	Hendriks I, Treffers L, Verlaan de Vries M, Olsen J, Vertegaal A. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. Cell Rep. 2015;10:1778-1791 pubmed publisher
immunohistochemistry - frozen section; mouse immunoprecipitation; mouse western blot; mouse immunohistochemistry - frozen section; human immunoprecipitation; human western blot; human	Waterfield M, Khan I, Cortez J, Fan U, Metzger T, Greer A, et al. The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat Immunol. 2014;15:258-65 pubmed publisher
western blot; mouse	Ruddock D Cruz N, Xue J, Wilson K, Heffernan C, Prashadkumar S, Cooney M, et al. Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development. Mol Reprod Dev. 2008;75:48-59 pubmed
	Petrovi x107 D, Jage x10d i x107 D, Krasi x107 J, Sin x10d i x107 N, Mitre x10d i x107 D. Effect of Fetal Bovine Serum or Basic Fibroblast Growth Factor on Cell Survival and the Proliferation of Neural Stem Cells: The Influence of Homocysteine Treatment. Int J Mol Sci. 2023;24: pubmed publisher
	Zhao C, Miao J, Sun R, Liang R, Chen W, Gao Y, et al. MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer. Aging (Albany NY). 2022;14:5878-5894 pubmed publisher
	Bielle F, Di Stefano A, Meyronet D, Picca A, Villa C, Bernier M, et al. Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features. Brain Pathol. 2017;: pubmed publisher
	Breton Q, Plouhinec H, Prunier Mirebeau D, Boisselier B, Michalak S, Menei P, et al. BRAF-V600E immunohistochemistry in a large series of glial and glial-neuronal tumors. Brain Behav. 2017;7:e00641 pubmed publisher
	Bielle F, Ducray F, Mokhtari K, Dehais C, Adle Biassette H, Carpentier C, et al. Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas. Brain Pathol. 2017;27:567-579 pubmed publisher
	Matsumura N, Nobusawa S, Ikota H, Hirato J, Hirose T, Yokoo H, et al. Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors. Brain Tumor Pathol. 2015;32:261-7 pubmed publisher
	Nagaishi M, Yokoo H, Nobusawa S, Fujii Y, Sugiura Y, Suzuki R, et al. Localized overexpression of alpha-internexin within nodules in multinodular and vacuolating neuronal tumors. Neuropathology. 2015;35:561-8 pubmed publisher
	Figarella Branger D, Mokhtari K, Dehais C, Jouvet A, Uro Coste E, Colin C, et al. Mitotic index, microvascular proliferation, and necrosis define 3 groups of 1p/19q codeleted anaplastic oligodendrogliomas associated with different genomic alterations. Neuro Oncol. 2014;16:1244-54 pubmed publisher
	Reyes Botero G, Giry M, Mokhtari K, Labussiere M, Idbaih A, Delattre J, et al. Molecular analysis of diffuse intrinsic brainstem gliomas in adults. J Neurooncol. 2014;116:405-11 pubmed publisher
	Nagaishi M, Suzuki A, Nobusawa S, Yokoo H, Nakazato Y. Alpha-internexin and altered CIC expression as a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion. Brain Tumor Pathol. 2014;31:257-64 pubmed publisher
	Takano S, Kato Y, Yamamoto T, Kaneko M, Ishikawa E, Tsujimoto Y, et al. Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. J Neurooncol. 2012;108:361-73 pubmed publisher
	Seilhean D, Le Ber I, Sarazin M, Lacomblez L, Millecamps S, Salachas F, et al. Fronto-temporal lobar degeneration: neuropathology in 60 cases. J Neural Transm (Vienna). 2011;118:753-64 pubmed publisher
	Mokhtari K, Ducray F, Kros J, Gorlia T, Idbaih A, Taphoorn M, et al. Alpha-internexin expression predicts outcome in anaplastic oligodendroglial tumors and may positively impact the efficacy of chemotherapy: European organization for research and treatment of cancer trial 26951. Cancer. 2011;117:3014-26 pubmed publisher
	San Millan B, Kaci R, Polivka M, Robert G, Heran F, Gueguen A, et al. [Gliomatosis cerebri: a biopsy and autopsy case report]. Ann Pathol. 2010;30:25-9 pubmed publisher
	Kumar D, Verma M. Methods in cancer epigenetics and epidemiology. Methods Mol Biol. 2009;471:273-88 pubmed publisher
	Villa R, Pasini D, Gutierrez A, Morey L, Occhionorelli M, Viré E, et al. Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell. 2007;11:513-25 pubmed
	Wang P, Wang S, Hsieh C, Chien C. Neural expression of alpha-internexin promoter in vitro and in vivo. J Cell Biochem. 2006;97:275-87 pubmed
	Ko T, Chien C, Lu K. The expression of alpha-internexin and peripherin in the developing mouse pineal gland. J Biomed Sci. 2005;12:777-89 pubmed
	Rauch U, Klotz M, Maas Omlor S, Wink E, Hänsgen A, Hagl C, et al. Expression of intermediate filament proteins and neuronal markers in the human fetal gut. J Histochem Cytochem. 2006;54:39-46 pubmed
	Uchikado H, Shaw G, Wang D, Dickson D. Screening for neurofilament inclusion disease using alpha-internexin immunohistochemistry. Neurology. 2005;64:1658-9 pubmed
	Chien C, Liu T, Ho C, Lu K. Overexpression of neuronal intermediate filament protein alpha-internexin in PC12 cells. J Neurosci Res. 2005;80:693-706 pubmed
	Jing Ping Z, Tian Q, Sakagami H, Kondo H, Endo S, Suzuki T. p55 protein is a member of PSD scaffold proteins in the rat brain and interacts with various PSD proteins. Brain Res Mol Brain Res. 2005;135:204-16 pubmed
	Josephs K, Uchikado H, McComb R, Bashir R, Wszolek Z, Swanson J, et al. Extending the clinicopathological spectrum of neurofilament inclusion disease. Acta Neuropathol. 2005;109:427-32 pubmed
	Cairns N, Grossman M, Arnold S, Burn D, Jaros E, Perry R, et al. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 2004;63:1376-84 pubmed
	Rajasalu T, Teesalu K, Janmey P, Uibo R. Demonstration of natural autoantibodies against the neurofilament protein alpha-internexin in sera of patients with endocrine autoimmunity and healthy individuals. Immunol Lett. 2004;94:153-60 pubmed
	Cairns N, Uryu K, Bigio E, Mackenzie I, Gearing M, Duyckaerts C, et al. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathol. 2004;108:213-23 pubmed
	Cairns N, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie I, et al. alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. Am J Pathol. 2004;164:2153-61 pubmed
	Yuan A, Rao M, Kumar A, Julien J, Nixon R. Neurofilament transport in vivo minimally requires hetero-oligomer formation. J Neurosci. 2003;23:9452-8 pubmed
	Ortino B, Inverardi F, Morante Oria J, Fairen A, Frassoni C. Substrates and routes of migration of early generated neurons in the developing rat thalamus. Eur J Neurosci. 2003;18:323-32 pubmed
	Donner L, Teshima I. Peripheral medulloepithelioma: an immunohistochemical, ultrastructural, and cytogenetic study of a rare, chemotherapy-sensitive, pediatric tumor. Am J Surg Pathol. 2003;27:1008-12 pubmed
	Reese B, Bachman K, Baylin S, Rountree M. The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. Mol Cell Biol. 2003;23:3226-36 pubmed
	Stachowiak E, Fang X, Myers J, Dunham S, Stachowiak M. cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1). J Neurochem. 2003;84:1296-312 pubmed
	Talbot N, Powell A, Garrett W. Spontaneous differentiation of porcine and bovine embryonic stem cells (epiblast) into astrocytes or neurons. In Vitro Cell Dev Biol Anim. 2002;38:191-7 pubmed
	McGraw T, Mickle J, Shaw G, Streit W. Axonally transported peripheral signals regulate alpha-internexin expression in regenerating motoneurons. J Neurosci. 2002;22:4955-63 pubmed
	Larivière R, Nguyen M, Ribeiro da Silva A, Julien J. Reduced number of unmyelinated sensory axons in peripherin null mice. J Neurochem. 2002;81:525-32 pubmed
	Shaw G, Morse S, Ararat M, Graham F. Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 2002;16:869-71 pubmed
	Evans J, Sumners C, Moore J, Huentelman M, Deng J, Gelband C, et al. Characterization of mitotic neurons derived from adult rat hypothalamus and brain stem. J Neurophysiol. 2002;87:1076-85 pubmed

product information

master code :

NB100-56537

SKU :

NB100-56537

product name :

MBD1 Antibody (100B272.1) - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The MBD1 Antibody (100B272.1) - BSA Free from Novus is a mouse monoclonal antibody to MBD1. This antibody reacts with human,mouse. The MBD1 Antibody (100B272.1) - BSA Free has been validated for the following applications: Western Blot,Chemotaxis,Immunoprecipitation,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Knockdown Validated.

target :

MBD1

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

100B272.1

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 391-405 (SESEDGAGSPPPYRR) of human MBD1; GenBank no ref NP_056671.2

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse

specificity :

There are many isoforms of human MBD1 ranging from 503 (~55 kDa) to 655 (~71 kDa) amino acids in length

gene symbol :

MBD1

Antibody validation :

Knockout/Knockdown

accessionNumbers :

Q9UIS9

applications :

Western Blot,Chemotaxis,Immunoprecipitation,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Knockdown Validated

USD :

409 USD

alt names :

CXXC-type zinc finger protein 3, methyl-CpG binding domain protein 1, methyl-CpG binding domain protein 1 isoform PCM1, methyl-CpG-binding domain protein 1, Methyl-CpG-binding protein MBD1, PCM1CXXC3RFT, Protein containing methyl-CpG-binding domain 1, the regulator of fibroblast growth factor 2 (FGF-2) transcription

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage