product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TRAILR1/TNFRSF10A Antibody (32A242) - BSA Free
catalog :
NB100-56528
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32A242
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
citations: 9
Reference
Lee S, Quan K, Byun H, Park I, Kang K, Piao X, et al. Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis. Sci Rep. 2019;9:13505 pubmed publisher
López de Maturana R, Lang V, Zubiarrain A, Sousa A, Vázquez N, Gorostidi A, et al. Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons. J Neuroinflammation. 2016;13:295 pubmed
Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, et al. CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway. Oncotarget. 2016;7:27787-801 pubmed publisher
Di X, Zhang G, Zhang Y, Takeda K, Rivera Rosado L, Zhang B. Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5. Oncotarget. 2013;4:1349-64 pubmed
Brooks A, Jacobsen K, Li W, Shanker A, Sayers T. Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex. Mol Cancer Res. 2010;8:729-38 pubmed publisher
Laguinge L, Samara R, Wang W, El Deiry W, Corner G, Augenlicht L, et al. DR5 receptor mediates anoikis in human colorectal carcinoma cell lines. Cancer Res. 2008;68:909-17 pubmed publisher
Xu J, Zhou J, Wu G. Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy. Cancer Res. 2006;66:10092-9 pubmed
Cisternas P, Moreno R. Comparative analysis of apoptotic pathways in rat, mouse, and hamster spermatozoa. Mol Reprod Dev. 2006;73:1318-25 pubmed
Jin F, Liu X, Zhou Z, Yue P, Lotan R, Khuri F, et al. Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells. Cancer Res. 2005;65:6354-63 pubmed
product information
master code :
NB100-56528
SKU :
NB100-56528
product name :
TRAILR1/TNFRSF10A Antibody (32A242) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TRAILR1/TNFRSF10A Antibody (32A242) - BSA Free from Novus is a mouse monoclonal antibody to TRAILR1/TNFRSF10A. This antibody reacts with human,mouse,rat. The TRAILR1/TNFRSF10A Antibody (32A242) - BSA Free has been validated for the following applications: Western Blot,Immunoblotting,Immunocytochemistry/ Immunofluorescence.
target :
TRAILR1/TNFRSF10A
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
32A242
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse,Rat
gene symbol :
TNFRSF10A
accessionNumbers :
O00220
applications :
Western Blot,Immunoblotting,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
APO2, CD261, CD261 antigen, cytotoxic TRAIL receptor, Death receptor 4, DR4, DR4 TRAIL receptor 1, TNF-related apoptosis inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TRAIL-R1, TRAILR-1, TRAILR1MGC9365, tumor necrosis factor receptor superfamily member 10A, tumor necrosis factor receptor superfamily, member 10a
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.