Caspase-8 Antibody (90A992) - BSA Free | Novus Biologicals NB100-56527 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Caspase-8 Antibody (90A992) - BSA Free

catalog :

NB100-56527

quantity :

0.1 mg (also 0.025 mg)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

90A992

reactivity :

human, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
western blot; human	Hsuan S, Chyau C, Hung H, Chen J, Chou F. The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer. Eur J Nutr. 2016;55:491-503 pubmed publisher
western blot; human	Cheng T, Lai C, Chung M, Kalyanam N, Majeed M, Ho C, et al. Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors. PLoS ONE. 2014;9:e111814 pubmed publisher
	Hagi T, Vangveravong S, Takchi R, Gong Q, Goedegebuure S, Tiriac H, et al. The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer. Sci Rep. 2024;14:6373 pubmed publisher
	Corry J, Kettenburg G, Upadhyay A, Wallace M, Marti M, Wonderlich E, et al. Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates. PLoS Pathog. 2022;18:e1010395 pubmed publisher
	Munro M, Peng L, Wickremesekera S, Tan S. Colon adenocarcinoma-derived cells that express induced-pluripotent stem cell markers possess stem cell function. PLoS ONE. 2020;15:e0232934 pubmed publisher
	Muller I, Strozyk E, Schindler S, Beissert S, Oo H, Sauter T, et al. Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Mol Cell. 2020;77:970-984.e7 pubmed publisher
	Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, et al. Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma. Mol Cancer. 2019;18:159 pubmed publisher
	Munro M, Wickremesekera S, Peng L, Marsh R, Itinteang T, Tan S. Cancer stem cell subpopulations in primary colon adenocarcinoma. PLoS ONE. 2019;14:e0221963 pubmed publisher
	Koh S, Brasch H, de Jongh J, Itinteang T, Tan S. Cancer stem cell subpopulations in moderately differentiated head and neck cutaneous squamous cell carcinoma. Heliyon. 2019;5:e02257 pubmed publisher
	Zhu Y, Chen H, Zhao X, Li B, He H, Cheng H, et al. Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats. Toxicol Lett. 2019;314:63-74 pubmed publisher
	Wang Y, Wang K, Chen Y, Zhou J, Liang Y, Yang X, et al. Mutational landscape of penile squamous cell carcinoma in a Chinese population. Int J Cancer. 2019;145:1280-1289 pubmed publisher
	Choi H, Ryu K, Roh J. Krüppel-like factor 4 plays a role in the luteal transition in steroidogenesis by downregulating Cyp19A1 expression. Am J Physiol Endocrinol Metab. 2019;316:E1071-E1080 pubmed publisher
	Eady E, Brasch H, de Jongh J, Marsh R, Tan S, Itinteang T. Expression of Embryonic Stem Cell Markers in Microcystic Lymphatic Malformation. Lymphat Res Biol. 2019;17:496-503 pubmed publisher
	Shivapathasundram G, Wickremesekera A, Brasch H, Marsh R, Tan S, Itinteang T. Expression of Embryonic Stem Cell Markers on the Microvessels of WHO Grade I Meningioma. Front Surg. 2018;5:65 pubmed publisher
	Fernandez N, Wrzosek L, Radziwill Bienkowska J, Ringot Destrez B, Duviau M, Noordine M, et al. Characterization of Mucus-Related Properties of Streptococcus thermophilus: From Adhesion to Induction. Front Physiol. 2018;9:980 pubmed publisher
	Humphries H, Wickremesekera S, Marsh R, Brasch H, Mehrotra S, Tan S, et al. Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver. Front Surg. 2017;4:76 pubmed publisher
	Jia Y, Zhou J, Luo X, Chen M, Chen Y, Wang J, et al. KLF4 overcomes tamoxifen resistance by suppressing MAPK signaling pathway and predicts good prognosis in breast cancer. Cell Signal. 2018;42:165-175 pubmed publisher
	Tang X, Liu K, HAMBLIN M, Xu Y, Yin K. Genetic Deletion of Krüppel-Like Factor 11 Aggravates Ischemic Brain Injury. Mol Neurobiol. 2018;55:2911-2921 pubmed publisher
	Zhou H, Liu Y, Zhu R, Ding F, Wan Y, Li Y, et al. FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation. Oncogene. 2017;36:3312-3321 pubmed publisher
	Greenberg D, Sturdevant D, Marshall Batty K, Chu J, Pettinato A, Virtaneva K, et al. Simultaneous Host-Pathogen Transcriptome Analysis during Granulibacter bethesdensis Infection of Neutrophils from Healthy Subjects and Patients with Chronic Granulomatous Disease. Infect Immun. 2015;83:4277-92 pubmed publisher
	Schultz C, Golembieski W, King D, Brown S, Brodie C, Rempel S. Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival. Mol Cancer. 2012;11:20 pubmed publisher
	Berges C, Haberstock H, Fuchs D, Sadeghi M, Opelz G, Daniel V, et al. Proteasome inhibition activates the mitochondrial pathway of apoptosis in human CD4+ T cells. J Cell Biochem. 2009;108:935-46 pubmed publisher
	Berges C, Fuchs D, Opelz G, Daniel V, Naujokat C. Helenalin suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms. Mol Immunol. 2009;46:2892-901 pubmed publisher

product information

master code :

NB100-56527

SKU :

NB100-56527

product name :

Caspase-8 Antibody (90A992) - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The Caspase-8 Antibody (90A992) - BSA Free from Novus is a mouse monoclonal antibody to Caspase-8. This antibody reacts with human,insect - drosophila melanogaster,primate,primate - macaca mulatta (rhesus macaque). The Caspase-8 Antibody (90A992) - BSA Free has been validated for the following applications: Simple Western,IF/IHC,Western Blot,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready.

target :

Caspase-8

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

90A992

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

The immunogen for this product falls between amino acids 360-385 of the human Caspase 8 protein.

isotype :

IgG1

purity :

Protein G purified

species :

Human,Insect - Drosophila melanogaster,Primate,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

This can be used for detection of the pro-form of Caspase-8

gene symbol :

CASP8

Antibody validation :

Biological Validation

applications :

Simple Western,IF/IHC,Western Blot,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready

USD :

399 USD

alt names :

AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage