product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
IKK beta Antibody (10A9B6) - BSA Free
catalog :
NB100-56513
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10A9B6
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, EMSA, immunohistochemistry - frozen section
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse
Paul S, Traver M, Kashyap A, Washington M, Latoche J, Schaefer B. T cell receptor signals to NF-κB are transmitted by a cytosolic p62-Bcl10-Malt1-IKK signalosome. Sci Signal. 2014;7:ra45 pubmed publisher
  • western blot; human
Tare N, Li H, Morschauser A, Cote Sierra J, Ju G, Renzetti L, et al. KU812 cells provide a novel in vitro model of the human IL-33/ST2L axis: functional responses and identification of signaling pathways. Exp Cell Res. 2010;316:2527-37 pubmed publisher
Choi H, Kim Y, Mirzaaghasi A, Heo J, Kim Y, Shin J, et al. Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality. Sci Adv. 2020;6:eaaz6980 pubmed publisher
Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery. J Exp Clin Cancer Res. 2019;38:62 pubmed publisher
Bakkar N, Ladner K, Canan B, Liyanarachchi S, Bal N, Pant M, et al. IKK? and alternative NF-?B regulate PGC-1? to promote oxidative muscle metabolism. J Cell Biol. 2012;196:497-511 pubmed publisher
Yang G, Rosen D, Liu G, Yang F, Guo X, Xiao X, et al. CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin Cancer Res. 2010;16:3875-86 pubmed publisher
Monsalve E, Ruiz García A, Baladron V, Ruiz Hidalgo M, Sánchez Solana B, Rivero S, et al. Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity. Eur J Immunol. 2009;39:2556-70 pubmed publisher
Scott M, Billiar T. Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes. J Biol Chem. 2008;283:29433-46 pubmed publisher
Lamothe B, Campos A, Webster W, Gopinathan A, Hur L, Darnay B. The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL. J Biol Chem. 2008;283:24871-80 pubmed publisher
Vacca A, Felli M, Palermo R, Di Mario G, Calce A, Di Giovine M, et al. Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. EMBO J. 2006;25:1000-8 pubmed
Fitzgerald K, McWhirter S, Faia K, Rowe D, Latz E, Golenbock D, et al. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol. 2003;4:491-6 pubmed
product information
master code :
NB100-56513
SKU :
NB100-56513
product name :
IKK beta Antibody (10A9B6) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The IKK beta Antibody (10A9B6) - BSA Free from Novus is a mouse monoclonal antibody to IKK beta. This antibody reacts with human,mouse. The IKK beta Antibody (10A9B6) - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,EMSA,Western Blot,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,Gel Super Shift Assays,Flow (Intracellular),Simple Western.
target :
IKK beta
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
10A9B6
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full-length human IKKb/IKK2 recombinant protein was used as immunogen (NP_001547).
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human,Mouse
gene symbol :
IKBKB
accessionNumbers :
O14920
applications :
Immunocytochemistry/ Immunofluorescence,EMSA,Western Blot,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,Gel Super Shift Assays,Flow (Intracellular),Simple Western
USD :
409 USD
alt names :
EC 2.7.11, EC 2.7.11.10, I-kappa-B kinase 2, I-kappa-B-kinase beta, IkBKB, IKK2FLJ38368, IKK-B, IKK-betaFLJ36218, IKKBFLJ40509, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKBFLJ33771, Nuclear factor NF-kappa-B inhibitor kinase beta
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.