| Published Application/Species/Sample/Dilution | Reference |
|---|
- chromatin immunoprecipitation; mouse
- western blot; mouse
| Shao J, Zhang Y, Yang T, Qi J, Zhang L, Deng L. HIF-1α disturbs osteoblasts and osteoclasts coupling in bone remodeling by up-regulating OPG expression. In Vitro Cell Dev Biol Anim. 2015;51:808-14 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Callegari A, Coons M, Ricks J, Rosenfeld M, Scatena M. Increased calcification in osteoprotegerin-deficient smooth muscle cells: Dependence on receptor activator of NF-?B ligand and interleukin 6. J Vasc Res. 2014;51:118-31 pubmed publisher |
| Mine Y, Makihira S, Yamaguchi Y, Tanaka H, Nikawa H. Involvement of ERK and p38 MAPK pathways on Interleukin-33-induced RANKL expression in osteoblastic cells. Cell Biol Int. 2014;38:655-62 pubmed publisher |
- immunohistochemistry - paraffin section; rat
| Kim R, Oh J, Lee B, Seo Y, Hwang S, Kim I. The effect of dose on rhBMP-2 signaling, delivered via collagen sponge, on osteoclast activation and in vivo bone resorption. Biomaterials. 2014;35:1869-81 pubmed publisher |
- immunohistochemistry - paraffin section; human
| Gambichler T, Terras S, Kampilafkos P, Kreuter A, Skrygan M. T regulatory cells and related immunoregulatory factors in polymorphic light eruption following ultraviolet A1 challenge. Br J Dermatol. 2013;169:1288-94 pubmed publisher |
- immunohistochemistry; rat
| Yin Y, Schluesener H, Zhang Z, Zhang Z. Lesional infiltration of receptor activator of nuclear factor-?B ligand? cells in experimental autoimmune neuritis rats. Neurol Sci. 2013;34:905-9 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Boyce A, Chong W, Yao J, Gafni R, Kelly M, Chamberlain C, et al. Denosumab treatment for fibrous dysplasia. J Bone Miner Res. 2012;27:1462-70 pubmed publisher |
- immunocytochemistry; human
- immunohistochemistry; human
| Hu P, Chu G, Zhu G, Yang H, Luthringer D, Prins G, et al. Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer. PLoS ONE. 2011;6:e28670 pubmed publisher |
| Parrula C, Zimmerman B, Nadella P, Shu S, Rosol T, Fernandez S, et al. Expression of tumor invasion factors determines systemic engraftment and induction of humoral hypercalcemia in a mouse model of adult T-cell leukemia. Vet Pathol. 2009;46:1003-14 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Ghoreishi M, Bach P, Obst J, Komba M, Fleet J, Dutz J. Expansion of antigen-specific regulatory T cells with the topical vitamin d analog calcipotriol. J Immunol. 2009;182:6071-8 pubmed publisher |
- immunohistochemistry - paraffin section; human
| Neidhart M, Baraliakos X, Seemayer C, Zelder C, Gay R, Michel B, et al. Expression of cathepsin K and matrix metalloproteinase 1 indicate persistent osteodestructive activity in long-standing ankylosing spondylitis. Ann Rheum Dis. 2009;68:1334-9 pubmed publisher |
| Wei F, Hughes M, Omer M, Ngo C, Pugazhendhi A, Kolanthai E, et al. A Multifunctional Therapeutic Strategy Using P7C3 as A Countermeasure Against Bone Loss and Fragility in An Ovariectomized Rat Model of Postmenopausal Osteoporosis. Adv Sci (Weinh). 2024;11:e2308698 pubmed publisher |
| Odo A, Kunimatsu R, Abe T, Sakata S, Nakatani A, Rikitake K, et al. Stem cells derived from human exfoliated deciduous teeth-based media in a rat root resorption model. Arch Oral Biol. 2024;158:105854 pubmed publisher |
| Zhao L, Lai Y, Jiao H, Huang J. Nerve Growth Factor Receptor Limits Inflammation to Promote Remodeling and Repair of Osteoarthritic Joints. bioRxiv. 2023;: pubmed publisher |
| Ding Y, Yang Y, Xu F, Tan Z, Liu X, Shao X, et al. Early protection against bone stress injuries by mobilization of endogenous targeted bone remodeling. iScience. 2023;26:107605 pubmed publisher |
| Hild V, Mellert K, M xf6 ller P, Barth T. Giant Cells of Various Lesions Are Characterised by Different Expression Patterns of HLA-Molecules and Molecules Involved in the Cell Cycle, Bone Metabolism, and Lineage Affiliation: An Immunohistochemical Study with a Review of the Literature. Cancers (Basel). 2023;15: pubmed publisher |
| Wei F, Tuong Z, Omer M, Ngo C, Asiatico J, Kinzel M, et al. A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss. Bone Res. 2023;11:34 pubmed publisher |
| Liu J, Yue J, Wang K, Zhou L, Mao H, Chen Z, et al. Tertiary Lymphoid Structures Are Related to Inflammatory Progression and Bone Loss in Human Apical Periodontitis. J Endod. 2023;49:1138-1144 pubmed publisher |
| Wei F, Neal C, Sakthivel T, Fu Y, Omer M, Adhikary A, et al. A novel approach for the prevention of ionizing radiation-induced bone loss using a designer multifunctional cerium oxide nanozyme. Bioact Mater. 2023;21:547-565 pubmed publisher |
| Kunimatsu R, Kimura A, Sakata S, Tsuka Y, Yoshimi Y, Abe T, et al. Effects of baicalin on the proliferation and expression of OPG and RANKL in human cementoblast-lineage cells. J Dent Sci. 2022;17:162-169 pubmed publisher |
| Lysitska A, Galanis N, Skandalos I, Nikolaidou C, Briza S, Fylaktou A, et al. Histology and Immunohistochemistry of Radial Arteries Are Suggestive of an Interaction between Calcification and Early Atherosclerotic Lesions in Chronic Kidney Disease. Medicina (Kaunas). 2021;57: pubmed publisher |
| Liu X, Zhu R, Luo Y, Wang S, Zhao Y, Qiu Z, et al. Distinct human Langerhans cell subsets orchestrate reciprocal functions and require different developmental regulation. Immunity. 2021;54:2305-2320.e11 pubmed publisher |
| Nakao Y, Fukuda T, Zhang Q, Sanui T, Shinjo T, Kou X, et al. Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss. Acta Biomater. 2021;122:306-324 pubmed publisher |
| Kunimatsu R, Kimura A, Tsuka Y, Horie K, Yoshimi Y, Awada T, et al. Baicalin inhibits root resorption during tooth movement in a rodent model. Arch Oral Biol. 2020;116:104770 pubmed publisher |
| Hong H, Hosomichi J, Maeda H, Lekvijittada K, Oishi S, Ishida Y, et al. Intermittent hypoxia retards mandibular growth and alters RANKL expression in adolescent and juvenile rats. Eur J Orthod. 2020;: pubmed publisher |
| Sato N, Kumasawa K, Yamashita M, Miyake T, Nakamura H, Kimura T. Therapeutic potential of combination therapy of soluble VEGF receptor 1 and conventional chemotherapy for ovarian cancer growth. J Obstet Gynaecol Res. 2020;46:636-645 pubmed publisher |
| Zhou J, Huang D, Zhu M, Gao C, Yan H, Li X, et al. Wnt/β-catenin-mediated heat exposure inhibits intestinal epithelial cell proliferation and stem cell expansion through endoplasmic reticulum stress. J Cell Physiol. 2020;235:5613-5627 pubmed publisher |
| Liu X, Li W, Cai J, Yan Z, Shao X, Xie K, et al. Spatiotemporal characterization of microdamage accumulation and its targeted remodeling mechanisms in diabetic fatigued bone. FASEB J. 2020;34:2579-2594 pubmed publisher |
| Jin C, Ye J, Yang J, Gao C, Yan H, Li H, et al. mTORC1 Mediates Lysine-Induced Satellite Cell Activation to Promote Skeletal Muscle Growth. Cells. 2019;8: pubmed publisher |
| Zhao S, Zhong S, Wang F, Wang H, Xu D, Li G. Microcystin-LR exposure decreased the fetal weight of mice by disturbance of placental development and ROS-mediated endoplasmic reticulum stress in the placenta. Environ Pollut. 2020;256:113362 pubmed publisher |
| Zhou J, Wang Z, Zhang S, Lin H, Gao C, Zhao J, et al. Methionine and Its Hydroxyl Analogues Improve Stem Cell Activity To Eliminate Deoxynivalenol-Induced Intestinal Injury by Reactivating Wnt/β-Catenin Signaling. J Agric Food Chem. 2019;67:11464-11473 pubmed publisher |
| Kinjo T, Ito M, Seki T, Fukuhara T, Bolati K, Arai H, et al. Prenatal exposure to valproic acid is associated with altered neurocognitive function and neurogenesis in the dentate gyrus of male offspring rats. Brain Res. 2019;1723:146403 pubmed publisher |
| Quach N, Kaur S, Eggert M, Ingram L, Ghosh D, Sheth S, et al. Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth. Sci Rep. 2019;9:11478 pubmed publisher |
| Gegen T, Zhu Y, Sun Q, Hou B. Role of interleukin-33 in the clinical pathogenesis of chronic apical periodontitis. J Int Med Res. 2019;47:3332-3343 pubmed publisher |
| Zhou J, Zhang S, Lin H, Gao C, Yan H, Wang X. Hydrolyzed wheat gluten alleviates deoxynivalenol-induced intestinal injury by promoting intestinal stem cell proliferation and differentiation via upregulation of Wnt/β-catenin signaling in mice. Food Chem Toxicol. 2019;131:110579 pubmed publisher |
| Smith P, Godde N, Rubio S, Tekeste M, Vladar E, Axelrod J, et al. VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland. Sci Rep. 2019;9:7079 pubmed publisher |
| Gao B, Deng R, Chai Y, Chen H, Hu B, Wang X, et al. Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration. J Clin Invest. 2019;129:2578-2594 pubmed publisher |
| Zhou J, Huang D, Qin Y, Li X, Gao C, Yan H, et al. mTORC1 signaling activation increases intestinal stem cell activity and promotes epithelial cell proliferation. J Cell Physiol. 2019;234:19028-19038 pubmed publisher |
| Bielli A, Scioli M, D Amico F, Tarquini C, Agostinelli S, Costanza G, et al. Cellular retinoic acid binding protein-II expression and its potential role in skin aging. Aging (Albany NY). 2019;11:1619-1632 pubmed publisher |
| Ibrahim M, Klement J, Lu C, Redd P, Xiao W, Yang D, et al. Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis. Cell Rep. 2018;25:3036-3046.e6 pubmed publisher |
| JENSEN T, Wanczyk H, Sharma I, Mitchell A, Sayej W, Finck C. Polyurethane scaffolds seeded with autologous cells can regenerate long esophageal gaps: An esophageal atresia treatment model. J Pediatr Surg. 2018;: pubmed publisher |
| Baek H, Kim S, Choi E, Kim J, Shin D, Park E, et al. Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation. Int J Biol Sci. 2018;14:1755-1768 pubmed publisher |
| D Andrea P, Sciancalepore M, Veltruská K, Lorenzon P, Bandiera A. Epidermal Growth Factor - based adhesion substrates elicit myoblast scattering, proliferation, differentiation and promote satellite cell myogenic activation. Biochim Biophys Acta Mol Cell Res. 2018;: pubmed publisher |
| Hou Q, Liu L, Dong Y, Wu J, Du L, Dong H, et al. Effects of Thymoquinone on radiation enteritis in mice. Sci Rep. 2018;8:15122 pubmed publisher |
| Li L, Guturi K, Gautreau B, Patel P, Saad A, Morii M, et al. Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis. J Clin Invest. 2018;128:4525-4542 pubmed publisher |
| Dower C, Bhat N, Gebru M, Chen L, Wills C, Miller B, et al. Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma. Mol Cancer Ther. 2018;17:2365-2376 pubmed publisher |
| SCHMITT M, Schewe M, Sacchetti A, Feijtel D, van de Geer W, Teeuwssen M, et al. Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling. Cell Rep. 2018;24:2312-2328.e7 pubmed publisher |
| Kamdar K, Johnson A, Chac D, Myers K, Kulur V, Truevillian K, et al. Innate Recognition of the Microbiota by TLR1 Promotes Epithelial Homeostasis and Prevents Chronic Inflammation. J Immunol. 2018;201:230-242 pubmed publisher |
| Tanaka T, Kelly M, Takei Y, Yamanouchi D. RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice. J Vasc Surg. 2018;68:48S-59S.e1 pubmed publisher |
| Tamosiuniene R, Manouvakhova O, Mésange P, Saito T, Qian J, Sanyal M, et al. Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension. Circ Res. 2018;122:1689-1702 pubmed publisher |
| Li Q, Alsaidan O, Ma Y, Kim S, Liu J, Albers T, et al. Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression. J Biol Chem. 2018;293:6434-6448 pubmed publisher |
| Gunji H, Kunimatsu R, Tsuka Y, Yoshimi Y, Sumi K, Awada T, et al. Effect of high-frequency near-infrared diode laser irradiation on periodontal tissues during experimental tooth movement in rats. Lasers Surg Med. 2018;: pubmed publisher |
| Huang R, Wang X, Zhou Y, Xiao Y. RANKL-induced M1 macrophages are involved in bone formation. Bone Res. 2017;5:17019 pubmed publisher |
| Li Y, Zhang C, Sheng Q, Bai H, Ding Y, Dou X. Mesenchymal stem cells rescue acute hepatic failure by polarizing M2 macrophages. World J Gastroenterol. 2017;23:7978-7988 pubmed publisher |
| Chen W, Pilling D, Gomer R. C-reactive protein (CRP) but not the related pentraxins serum amyloid P and PTX3 inhibits the proliferation and induces apoptosis of the leukemia cell line Mono Mac 6. BMC Immunol. 2017;18:47 pubmed publisher |
| Harrell J, Shroka T, Jacobsen B. Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer. Oncogenesis. 2017;6:396 pubmed publisher |
| Wang K, Jin Q, Ruan D, Yang Y, Liu Q, Wu H, et al. Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing. Genome Res. 2017;27:2061-2071 pubmed publisher |
| Li C, Chai Y, Wang L, Gao B, Chen H, Gao P, et al. Programmed cell senescence in skeleton during late puberty. Nat Commun. 2017;8:1312 pubmed publisher |
| Park S, Kim J, Jun H, Roh J, Lee H, Hong I. Stem Cell Secretome and Its Effect on Cellular Mechanisms Relevant to Wound Healing. Mol Ther. 2018;26:606-617 pubmed publisher |
| Amarnani D, Machuca Parra A, Wong L, Marko C, Stefater J, Stryjewski T, et al. Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017;58:3940-3949 pubmed publisher |
| Tan Q, Joshua A, Wang M, Bristow R, Wouters B, Allen C, et al. Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity. Cancer Chemother Pharmacol. 2017;79:959-969 pubmed publisher |
| Jayaraman S, Doucet M, Kominsky S. Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA. Oncotarget. 2017;8:6169-6178 pubmed publisher |
| Peng Y, Chen F, Ge J, Zhu J, Shi X, Li X, et al. miR-429 Inhibits Differentiation and Promotes Proliferation in Porcine Preadipocytes. Int J Mol Sci. 2016;17: pubmed |
| Maeda A, Chen Y, Bu J, Mujcic H, Wouters B, Dacosta R. In Vivo Imaging Reveals Significant Tumor Vascular Dysfunction and Increased Tumor Hypoxia-Inducible Factor-1? Expression Induced by High Single-Dose Irradiation in a Pancreatic Tumor Model. Int J Radiat Oncol Biol Phys. 2017;97:184-194 pubmed publisher |
| Zimmermann N, Thormann V, Hu B, Köhler A, Imai Matsushima A, Locht C, et al. Human isotype-dependent inhibitory antibody responses against Mycobacterium tuberculosis. EMBO Mol Med. 2016;8:1325-1339 pubmed publisher |
| Xiong J, Zhou M, Wang Y, Chen L, Xu W, Wang Y, et al. Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice. Sci Rep. 2016;6:34079 pubmed publisher |
| Huang S, Lien J, Kuo S, Huang T. DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling. Oncotarget. 2016;7:63124-63137 pubmed publisher |
| Röck K, Joosse S, Muller J, Heinisch N, Fuchs N, Meusch M, et al. Chronic UVB-irradiation actuates perpetuated dermal matrix remodeling in female mice: Protective role of estrogen. Sci Rep. 2016;6:30482 pubmed publisher |
| Lohse I, Rasowski J, Cao P, Pintilie M, Do T, Tsao M, et al. Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302. Oncotarget. 2016;7:33571-80 pubmed publisher |
| Fukuda T, Fukuchi T, Yagi S, Shiojiri N. Immunohistochemical analyses of cell cycle progression and gene expression of biliary epithelial cells during liver regeneration after partial hepatectomy of the mouse. Exp Anim. 2016;65:135-46 pubmed publisher |
| de la Puente P, Muz B, Gilson R, Azab F, Luderer M, King J, et al. 3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma. Biomaterials. 2015;73:70-84 pubmed publisher |
| Nakagawa Y, Muneta T, Kondo S, Mizuno M, Takakuda K, Ichinose S, et al. Synovial mesenchymal stem cells promote healing after meniscal repair in microminipigs. Osteoarthritis Cartilage. 2015;23:1007-17 pubmed publisher |
| Uegaki T, Taniguchi F, Nakamura K, Osaki M, Okada F, Yamamoto O, et al. Inhibitor of apoptosis proteins (IAPs) may be effective therapeutic targets for treating endometriosis. Hum Reprod. 2015;30:149-58 pubmed publisher |
| Hu P, Chung L, Berel D, Frierson H, Yang H, Liu C, et al. Convergent RANK- and c-Met-mediated signaling components predict survival of patients with prostate cancer: an interracial comparative study. PLoS ONE. 2013;8:e73081 pubmed publisher |
| Shin M, Matsuo K, Tada T, Fukushima H, Furuta H, Ozeki S, et al. The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells. Carcinogenesis. 2011;32:1634-40 pubmed publisher |
| Sandra F, Hendarmin L, Kukita T, Nakao Y, Nakamura N, Nakamura S. Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone. Oral Oncol. 2005;41:637-44 pubmed |
| Rubin J, Chung L, Fan X, Zhu L, Murphy T, Nanes M, et al. Prostate carcinoma cells that have resided in bone have an upregulated IGF-I axis. Prostate. 2004;58:41-9 pubmed |
| Niida S, Kawahara M, Ishizuka Y, Ikeda Y, Kondo T, Hibi T, et al. Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor. J Biol Chem. 2004;279:5752-6 pubmed |
| Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater A, et al. Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. Blood. 2001;98:2784-90 pubmed |
| Pearse R, Sordillo E, Yaccoby S, Wong B, Liau D, Colman N, et al. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A. 2001;98:11581-6 pubmed |
| Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, et al. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. J Immunol. 2001;166:3574-9 pubmed |
| Hsu H, Lacey D, Dunstan C, Solovyev I, Colombero A, Timms E, et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci U S A. 1999;96:3540-5 pubmed |
