| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; fig s4a
| Li M, Yang X, LU X, Dai N, Zhang S, Cheng Y, et al. APE1 deficiency promotes cellular senescence and premature aging features. Nucleic Acids Res. 2018;46:5664-5677 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig s5b
| Bisht K, Smith E, Tesmer V, Nandakumar J. Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc Natl Acad Sci U S A. 2016;113:13021-13026 pubmed |
- immunocytochemistry; human; fig 5a
| Shukla S, Schmidt J, Goldfarb K, Cech T, Parker R. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. Nat Struct Mol Biol. 2016;23:286-92 pubmed publisher |
- immunocytochemistry; human; fig s10
| Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher |
- immunocytochemistry; human
| Fujita T, Yuno M, Okuzaki D, Ohki R, Fujii H. Identification of non-coding RNAs associated with telomeres using a combination of enChIP and RNA sequencing. PLoS ONE. 2015;10:e0123387 pubmed publisher |
- immunocytochemistry; human
| Schertzer M, Jouravleva K, Perderiset M, Dingli F, Loew D, Le Guen T, et al. Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA. Nucleic Acids Res. 2015;43:1834-47 pubmed publisher |
- chromatin immunoprecipitation; human
- western blot; human
| Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D Angelo C, et al. A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds. Nucleic Acids Res. 2015;43:1759-69 pubmed publisher |
- immunocytochemistry; human
| Freund A, Zhong F, Venteicher A, Meng Z, Veenstra T, Frydman J, et al. Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Cell. 2014;159:1389-403 pubmed publisher |
- chromatin immunoprecipitation; human
| Kocak H, Ballew B, Bisht K, Eggebeen R, Hicks B, Suman S, et al. Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1. Genes Dev. 2014;28:2090-102 pubmed publisher |
| Acharya S, Kaul Z, Gocha A, Martinez A, Harris J, Parvin J, et al. Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells. PLoS ONE. 2014;9:e103819 pubmed publisher |
| Bai Y, Lathia J, Zhang P, Flavahan W, Rich J, Mattson M. Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells. Glia. 2014;62:1687-98 pubmed publisher |
| Edwards D, Orren D, Machwe A. Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2. Nucleic Acids Res. 2014;42:7748-61 pubmed publisher |
| Das U, Manna K, Sinha M, Datta S, Das D, Chakraborty A, et al. Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model. PLoS ONE. 2014;9:e97599 pubmed publisher |
- immunocytochemistry; human
| Ohishi T, Muramatsu Y, Yoshida H, Seimiya H. TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation. Mol Cell Biol. 2014;34:2464-78 pubmed publisher |
- immunocytochemistry; human
| Stimpson K, Sullivan L, Kuo M, Sullivan B. Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS ONE. 2014;9:e92432 pubmed publisher |
- immunoprecipitation; human
- western blot; human
| Popuri V, Hsu J, Khadka P, Horvath K, Liu Y, Croteau D, et al. Human RECQL1 participates in telomere maintenance. Nucleic Acids Res. 2014;42:5671-88 pubmed publisher |
- immunocytochemistry; human
| Nakashima M, Nandakumar J, Sullivan K, Espinosa J, Cech T. Inhibition of telomerase recruitment and cancer cell death. J Biol Chem. 2013;288:33171-80 pubmed publisher |
- immunocytochemistry; human
| Brugat T, Nguyen Khac F, Grelier A, Merle Béral H, Delic J. Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells. Blood. 2010;116:239-49 pubmed publisher |
| Bhattacharyya S, Keirsey J, Russell B, Kavecansky J, Lillard Wetherell K, Tahmaseb K, et al. Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates. J Biol Chem. 2009;284:14966-77 pubmed publisher |
- immunocytochemistry; human
| Huang F, Chang C, Lou P, Kuo I, Chien C, Chen C, et al. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells. Mol Cancer Res. 2008;6:955-64 pubmed publisher |
| Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H. Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation. Exp Cell Res. 2008;314:1115-24 pubmed publisher |
- immunocytochemistry; human
| Cristofari G, Adolf E, Reichenbach P, Sikora K, Terns R, Terns M, et al. Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell. 2007;27:882-9 pubmed |
- chromatin immunoprecipitation; human
- western blot; human
| Tahara H, Shin Ya K, Seimiya H, Yamada H, Tsuruo T, Ide T. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells. Oncogene. 2006;25:1955-66 pubmed |
- immunocytochemistry; deer
| Hartmann N, Scherthan H. Characterization of the telomere complex, TERF1 and TERF2 genes in muntjac species with fusion karyotypes. Exp Cell Res. 2005;306:64-74 pubmed |
- immunoprecipitation; human
- western blot; human
| Houghtaling B, Cuttonaro L, Chang W, Smith S. A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr Biol. 2004;14:1621-31 pubmed |
- immunocytochemistry; human
- western blot; human
| Kim S, Beausejour C, Davalos A, Kaminker P, Heo S, Campisi J. TIN2 mediates functions of TRF2 at human telomeres. J Biol Chem. 2004;279:43799-804 pubmed |
- immunocytochemistry; mouse
- western blot; mouse
| Fotiadou P, Henegariu O, Sweasy J. DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line. Cancer Res. 2004;64:3830-7 pubmed |
| Deng Z, Atanasiu C, Burg J, Broccoli D, Lieberman P. Telomere repeat binding factors TRF1, TRF2, and hRAP1 modulate replication of Epstein-Barr virus OriP. J Virol. 2003;77:11992-2001 pubmed |
| Stavropoulos D, Bradshaw P, Li X, Pasic I, Truong K, Ikura M, et al. The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis. Hum Mol Genet. 2002;11:3135-44 pubmed |
- immunocytochemistry; human
- western blot; human
| Cook B, Dynek J, Chang W, Shostak G, Smith S. Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol Cell Biol. 2002;22:332-42 pubmed |
- immunocytochemistry; human
| Johnson F, Marciniak R, McVey M, Stewart S, Hahn W, Guarente L. The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO J. 2001;20:905-13 pubmed |
- immunohistochemistry - paraffin section; human
| Scherthan H, Jerratsch M, Li B, Smith S, Hulten M, Lock T, et al. Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores. Mol Biol Cell. 2000;11:4189-203 pubmed |
| Zhang J, Zhang F, Porter K, Dakup P, Wang S, Robertson G, et al. Telomere dysfunction in Tert knockout mice delays BrafV600E -induced melanoma development. Int J Cancer. 2024;154:548-560 pubmed publisher |
| Wang Y, Zhu W, Jang Y, Sommers J, Yi G, Puligilla C, et al. The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loops. Nucleic Acids Res. 2023;51:12242-12260 pubmed publisher |
| Hou J, Yun Y, Jeon B, Baek J, Kim S. Ginsenoside F1-Mediated Telomere Preservation Delays Cellular Senescence. Int J Mol Sci. 2023;24: pubmed publisher |
| Kliszczak M, Moralli D, Jankowska J, Bryjka P, Subha Meem L, Goncalves T, et al. Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length. Front Cell Dev Biol. 2023;11:1175069 pubmed publisher |
| Jacome Burbano M, Robin J, Bauwens S, Martin M, Donati E, Mart xed nez L, et al. Non-canonical telomere protection role of FOXO3a of human skeletal muscle cells regulated by the TRF2-redox axis. Commun Biol. 2023;6:561 pubmed publisher |
| Eguchi A, Gonzalez A, Torres Bigio S, Koleckar K, Birnbaum F, Zhang J, et al. TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. Proc Natl Acad Sci U S A. 2023;120:e2209967120 pubmed publisher |
| Dinami R, Pompili L, Petti E, Porru M, D Angelo C, Di Vito S, et al. MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer. EMBO Mol Med. 2023;15:e16033 pubmed publisher |
| Mendez Bermudez A, Lototska L, Pousse M, Tessier F, Croce O, Latrick C, et al. Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence. Nucleic Acids Res. 2022;50:7493-7510 pubmed publisher |
| Zhang L, Geng X, Wang F, Tang J, Ichida Y, Sharma A, et al. 53BP1 regulates heterochromatin through liquid phase separation. Nat Commun. 2022;13:360 pubmed publisher |
| Yu E, Zahid S, Aloe S, Falck Pedersen E, Zhou X, Cheung N, et al. Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology. Commun Biol. 2021;4:1315 pubmed publisher |
| Mohanty B, Karam J, Howley B, Dalton A, Grelet S, Dincman T, et al. Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity. Life Sci Alliance. 2021;4: pubmed publisher |
| AZARM K, Bhardwaj A, Kim E, Smith S. Persistent telomere cohesion protects aged cells from premature senescence. Nat Commun. 2020;11:3321 pubmed publisher |
| Chen Y, Sheu J, Sun C, Huang T, Lin Y, Yip H. MicroRNA-214 modulates the senescence of vascular smooth muscle cells in carotid artery stenosis. Mol Med. 2020;26:46 pubmed publisher |
| Episkopou H, Diman A, Claude E, Viceconte N, Decottignies A. TSPYL5 Depletion Induces Specific Death of ALT Cells through USP7-Dependent Proteasomal Degradation of POT1. Mol Cell. 2019;: pubmed publisher |
| Kim J, Sun C, Tran A, Chin P, Ruiz P, Wang K, et al. The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening. Nat Struct Mol Biol. 2019;26:213-219 pubmed publisher |
| Kong X, Cruz G, Trinh S, Zhu X, Berns M, Yokomori K. Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair. J Cell Sci. 2018;131: pubmed publisher |
| Fujiwara C, Muramatsu Y, Nishii M, Tokunaka K, Tahara H, Ueno M, et al. Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells. Sci Rep. 2018;8:14827 pubmed publisher |
| Bernal A, Moltó Abad M, Dominguez D, Tusell L. Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells. Oncotarget. 2018;9:27151-27170 pubmed publisher |
| Panneer Selvam S, Roth B, Nganga R, Kim J, Cooley M, Helke K, et al. Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. J Biol Chem. 2018;293:9784-9800 pubmed publisher |
| Mendez Bermudez A, Lototska L, Bauwens S, Giraud Panis M, Croce O, Jamet K, et al. Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2. Mol Cell. 2018;70:449-461.e5 pubmed publisher |
| Ma Y, Wang M, Li W, Zhang Z, Zhang X, Wu G, et al. Live Visualization of HIV-1 Proviral DNA Using a Dual-Color-Labeled CRISPR System. Anal Chem. 2017;: pubmed publisher |
| Jahn A, Rane G, Paszkowski Rogacz M, Sayols S, Bluhm A, Han C, et al. ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator. EMBO Rep. 2017;18:929-946 pubmed publisher |
| Jeitany M, Bakhos Douaihy D, Silvestre D, Pineda J, Ugolin N, Moussa A, et al. Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance. Oncotarget. 2017;8:26269-26280 pubmed publisher |
| Fouquerel E, Lormand J, Bose A, Lee H, Kim G, Li J, et al. Oxidative guanine base damage regulates human telomerase activity. Nat Struct Mol Biol. 2016;23:1092-1100 pubmed publisher |
| Konishi A, Izumi T, Shimizu S. TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends. J Biol Chem. 2016;291:20798-810 pubmed publisher |
| Picco V, Coste I, Giraud Panis M, Renno T, Gilson E, Pages G. ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2. Oncotarget. 2016;7:46615-46627 pubmed publisher |
| Kim Y, Kim K, Lee S, Hong S, Moon J, Yoon E, et al. Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma. Theranostics. 2016;6:357-68 pubmed publisher |
| Hasegawa D, Okabe S, Okamoto K, Nakano I, Shin ya K, Seimiya H. G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells. Biochem Biophys Res Commun. 2016;471:75-81 pubmed publisher |
| Altieri P, Barisione C, Lazzarini E, Garuti A, Bezante G, Canepa M, et al. Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes. J Am Heart Assoc. 2016;5: pubmed publisher |
| Xi L, Schmidt J, Zaug A, Ascarrunz D, Cech T. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015;16:231 pubmed publisher |
| Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed publisher |
| Burla R, Carcuro M, Raffa G, Galati A, Raimondo D, Rizzo A, et al. AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance. PLoS Genet. 2015;11:e1005167 pubmed publisher |
| Panneer Selvam S, De Palma R, Oaks J, Oleinik N, Peterson Y, Stahelin R, et al. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal. 2015;8:ra58 pubmed publisher |
| Münch S, Weidtkamp Peters S, Klement K, Grigaravicius P, Monajembashi S, Salomoni P, et al. The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence. Mol Cell Biol. 2014;34:1733-46 pubmed publisher |
| Queisser A, Heeg S, Thaler M, von Werder A, Opitz O. Inhibition of telomerase induces alternative lengthening of telomeres during human esophageal carcinogenesis. Cancer Genet. 2013;206:374-86 pubmed publisher |
| Saha B, Zitnik G, Johnson S, Nguyen Q, Risques R, Martin G, et al. DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations. Front Genet. 2013;4:129 pubmed publisher |
| Kamranvar S, Chen X, Masucci M. Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus. Oncogene. 2013;32:5522-30 pubmed publisher |
| Zhou J, Richardson M, Reddy V, Menon M, Barrack E, Reddy G, et al. Structural and functional association of androgen receptor with telomeres in prostate cancer cells. Aging (Albany NY). 2013;5:3-17 pubmed |
| Gocha A, Nuovo G, Iwenofu O, Groden J. Human sarcomas are mosaic for telomerase-dependent and telomerase-independent telomere maintenance mechanisms: implications for telomere-based therapies. Am J Pathol. 2013;182:41-8 pubmed publisher |
| Nandakumar J, Bell C, Weidenfeld I, Zaug A, Leinwand L, Cech T. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012;492:285-9 pubmed publisher |
| Orlotti N, Cimino Reale G, Borghini E, Pennati M, Sissi C, Perrone F, et al. Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage. Autophagy. 2012;8:1185-96 pubmed publisher |
| Suram A, Kaplunov J, Patel P, Ruan H, Cerutti A, Boccardi V, et al. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J. 2012;31:2839-51 pubmed publisher |
| Galati A, Magdinier F, Colasanti V, Bauwens S, Pinte S, Ricordy R, et al. TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner. PLoS ONE. 2012;7:e34386 pubmed publisher |
| Bhanot M, Smith S. TIN2 stability is regulated by the E3 ligase Siah2. Mol Cell Biol. 2012;32:376-84 pubmed publisher |
| Ghosh A, Rossi M, Singh D, Dunn C, Ramamoorthy M, Croteau D, et al. RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance. J Biol Chem. 2012;287:196-209 pubmed publisher |
| Abreu E, Terns R, Terns M. Visualization of human telomerase localization by fluorescence microscopy techniques. Methods Mol Biol. 2011;735:125-37 pubmed publisher |
| Kamranvar S, Masucci M. The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress. Leukemia. 2011;25:1017-25 pubmed publisher |
| Rodier F, Muñoz D, Teachenor R, Chu V, Le O, Bhaumik D, et al. DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion. J Cell Sci. 2011;124:68-81 pubmed publisher |
| Stimpson K, Song I, Jauch A, Holtgreve Grez H, Hayden K, Bridger J, et al. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. PLoS Genet. 2010;6: pubmed publisher |
| Benson E, Lee S, Aaronson S. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. J Cell Sci. 2010;123:2605-12 pubmed publisher |
| Abreu E, Aritonovska E, Reichenbach P, Cristofari G, Culp B, Terns R, et al. TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo. Mol Cell Biol. 2010;30:2971-82 pubmed publisher |
| Yoshitake K, Aoyagi H, Fujiwara H. Creation of a novel telomere-cutting endonuclease based on the EN domain of telomere-specific non-long terminal repeat retrotransposon, TRAS1. Mob DNA. 2010;1:13 pubmed publisher |
| Tempera I, Deng Z, Atanasiu C, Chen C, D Erme M, Lieberman P. Regulation of Epstein-Barr virus OriP replication by poly(ADP-ribose) polymerase 1. J Virol. 2010;84:4988-97 pubmed publisher |
| Kim S, Richardson M, Chinnakannu K, Bai V, Menon M, Barrack E, et al. Androgen receptor interacts with telomeric proteins in prostate cancer cells. J Biol Chem. 2010;285:10472-6 pubmed publisher |
| Cesare A, Kaul Z, Cohen S, Napier C, Pickett H, Neumann A, et al. Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions. Nat Struct Mol Biol. 2009;16:1244-51 pubmed publisher |
| Brouwer A, Schimmel J, Wiegant J, Vertegaal A, Tanke H, Dirks R. Telomeric DNA mediates de novo PML body formation. Mol Biol Cell. 2009;20:4804-15 pubmed publisher |
| Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, Londono Vallejo A. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc Natl Acad Sci U S A. 2009;106:15726-31 pubmed publisher |
| Caslini C, Connelly J, Serna A, Broccoli D, Hess J. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol. 2009;29:4519-26 pubmed publisher |
| Huda N, Tanaka H, Mendonca M, Gilley D. DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair. Mol Cell Biol. 2009;29:3597-604 pubmed publisher |
| Tatsumi Y, Ezura K, Yoshida K, Yugawa T, Narisawa Saito M, Kiyono T, et al. Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres. Genes Cells. 2008;13:1045-59 pubmed publisher |
| Kim S, Davalos A, Heo S, Rodier F, Zou Y, Beausejour C, et al. Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes. J Cell Biol. 2008;181:447-60 pubmed publisher |
| Zhang Y, Zhang Z, Miao Z, Ding J. The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine. Mol Pharmacol. 2008;73:824-32 pubmed |
| Jiang W, Zhong Z, Henson J, Reddel R. Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference. Oncogene. 2007;26:4635-47 pubmed |
| Barcaroli D, Dinsdale D, Neale M, Bongiorno Borbone L, Ranalli M, Munarriz E, et al. FLASH is an essential component of Cajal bodies. Proc Natl Acad Sci U S A. 2006;103:14802-7 pubmed |
| Barcaroli D, Bongiorno Borbone L, Terrinoni A, Hofmann T, Rossi M, Knight R, et al. FLASH is required for histone transcription and S-phase progression. Proc Natl Acad Sci U S A. 2006;103:14808-12 pubmed |
| Raz V, Carlotti F, Vermolen B, van der Poel E, Sloos W, Knaän Shanzer S, et al. Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells. J Cell Sci. 2006;119:4247-56 pubmed |
| Bellon M, Datta A, Brown M, Pouliquen J, Couppie P, Kazanji M, et al. Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia. Int J Cancer. 2006;119:2090-7 pubmed |
| Biroccio A, Rizzo A, Elli R, Koering C, Belleville A, Benassi B, et al. TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells. Eur J Cancer. 2006;42:1881-8 pubmed |
| Luciani J, Depetris D, Usson Y, Metzler Guillemain C, Mignon Ravix C, Mitchell M, et al. PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase. J Cell Sci. 2006;119:2518-31 pubmed |
| Freibaum B, Counter C. hSnm1B is a novel telomere-associated protein. J Biol Chem. 2006;281:15033-6 pubmed |
| Tanaka H, Mendonca M, Bradshaw P, Hoelz D, Malkas L, Meyn M, et al. DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. Proc Natl Acad Sci U S A. 2005;102:15539-44 pubmed |
| Johnson J, Varkonyi R, Schwalm J, Cragle R, Klein Szanto A, Patchefsky A, et al. Multiple mechanisms of telomere maintenance exist in liposarcomas. Clin Cancer Res. 2005;11:5347-55 pubmed |
| Kaminker P, Plachot C, Kim S, Chung P, Crippen D, Petersen O, et al. Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2. J Cell Sci. 2005;118:1321-30 pubmed |
| Nijjar T, Bassett E, Garbe J, Takenaka Y, Stampfer M, Gilley D, et al. Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells. Oncogene. 2005;24:3369-76 pubmed |
| Bradshaw P, Stavropoulos D, Meyn M. Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage. Nat Genet. 2005;37:193-7 pubmed |
| Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T. Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics. Cancer Cell. 2005;7:25-37 pubmed |
| Ahn B, Harrigan J, Indig F, Wilson D, Bohr V. Regulation of WRN helicase activity in human base excision repair. J Biol Chem. 2004;279:53465-74 pubmed |
| Seimiya H, Muramatsu Y, Smith S, Tsuruo T. Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation. Mol Cell Biol. 2004;24:1944-55 pubmed |
| Opresko P, Von Kobbe C, Laine J, Harrigan J, Hickson I, Bohr V. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J Biol Chem. 2002;277:41110-9 pubmed |
| Deng Z, Lezina L, Chen C, Shtivelband S, So W, Lieberman P. Telomeric proteins regulate episomal maintenance of Epstein-Barr virus origin of plasmid replication. Mol Cell. 2002;9:493-503 pubmed |
| Okabe J, Eguchi A, Masago A, Hayakawa T, Nakanishi M. TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells. Hum Mol Genet. 2000;9:2639-50 pubmed |
