product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
5-HT7 Antibody - BSA Free
catalog :
NB100-56352
quantity :
0.1 mg (also 0.025 mg)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
Novus Biologicals product webpage
citations: 11
Reference
Yang J, Gao F, Yang X, Liang F, Yang Z, Chen J, et al. The 5-HT7 receptors in the VLO contribute to the development of morphine-induced behavioral sensitization in rats. Neurochem Int. 2023;168:105566 pubmed publisher
Okada M, Fukuyama K, Motomura E. Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine. Int J Mol Sci. 2022;23: pubmed publisher
Fukuyama K, Motomura E, Okada M. Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems. Int J Mol Sci. 2022;23: pubmed publisher
Fukuyama K, Motomura E, Shiroyama T, Okada M. Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gain. Biomed Pharmacother. 2022;148:112750 pubmed publisher
Chaudhary P, Guragain D, Chang J, Kim J. TPH1 and 5-HT7 Receptor Overexpression Leading to Gemcitabine-Resistance Requires Non-Canonical Permissive Action of EZH2 in Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2021;13: pubmed publisher
Shiroyama T, Fukuyama K, Okada M. Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. Int J Mol Sci. 2021;22: pubmed publisher
Okada M, Matsumoto R, Yamamoto Y, Fukuyama K. Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. Int J Mol Sci. 2021;22: pubmed publisher
Tempio A, Niso M, Laera L, Trisolini L, Favia M, Ciranna L, et al. Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT7 Receptor. Int J Mol Sci. 2020;21: pubmed publisher
Volpicelli F, Speranza L, Pulcrano S, de Gregorio R, Crispino M, de Sanctis C, et al. The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology. Mol Neurobiol. 2019;: pubmed publisher
Ito M, Komai K, Mise Omata S, Iizuka Koga M, Noguchi Y, Kondo T, et al. Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Nature. 2019;565:246-250 pubmed publisher
Wixey J, Reinebrant H, Chand K, Buller K. Disruption to the 5-HT7 Receptor Following Hypoxia-Ischemia in the Immature Rodent Brain. Neurochem Res. 2018;43:711-720 pubmed publisher
product information
master code :
NB100-56352
SKU :
NB100-56352
product name :
5-HT7 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The 5-HT7 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to 5-HT7. This antibody reacts with canine,human,mouse,rat. The 5-HT7 Antibody - BSA Free has been validated for the following applications: Western Blot,Simple Western,Flow Cytometry,Immunocytochemistry/ Immunofluorescence.
target :
5-HT7
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 13-28 of the rat 5-HT7R (AAA42134.1).
isotype :
IgG
purity :
Protein G purified
species :
Canine,Human,Mouse,Rat
specificity :
The 5HT7 antibody recognizes all described 5HT7 receptor splice variants
theoretical molecular weight :
54 kDa
gene symbol :
HTR7
Antibody validation :
Biological Validation
accessionNumbers :
P32305
applications :
Simple Western,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence
USD :
399 USD
alt names :
5-HT-7, 5-HT75-hydroxytryptamine receptor 7, 5-HT-X, 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled), serotonin 5-HT-7 receptor, Serotonin receptor 7
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.