This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mouse Monoclonal TLR4 Antibody (76B357.1) [FITC]
catalog :
NB100-55951
quantity :
0.1 ml
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
76B357.1
reactivity :
human, mouse, rat
application :
flow cytometry, western blot knockout validation
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:200; loading ...; fig 6c
  • western blot knockout validation; human; 1:500; loading ...; fig 6c
McCarthy G, Bridges C, Blednov Y, Harris R. CNS cell-type localization and LPS response of TLR signaling pathways. F1000Res. 2017;6:1144 pubmed publisher
Link A, Selejan S, Maack C, Lenz M, Bohm M. Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock. Crit Care. 2008;12:R159 pubmed publisher
Worku M, Morris A. Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils. J Dairy Sci. 2009;92:3185-93 pubmed publisher
Hafez M, Hayes K, Goldrick M, Grencis R, Roberts I. The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in ep. Infect Immun. 2010;78:2153-62 pubmed publisher
Nowicki M, Kosacka J, Serke H, Bluher M, Spanel Borowski K. Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome. J Neurosci Res. 2012;90:122-31 pubmed publisher
Allam J, Peng W, Appel T, Wenghoefer M, Niederhagen B, Bieber T, et al. Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells. J Allergy Clin Immunol. 2008;121:368-374.e1 pubmed
Johnston M, Wang A, Catarino M, Ball L, Phan V, MacDonald J, et al. Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice. Infect Immun. 2010;78:1364-75 pubmed publisher
Jazaeri F, Tavangar S, Ghazi Khansari M, Khorramizadeh M, Mani A, Dehpour A. Cirrhosis is associated with development of tolerance to cardiac chronotropic effect of endotoxin in rats. Liver Int. 2013;33:368-74 pubmed publisher
Janardhanam S, Prakasam S, Swaminathan V, Kodumudi K, Zunt S, Srinivasan M. Differential expression of TLR-2 and TLR-4 in the epithelial cells in oral lichen planus. Arch Oral Biol. 2012;57:495-502 pubmed publisher
Green T, Santos M, Ejaeidi A, Craft B, Lewis R, Cruse J. Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells. Exp Mol Pathol. 2014;97:44-8 pubmed publisher
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed publisher
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed publisher
Lunardi C, Bason C, Dolcino M, Navone R, Simone R, Saverino D, et al. Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's disease. J Intern Med. 2009;265:250-65 pubmed publisher
Semar S, Klotz M, Letiembre M, Van Ginneken C, Braun A, Jost V, et al. Changes of the enteric nervous system in amyloid-? protein precursor transgenic mice correlate with disease progression. J Alzheimers Dis. 2013;36:7-20 pubmed publisher
Zheng Y, Yang M, Rong T, Yuan X, Ma Y, Wang Z, et al. CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer. World J Gastroenterol. 2012;18:2253-61 pubmed publisher
Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, et al. In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Med. 2006;3:e358 pubmed
Wu Y, Lu J, Antony S, Juhasz A, Liu H, Jiang G, et al. Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-? and lipopolysaccharide in human pancreatic cancer cell lines. J Immunol. 2013;190:1859-72 pubmed publisher
Hsiao C, Kao Y, Huang S, Chuang J. Toll-like receptor-4 agonist inhibits motility and invasion of hepatoblastoma HepG2 cells in vitro. Pediatr Blood Cancer. 2013;60:248-53 pubmed publisher
McCulloch L, Brown K, Mabbott N. Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function. Immunology. 2013;138:246-57 pubmed publisher
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed publisher
Voss E, Skuljec J, Gudi V, Skripuletz T, Pul R, Trebst C, et al. Characterisation of microglia during de- and remyelination: can they create a repair promoting environment?. Neurobiol Dis. 2012;45:519-28 pubmed publisher
Liu Y, Fatheree N, Mangalat N, Rhoads J. Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-?B signaling in the intestine. Am J Physiol Gastrointest Liver Physiol. 2012;302:G608-17 pubmed publisher
Brandau S, Jakob M, Hemeda H, Bruderek K, Janeschik S, Bootz F, et al. Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge. J Leukoc Biol. 2010;88:1005-15 pubmed publisher
product information
Catalog Number :
NB100-55951
Product Name :
Mouse Monoclonal TLR4 Antibody (76B357.1) [FITC]
List Price :
369 USD
product type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Buffer :
50mM Sodium Borate
Clonality :
Monoclonal
Clone :
76B357.1
Conjugate :
FITC
Application Summary :
Flow (Cell Surface), Flow Cytometry
Host :
Mouse
Immunogen :
This antibody was developed against a portion of amino acids 100-200 of human TLR4 (NP_612564).
Isotype :
IgG2b Kappa
Preservative :
0.05% Sodium Azide
Purity :
Protein G purified
CrossReactivity :
Human, Mouse, Rat
Specificity :
The amino acid sequence used has 100% identity in human, chimp, baboon, chinese hamster, and rat; 93% identity in bovine and pig; 85% identity in sheep and 78% identity in cat, horse and mouse.
Storage :
Store at 4C in the dark.
Swissprot Human :
O00206
Uses :
Flow (Intracellular) use reported in literature (See Cohen et al, 2008); Immunofluorescence (See Nowicki et al, 2009); IHC-F (Nowicki et al, 2012); Flow (cell surface) use reported in scientific literature (PMID 23796194) Use in Flow cell surface reported in scientific literature (PMID 24836676)
Research Area :
Immunology, Innate Immunity, Toll Like Receptors
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.