product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RPA2 [p Ser33] Antibody - BSA Free
catalog :
NB100-544
quantity :
100 ul
price :
529 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry
more info or order :
Novus Biologicals product webpage
citations: 15
Reference
Tang J, Weiser N, Wang G, Chowdhry S, Curtis E, Zhao Y, et al. Enhancing transcription-replication conflict targets ecDNA-positive cancers. Nature. 2024;635:210-218 pubmed publisher
Lee H, Niida H, Sung S, Lee J. Haplotype-resolved de novo assembly revealed unique characteristics of alternative lengthening of telomeres in mouse embryonic stem cells. Nucleic Acids Res. 2024;52:12456-12474 pubmed publisher
Yeo X, Sundararajan V, Wu Z, Phua Z, Ho Y, Peh K, et al. The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer. Commun Biol. 2023;6:660 pubmed publisher
Rasti G, Becker M, Vazquez B, Espinosa Alcantud M, Fern xe1 ndez Duran I, G xe1 mez Garc xed a A, et al. SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex. Nucleic Acids Res. 2023;51:6754-6769 pubmed publisher
Vaitsiankova A, Burdova K, Sobol M, Gautam A, Benada O, Hanzlikova H, et al. PARP inhibition impedes the maturation of nascent DNA strands during DNA replication. Nat Struct Mol Biol. 2022;29:329-338 pubmed publisher
Miyauchi T, Suzuki S, Takeda M, Peh J, Aiba M, Natsuga K, et al. Altered replication stress response due to CARD14 mutations promotes recombination-induced revertant mosaicism. Am J Hum Genet. 2021;108:1026-1039 pubmed publisher
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell D, Lu W, et al. Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution. Cancer Discov. 2021;: pubmed publisher
Song L, Tang Z, Peng C, Yang Y, Guo C, Wang D, et al. Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium. BMC Cancer. 2020;20:1020 pubmed publisher
Ma L, Bian X, Lin W. The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer. J Exp Clin Cancer Res. 2020;39:219 pubmed publisher
Sanij E, Hannan K, Xuan J, Yan S, Ahern J, Trigos A, et al. CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer. Nat Commun. 2020;11:2641 pubmed publisher
Merchut Maya J, Maya Mendoza A, Fornara O, Rahbar A, Bröchner C, Sehested A, et al. Cancer cell stemness, responses to experimental genotoxic treatments, cytomegalovirus protein expression and DNA replication stress in pediatric medulloblastomas. Cell Cycle. 2020;19:727-741 pubmed publisher
Clairmont C, Sarangi P, Ponnienselvan K, Galli L, Csete I, Moreau L, et al. TRIP13 regulates DNA repair pathway choice through REV7 conformational change. Nat Cell Biol. 2020;22:87-96 pubmed publisher
Maya Mendoza A, Moudry P, Merchut Maya J, Lee M, Strauss R, Bartek J. High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018;559:279-284 pubmed publisher
Tang Z, Yang J, Wang X, Zeng M, Wang J, Wang A, et al. Active DNA end processing in micronuclei of ovarian cancer cells. BMC Cancer. 2018;18:426 pubmed publisher
Her J, Ray C, Altshuler J, Zheng H, Bunting S. 53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress. Mol Cell Biol. 2018;38: pubmed publisher
product information
master code :
NB100-544
SKU :
NB100-544
product name :
RPA2 [p Ser33] Antibody - BSA Free
unit size :
100 ul
description :
The RPA2 [p Ser33] Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RPA2. This antibody reacts with human,mouse. The RPA2 [p Ser33] Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western.
target :
RPA2
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Immunogen was a phosphorylated synthetic peptide, which represented a portion of human replication protein A2, 32 kDa surrounding phosphorylated serine that corresponded to position 33 using the numbering given in entry NP_002937.1 (GeneID 6118).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
specificity :
NB100-544 is specific for human RPA-32 pSer33 protein
theoretical molecular weight :
32 kDa
gene symbol :
RPA2
Antibody validation :
Biological Validation
accessionNumbers :
P15927
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western
USD :
529 USD
alt names :
REPA2, Replication factor A protein 2, replication protein A 32 kDa subunit, Replication protein A 34 kDa subunit, replication protein A2 (32kD), replication protein A2, 32kDa, RF-A protein 2, RP-A p32, RP-A p34, RPA32, RPA34
storage :
Store at 4C. Do not freeze.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.