product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GFAP Antibody
catalog :
NB100-53809
quantity :
0.1 mg
price :
409 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 18
Reference
Duan M, Ru X, Zhou J, Li Y, Guo P, Kang W, et al. Endothelial EGLN3-PKM2 signaling induces the formation of acute astrocytic barrier to alleviate immune cell infiltration after subarachnoid hemorrhage. Fluids Barriers CNS. 2024;21:42 pubmed publisher
Islam R, Choudhary H, Mehta H, Zhang F, Jovin T, Hanafy K. Development of a 3D Brain Model to Study Sex-Specific Neuroinflammation After Hemorrhagic Stroke. Transl Stroke Res. 2024;: pubmed publisher
Partiot E, Gorda B, Lutz W, Lebrun S, Khalfi P, Mora S, et al. Organotypic culture of human brain explants as a preclinical model for AI-driven antiviral studies. EMBO Mol Med. 2024;16:1004-1026 pubmed publisher
Colvett I, Gilmore A, Guzman S, Ledreux A, Quintero J, Ginjupally D, et al. Recipient Reaction and Composition of Autologous Sural Nerve Tissue Grafts into the Human Brain. J Clin Med. 2023;12: pubmed publisher
Schreib C, Jarvis M, Terlier T, Goell J, Mukherjee S, Doerfert M, et al. Lipid Deposition Profiles Influence Foreign Body Responses. Adv Mater. 2023;35:e2205709 pubmed publisher
Kim J, de Haro M, Al Ramahi I, Garaicoechea L, Jeong H, Sonn J, et al. Evolutionarily conserved regulators of tau identify targets for new therapies. Neuron. 2023;111:824-838.e7 pubmed publisher
Zhou J, Guo P, Duan M, Li J, Ru X, Li L, et al. EphA4/EphrinB2 signaling mediates pericyte-induced transient glia limitans formation as a secondary protective barrier after subarachnoid hemorrhage in mice. Exp Neurol. 2023;360:114293 pubmed publisher
Zhu X, Schrader J, Irizarry B, Smith S, Van Nostrand W. Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Biomedicines. 2022;10: pubmed publisher
Liu X, Tang S, Liu S, Zeng J, Chen Z, Liu C, et al. Deficiency of astrocyte CysLT1R ameliorates depression-like behaviors in mice by modulating glutamate synaptic transmission. Neurobiol Dis. 2022;175:105922 pubmed publisher
Kofoed R, Noseworthy K, Wu K, Sivadas S, Stanek L, Elmer B, et al. The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites. Mol Ther Methods Clin Dev. 2022;27:167-184 pubmed publisher
Hogestyn J, Salois G, Xie L, Apa C, Youngyunpipatkul J, Pr xf6 schel C, et al. Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells. Mol Cell Neurosci. 2022;123:103770 pubmed publisher
Silburt J, Aubert I. MORPHIOUS: an unsupervised machine learning workflow to detect the activation of microglia and astrocytes. J Neuroinflammation. 2022;19:24 pubmed publisher
Elahi A, Emerson J, Rudlong J, Keillor J, Salois G, Visca A, et al. Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury. Cells. 2021;10: pubmed publisher
Kofoed R, Heinen S, Silburt J, Dubey S, Dibia C, Maes M, et al. Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP.B to the brain in a mouse model of amyloidosis. Mol Ther Methods Clin Dev. 2021;23:390-405 pubmed publisher
Shen H, Weltha L, Cook J, Gesese R, Omi W, Baer S, et al. Sarcosine Suppresses Epileptogenesis in Rats With Effects on Hippocampal DNA Methylation. Front Mol Neurosci. 2020;13:97 pubmed publisher
Lau A, So R, Lau H, Sang J, Ruiz Riquelme A, Fleck S, et al. α-Synuclein strains target distinct brain regions and cell types. Nat Neurosci. 2020;23:21-31 pubmed publisher
Weber Adrian D, Kofoed R, Chan J, Silburt J, Noroozian Z, Kügler S, et al. Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease. Theranostics. 2019;9:8127-8137 pubmed publisher
Xhima K, Nabbouh F, Hynynen K, Aubert I, Tandon A. Noninvasive delivery of an α-synuclein gene silencing vector with magnetic resonance-guided focused ultrasound. Mov Disord. 2018;33:1567-1579 pubmed publisher
product information
master code :
NB100-53809
SKU :
NB100-53809
product name :
GFAP Antibody
unit size :
0.1 mg
description :
The GFAP Antibody from Novus is a goat polyclonal antibody to GFAP. This antibody reacts with human,mouse,rat. The GFAP Antibody has been validated for the following applications: IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunohistochemistry Whole-Mount,Immunohistochemistry,Peptide ELISA.
target :
GFAP
category :
Primary Antibodies
buffer :
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
clonality :
Polyclonal
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Goat
immunogen :
This GFAP Antibody was developed against a peptide with sequence C-DGEVIKESKQEHKD corresponding to C-Terminus according to NP_002046.1.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
specificity :
GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood, despite the number of studies using it as a cell marker
theoretical molecular weight :
50 kDa
gene symbol :
GFAP
accessionNumbers :
NP_002046.1
applications :
IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunohistochemistry Whole-Mount,Immunohistochemistry,Peptide ELISA
USD :
409 USD
alt names :
ALXDRD, FLJ45472, GFAP, GFAP astrocytes, glial fibrillary acidic protein
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.