NOD2 Antibody (2D9) - BSA Free | Novus Biologicals NB100-524 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

NOD2 Antibody (2D9) - BSA Free

catalog :

NB100-524

quantity :

0.1 ml (also 0.025 ml)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D9

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 25

Reference
Thakker P, Ariana A, Hajjar S, Cai D, Rijal D, Sad S. XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively. PLoS Pathog. 2023;19:e1011455 pubmed publisher
Li X, Liu S, Jin L, Ma Y, Liu T. NOD2 inhibits the proliferation of esophageal adenocarcinoma cells through autophagy. J Cancer Res Clin Oncol. 2023;149:639-652 pubmed publisher
Hardman C, Chen Y, Salimi M, Nahler J, Corridoni D, Jagielowicz M, et al. IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent. Sci Immunol. 2021;6: pubmed publisher
Huaman M, Qualls J, Jose S, Schmidt S, Moussa A, Kuhel D, et al. Mycobacterium bovis Bacille-Calmette-Guérin Infection Aggravates Atherosclerosis. Front Immunol. 2020;11:607957 pubmed publisher
Mai E, Percopo C, Limkar A, Sek A, Ma M, Rosenberg H. Respiratory Epithelial Cells Respond to Lactobacillus plantarum but Provide No Cross-Protection against Virus-Induced Inflammation. Viruses. 2020;13: pubmed publisher
Zhang L, Zhang B, Wei M, Xu Z, Kong W, Deng K, et al. TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis. Int J Oncol. 2020;56:1225-1239 pubmed publisher
Tikka C, Manthari R, Ommati M, Niu R, Sun Z, Zhang J, et al. Immune disruption occurs through altered gut microbiome and NOD2 in arsenic induced mice: Correlation with colon cancer markers. Chemosphere. 2020;246:125791 pubmed publisher
Valdez Miramontes C, Trejo Martínez L, Torres Juarez F, Rodríguez Carlos A, Marin Luévano S, de Haro Acosta J, et al. Nicotine modulates molecules of the innate immune response in epithelial cells and macrophages during infection with M. tuberculosis. Clin Exp Immunol. 2020;199:230-243 pubmed publisher
Mey L, Jung M, Roos F, Blaheta R, Hegele A, Kinscherf R, et al. NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells. J Cancer Res Clin Oncol. 2019;145:1405-1416 pubmed publisher
Lipinski S, Petersen B, Barann M, Piecyk A, Tran F, Mayr G, et al. Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2. Cold Spring Harb Mol Case Stud. 2019;5: pubmed publisher
Singh K, Han K, Tilve S, Wu K, Geller H, Sack M. Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation. Glia. 2018;66:2427-2437 pubmed publisher
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, et al. The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation. J Oral Pathol Med. 2019;48:87-95 pubmed publisher
Subramanian K, Bergman P, Henriques Normark B. Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils. J Innate Immun. 2017;9:375-386 pubmed publisher
Kapoor A, Forman M, Arav Boger R. Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. PLoS ONE. 2014;9:e92704 pubmed publisher
Lipinski S, Grabe N, Jacobs G, Billmann Born S, Till A, Häsler R, et al. RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition. Proc Natl Acad Sci U S A. 2012;109:21426-31 pubmed publisher
Marischen L, Wesch D, Oberg H, Rosenstiel P, Trad A, Shomali M, et al. Functional expression of NOD2 in freshly isolated human peripheral blood ?? T cells. Scand J Immunol. 2011;74:126-34 pubmed publisher
Billmann Born S, Till A, Arlt A, Lipinski S, Sina C, Latiano A, et al. Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC. J Immunol. 2011;186:4027-38 pubmed publisher
von Kampen O, Lipinski S, Till A, Martin S, Nietfeld W, Lehrach H, et al. Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling. J Biol Chem. 2010;285:19921-6 pubmed publisher
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med. 2010;16:90-7 pubmed publisher
Lipinski S, Till A, Sina C, Arlt A, Grasberger H, Schreiber S, et al. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J Cell Sci. 2009;122:3522-30 pubmed publisher
Chauhan V, Sterka D, Furr S, Young A, Marriott I. NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens. Glia. 2009;57:414-23 pubmed publisher
Kim T, Payne U, Zhang X, Iwanaga Y, Davey M, Rosenbaum J, et al. Altered host:pathogen interactions conferred by the Blau syndrome mutation of NOD2. Rheumatol Int. 2007;27:257-62 pubmed
McDonald C, Chen F, Ollendorff V, Ogura Y, Marchetto S, Lecine P, et al. A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. J Biol Chem. 2005;280:40301-9 pubmed
Ogura Y, Lala S, Xin W, Smith E, Dowds T, Chen F, et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut. 2003;52:1591-7 pubmed
Lala S, Ogura Y, Osborne C, Hor S, Bromfield A, Davies S, et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology. 2003;125:47-57 pubmed

product information

master code :

NB100-524

SKU :

NB100-524

product name :

NOD2 Antibody (2D9) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The NOD2 Antibody (2D9) - BSA Free from Novus is a mouse monoclonal antibody to NOD2. This antibody reacts with human,mouse. The NOD2 Antibody (2D9) - BSA Free has been validated for the following applications: Immunohistochemistry,IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Frozen,Flow (Intracellular).

target :

NOD2

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

2D9

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant human NOD2 protein corresponding to residues 28-301. [UniProt# Q9HC29]

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse

theoretical molecular weight :

110 kDa

gene symbol :

NOD2

applications :

IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Frozen,Flow (Intracellular)

USD :

459 USD

alt names :

BLAU, CARD15caspase recruitment domain protein 15, caspase recruitment domain family, member 15, Caspase recruitment domain-containing protein 15, CDACUG, CLR16.3, IBD1NLR family, CARD domain containing 2, Inflammatory bowel disease protein 1, NLRC2, NOD-like receptor C2, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain containing 2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domaincontaining 2, nucleotide-binding oligomerization domain-containing protein 2, PSORAS1NOD2B

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage