product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal PINK1 Antibody
catalog :
NB100-493R
quantity :
0.1 ml
price :
319.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
DyLight 550
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
Catalog Number :
NB100-493R
Product Name :
Rabbit Polyclonal PINK1 Antibody
List Price :
319.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
EC 2.7.11.1, FLJ27236, PARK6, Parkinson disease (autosomal recessive) 6, protein kinase BRPK, PTEN induced putative kinase 1, PTEN-induced putative kinase protein 1, serine/threonine-protein kinase PINK1, mitochondrial, BRPK
Background :
Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids. Malfunctions in this contribute to many human cancers. PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers. It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Conjugate :
DyLight 550
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
An N-terminal region synthetic peptide made to the human PINK1 protein sequence (between residues 1-50). [UniProt# Q9BXM7]
Localization :
Mitochondrion
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human and mouse. Rat reactivity reported in scientific literature (PMID: 24411077)
Storage :
Store at 4C in the dark.
Swissprot Human :
Q9BXM7
TMW :
60 kDa
Uses :
This PINK1 antibody is useful for Western blot, where a band is seen ~60 kDa.
Research Area :
Alzheimers Research, DNA Repair, Lipid and Metabolism, Mitochondrial Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Protein Kinase, Signal Transduction
more info or order :
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.