XPC Antibody (3.26) - Azide and BSA Free | Novus Biologicals NB100-477 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

XPC Antibody (3.26) - Azide and BSA Free

catalog :

NB100-477

quantity :

100 ul

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3.26

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 24

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 2	Fast O, Gentry B, Strouth L, Niece M, BECKFORD F, Shell S. Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC. Biosci Rep. 2019;: pubmed publisher
	Hameed J S F, Devarajan A, M S D, Bhattacharyya A, Shirude M, Dutta D, et al. PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair. BMC Cancer. 2023;23:399 pubmed publisher
	Schaich M, Schnable B, Kumar N, Roginskaya V, Jakielski R, Urban R, et al. Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE). Nucleic Acids Res. 2023;51:e39 pubmed publisher
	Dai W, Wu A, Li Y, Yu G, Yan X. XPA Enhances Temozolomide Resistance of Glioblastoma Cells by Promoting Nucleotide Excision Repair. Cell Transplant. 2022;31:9636897221092778 pubmed publisher
	Sakai W, Yuasa Sunagawa M, Kusakabe M, Kishimoto A, Matsui T, Kaneko Y, et al. Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repair. Sci Rep. 2020;10:19704 pubmed publisher
	Holland S, Ramer L, McMahon S, Denk F, Ramer M. An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle. Eneuro. 2019;6: pubmed publisher
	Bianchetti E, Bates S, Carroll S, Siegelin M, Roth K. Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors. Sci Rep. 2018;8:17390 pubmed publisher
	Mousseau M, Burma N, Lee K, Leduc Pessah H, Kwok C, Reid A, et al. Microglial pannexin-1 channel activation is a spinal determinant of joint pain. Sci Adv. 2018;4:eaas9846 pubmed publisher
	Beresova L, Vesela E, Chamrad I, Voller J, Yamada M, Furst T, et al. Role of DNA Repair Factor Xeroderma Pigmentosum Protein Group C in Response to Replication Stress As Revealed by DNA Fragile Site Affinity Chromatography and Quantitative Proteomics. J Proteome Res. 2016;15:4505-4517 pubmed
	Mohni K, Kavanaugh G, Cortez D. ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Cancer Res. 2014;74:2835-45 pubmed publisher
	Berra C, de Oliveira C, Garcia C, Rocha C, Lerner L, Lima L, et al. Nucleotide excision repair activity on DNA damage induced by photoactivated methylene blue. Free Radic Biol Med. 2013;61:343-56 pubmed publisher
	Kothandapani A, Gopalakrishnan K, Kahali B, Reisman D, Patrick S. Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity. Exp Cell Res. 2012;318:1973-86 pubmed publisher
	Muenyi C, States V, Masters J, Fan T, Helm C, States J. Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC). J Ovarian Res. 2011;4:9 pubmed publisher
	de Feraudy S, Ridd K, Richards L, Kwok P, Revet I, Oh D, et al. The DNA damage-binding protein XPC is a frequent target for inactivation in squamous cell carcinomas. Am J Pathol. 2010;177:555-62 pubmed publisher
	Acu I, Liu T, Suino Powell K, Mooney S, D Assoro A, Rowland N, et al. Coordination of centrosome homeostasis and DNA repair is intact in MCF-7 and disrupted in MDA-MB 231 breast cancer cells. Cancer Res. 2010;70:3320-8 pubmed publisher
	Takedachi A, Saijo M, Tanaka K. DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA. Mol Cell Biol. 2010;30:2708-23 pubmed publisher
	Rezvani H, Mahfouf W, Ali N, Chemin C, Ged C, Kim A, et al. Hypoxia-inducible factor-1alpha regulates the expression of nucleotide excision repair proteins in keratinocytes. Nucleic Acids Res. 2010;38:797-809 pubmed publisher
	Yan T, Seo Y, Kinsella T. Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells. Clin Cancer Res. 2009;15:6912-20 pubmed publisher
	Klein U, Nigg E. SUMO-dependent regulation of centrin-2. J Cell Sci. 2009;122:3312-21 pubmed publisher
	Wang Y, Liu X, Matsuda A, Plunkett W. Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair. Cancer Res. 2008;68:3881-9 pubmed publisher
	Ferguson Yates B, Li H, Dong T, Hsiao J, Oh D. Impaired repair of cyclobutane pyrimidine dimers in human keratinocytes deficient in p53 and p63. Carcinogenesis. 2008;29:70-5 pubmed
	Laposa R, Huang E, Cleaver J. Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice. Proc Natl Acad Sci U S A. 2007;104:1389-94 pubmed
	Lovejoy C, Lock K, Yenamandra A, Cortez D. DDB1 maintains genome integrity through regulation of Cdt1. Mol Cell Biol. 2006;26:7977-90 pubmed
	Ferguson B, Oh D. Proficient global nucleotide excision repair in human keratinocytes but not in fibroblasts deficient in p53. Cancer Res. 2005;65:8723-9 pubmed

product information

master code :

NB100-477

SKU :

NB100-477

product name :

XPC Antibody (3.26) - Azide and BSA Free

unit size :

100 ul

description :

The XPC Antibody (3.26) - Azide and BSA Free from Novus is a mouse monoclonal antibody to XPC. This antibody reacts with human,mouse. The XPC Antibody (3.26) - Azide and BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Western Blot,Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

XPC

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

3.26

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant XPC purified from E. coli

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse

theoretical molecular weight :

123 kDa

gene symbol :

XPC

accessionNumbers :

Q01831

applications :

Western Blot,Immunofluorescence,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

459 USD

alt names :

complementation group C, p125, RAD4, Xeroderma pigmentosum group C-complementing protein, xeroderma pigmentosum, complementation group C, XP3, XPCCDNA repair protein complementing XP-C cells

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage