WRN Antibody - BSA Free | Novus Biologicals NB100-471 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

WRN Antibody - BSA Free

catalog :

NB100-471

quantity :

100 ul

price :

479 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 1c western blot; human; loading ...; fig 3c	Liu B, Yi J, Yang X, Liu L, Lou X, Zhang Z, et al. MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner. Oncogene. 2019;38:2501-2515 pubmed publisher
	Maresca C, Dello Stritto A, D Angelo C, Petti E, Rizzo A, Vertecchi E, et al. PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment. Commun Biol. 2023;6:234 pubmed publisher
	Datta A, Biswas K, Sommers J, Thompson H, Awate S, Nicolae C, et al. WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells. Nat Commun. 2021;12:6561 pubmed publisher
	Strassheim D, Karoor V, Nijmeh H, Weston P, Lapel M, Schaack J, et al. c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells. Cells. 2020;9: pubmed publisher
	Gericke A, Mann C, Zadeh J, Musayeva A, Wolff I, Wang M, et al. Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles. Oxid Med Cell Longev. 2019;2019:9736047 pubmed publisher
	Zadeh J, Ruemmler R, Hartmann E, Ziebart A, Ludwig M, Patzak A, et al. Responses of retinal arterioles and ciliary arteries in pigs with acute respiratory distress syndrome (ARDS). Exp Eye Res. 2019;184:152-161 pubmed publisher
	Serganova I, Cohen I, Vemuri K, Shindo M, Maeda M, Mane M, et al. LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response. PLoS ONE. 2018;13:e0203965 pubmed publisher
	Hayashi K, Tasaka T, Kondo T, Ishikawa Y, Goto M, Matsuhashi Y, et al. Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome. Intern Med. 2019;58:109-113 pubmed publisher
	Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. Br J Cancer. 2017;116:479-488 pubmed publisher
	Knudsen E, Balaji U, Freinkman E, McCue P, Witkiewicz A. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. Oncotarget. 2016;7:78396-78411 pubmed publisher
	De Bruycker S, Vangestel C, Van den Wyngaert T, Wyffels L, Wouters A, Pauwels P, et al. Baseline [(18)F]FMISO Î¼PET as a Predictive Biomarker for Response to HIF-1Î± Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model. Mol Imaging Biol. 2016;18:606-16 pubmed publisher
	Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed publisher

product information

master code :

NB100-471

SKU :

NB100-471

product name :

WRN Antibody - BSA Free

unit size :

100 ul

description :

The WRN Antibody - BSA Free from Novus is a rabbit polyclonal antibody to WRN. This antibody reacts with human. The WRN Antibody - BSA Free has been validated for the following applications: Simple Western,Chemotaxis,IF/IHC,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation.

target :

WRN

category :

Primary Antibodies

buffer :

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residues 400 and 450 of human Werner Syndrome Helicase using the numbering given in SwissProt entry Q14191 (GeneID 7486).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human

gene symbol :

WRN

Antibody validation :

Independent Anitbodies

accessionNumbers :

Q14191

applications :

Simple Western,Chemotaxis,IF/IHC,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation

USD :

479 USD

alt names :

DKFZp686C2056, DNA helicase, RecQ-like type 3, EC 3.1, EC 3.6.1, EC 3.6.4.12, Exonuclease WRN, RecQ protein-like 2, RecQ3, RECQ3RECQL3, RECQL2Werner syndrome ATP-dependent helicase, Werner syndrome, Werner syndrome, RecQ helicase-like

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage