| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; rhesus macaque; loading ...; fig 7a, 7b
- western blot; human; loading ...; fig 5a
| Sil S, Singh S, Chemparathy D, Chivero E, Gordon L, Buch S. Astrocytes & Astrocyte derived Extracellular Vesicles in Morphine Induced Amyloidopathy: Implications for Cognitive Deficits in Opiate Abusers. Aging Dis. 2021;12:1389-1408 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3a
| Kim Y, Lee M, Gu H, Kim J, Jeong S, Yeo S, et al. HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Dis Model Mech. 2018;11: pubmed publisher |
- western blot; mouse; loading ...; fig 5b
| Gardner P, Liyanage S, Cristante E, Sampson R, Dick A, Ali R, et al. Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye. Sci Rep. 2017;7:40830 pubmed publisher |
- western blot; mouse; fig 2
| Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed publisher |
- western blot; mouse; loading ...; fig s7a
| Kobayashi H, Liu Q, Binns T, Urrutia A, Davidoff O, Kapitsinou P, et al. Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. J Clin Invest. 2016;126:1926-38 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig 3
| Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed publisher |
| Nishizawa H, Funasaki S, Ma W, Kubota Y, Watanabe K, Arima Y, et al. HIF1α Plays a Crucial Role in the Development of TFE3-Rearranged Renal Cell Carcinoma by Orchestrating a Metabolic Shift Toward Fatty Acid Synthesis. Genes Cells. 2025;30:e13195 pubmed publisher |
| Kang G, Kim Y, Oh H, Jo H, Bok S, Jeon Y, et al. Hypoxia-inducible factor-1α-deficient adipose-tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein-1. Lab Anim Res. 2024;40:37 pubmed publisher |
| Li J, Wang M, Ruan J, Lyu Y, Weng Y, Brindangnanam P, et al. A transcription-independent role for HIF-1α in modulating microprocessor assembly. Nucleic Acids Res. 2024;52:11806-11821 pubmed publisher |
| Rose K, Zorlu M, Fassini A, Lee H, Cai W, Xue X, et al. Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers. NPJ Parkinsons Dis. 2024;10:152 pubmed publisher |
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| Prieto Fernández E, Egia Mendikute L, Vila Vecilla L, Bosch A, Barreira Manrique A, Lee S, et al. Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate. Emerg Microbes Infect. 2021;10:1065-1076 pubmed publisher |
| Laquatra C, Sanchez Martin C, Dinarello A, Cannino G, Minervini G, Moroni E, et al. HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia. Cell Death Dis. 2021;12:434 pubmed publisher |
| van Kuijk K, Demandt J, Perales Paton J, Theelen T, Kuppe C, Marsch E, et al. DEFICIENCY OF MYELOID PHD PROTEINS AGGRAVATES ATHEROGENESIS VIA MACROPHAGE APOPTOSIS AND PARACRINE FIBROTIC SIGNALING: Atherogenic effects of myeloid PHD knockdown. Cardiovasc Res. 2021;: pubmed publisher |
| Rashed F, Stoica A, Macdonald D, El Saidi H, Ricardo C, Bhatt B, et al. Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins. Redox Biol. 2021;41:101905 pubmed publisher |
| Noonan M, Ni P, Agoro R, Sacks S, Swallow E, Wheeler J, et al. The HIF-PHI BAY 85-3934 (Molidustat) Improves Anemia and Is Associated With Reduced Levels of Circulating FGF23 in a CKD Mouse Model. J Bone Miner Res. 2021;36:1117-1130 pubmed publisher |
| Ito E, Sato Y, Kobayashi T, Nakamura S, Kaneko Y, Soma T, et al. Treatment with an active vitamin D analogue blocks hypothalamic dysfunction-induced bone loss in mice. Biochem Biophys Res Commun. 2021;542:48-53 pubmed publisher |
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| Armando F, Godizzi F, Razzuoli E, Leonardi F, Angelone M, Corradi A, et al. Epithelial to Mesenchymal Transition (EMT) in a Laryngeal Squamous Cell Carcinoma of a Horse: Future Perspectives. Animals (Basel). 2020;10: pubmed publisher |
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| Gauthier L, Saati M, Bensalah Pigeon H, Ben M Barek K, Gitton Quent O, Bertrand R, et al. The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation. Sci Rep. 2020;10:18742 pubmed publisher |
| Prieto Fernández E, Egia Mendikute L, Bosch A, García Del Río A, Jimenez Lasheras B, Antoñana Vildosola A, et al. Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment. Front Immunol. 2020;11:586977 pubmed publisher |
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| Nugrahaningrum D, Marcelina O, Liu C, Wu S, Kasim V. Dapagliflozin Promotes Neovascularization by Improving Paracrine Function of Skeletal Muscle Cells in Diabetic Hindlimb Ischemia Mice Through PHD2/HIF-1α Axis. Front Pharmacol. 2020;11:1104 pubmed publisher |
| Vaughan M, Wallace M, Handzlik M, Chan A, Metallo C, Lamia K. Cryptochromes Suppress HIF1α in Muscles. iScience. 2020;23:101338 pubmed publisher |
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| Kim K, Kim Y, Choi K, Lee M, Lee S, Im W, et al. Downregulated miR-18b-5p triggers apoptosis by inhibition of calcium signaling and neuronal cell differentiation in transgenic SOD1 (G93A) mice and SOD1 (G17S and G86S) ALS patients. Transl Neurodegener. 2020;9:23 pubmed publisher |
| Ghosh P, Guo Y, Ashrafi A, Chen J, Dey S, Zhong S, et al. Oxygen-Enhanced Optoacoustic Tomography Reveals the Effectiveness of Targeting Heme and Oxidative Phosphorylation at Normalizing Tumor Vascular Oxygenation. Cancer Res. 2020;80:3542-3555 pubmed publisher |
| Hu L, Chen X, Qiu S, Yang J, Liu H, Zhang J, et al. Intra-Pancreatic Insulin Nourishes Cancer Cells: Do Insulin-Receptor Antagonists such as PGG and EGCG Play a Role?. Am J Chin Med. 2020;48:1005-1019 pubmed publisher |
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| Gupta S, Sharp R, Hofferek C, Kuai L, Dorn G, Wang J, et al. NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells. Cell Rep. 2019;29:1862-1877.e7 pubmed publisher |
| Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, et al. The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. Sci Signal. 2019;12: pubmed publisher |
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| Chen Y, Zhao B, Zhu Y, Zhao H, Ma C. HIF-1-VEGF-Notch mediates angiogenesis in temporomandibular joint osteoarthritis. Am J Transl Res. 2019;11:2969-2982 pubmed |
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| Igari K, Kelly M, Yamanouchi D. Digoxin Attenuates Receptor Activation of NF-κB Ligand-Induced Osteoclastogenesis in Macrophages. J Vasc Res. 2019;:1-10 pubmed publisher |
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| Valencia Cervantes J, Huerta Yepez S, Aquino Jarquin G, Rodriguez Enriquez S, Martinez Fong D, Arias Montaño J, et al. Hypoxia increases chemoresistance in human medulloblastoma DAOY cells via hypoxia‑inducible factor 1α‑mediated downregulation of the CYP2B6, CYP3A4 and CYP3A5 enzymes and inhibition of cell proliferation. Oncol Rep. 2019;41:178-190 pubmed publisher |
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| Li B, Zhu Y, Sun Q, Yu C, Chen L, Tian Y, et al. Reversal of the Warburg effect with DCA in PDGF‑treated human PASMC is potentiated by pyruvate dehydrogenase kinase‑1 inhibition mediated through blocking Akt/GSK‑3β signalling. Int J Mol Med. 2018;42:1391-1400 pubmed publisher |
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