product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PBR Antibody
catalog :
NB100-41398
quantity :
0.1 mg
price :
409 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
clone name :
AE-1/AE-3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Reference
Nutma E, Gebro E, Marzin M, van der Valk P, Matthews P, Owen D, et al. Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain. Glia. 2021;69:2447-2458 pubmed publisher
Chang C, Chiu C, Lin M, Wu H, Yu T, Wang P, et al. GMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression. EJNMMI Res. 2021;11:26 pubmed publisher
Cohen A, Li J, Hight M, McKinley E, Fu A, Payne A, et al. TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions. Clin Cancer Res. 2020;26:5914-5925 pubmed publisher
Fukushima K, Satoh T, Sugihara F, Sato Y, Okamoto T, Mitsui Y, et al. Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis. Immunity. 2020;52:542-556.e13 pubmed publisher
Hieu Tran V, Park H, Park J, Kwon Y, Kang S, Ho Jung J, et al. Synthesis and evaluation of novel potent TSPO PET ligands with 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamide. Bioorg Med Chem. 2019;27:4069-4080 pubmed publisher
Oppel F, Tao T, Shi H, Ross K, Zimmerman M, He S, et al. Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies. PLoS Genet. 2019;15:e1008039 pubmed publisher
Wan J, Block S, Scribano C, Thiry R, Esbona K, Audhya A, et al. Mad1 destabilizes p53 by preventing PML from sequestering MDM2. Nat Commun. 2019;10:1540 pubmed publisher
JENSEN T, Wanczyk H, Sharma I, Mitchell A, Sayej W, Finck C. Polyurethane scaffolds seeded with autologous cells can regenerate long esophageal gaps: An esophageal atresia treatment model. J Pediatr Surg. 2018;: pubmed publisher
Buck J, McKinley E, Fu A, Abel T, Thompson R, Chambless L, et al. Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study. PLoS ONE. 2015;10:e0141659 pubmed publisher
Zhou T, Frabutt D, Moremen K, Zheng Y. ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway. J Biol Chem. 2015;290:22184-92 pubmed publisher
product information
master code :
NB100-41398
SKU :
NB100-41398
product name :
PBR Antibody
unit size :
0.1 mg
description :
The PBR Antibody from Novus is a goat polyclonal antibody to PBR. This antibody reacts with human,mouse,rat. The PBR Antibody has been validated for the following applications: Immunohistochemistry,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Peptide ELISA.
target :
PBR
category :
Primary Antibodies
buffer :
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
clonality :
Polyclonal
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Goat
immunogen :
Peptide with sequence C-RDNHGWRGGRRLPE corresponding to C-Terminus according to NP_000705.2.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
specificity :
This antibody is expected to recognise one isoform (NP_000705
theoretical molecular weight :
18.8 kDa
gene symbol :
TSPO
accessionNumbers :
P30536
applications :
Immunohistochemistry,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Peptide ELISA
USD :
409 USD
alt names :
benzodiazepine peripheral binding site, BZRPDBI, IBP, MBRPBS, mDRC, Mitochondrial benzodiazepine receptor, PBRBPBS, PBRS, peripheral benzodiazepine receptor, Peripheral-type benzodiazepine receptor, pk18, PKBSbenzodiazapine receptor (peripheral), PTBR, translocator protein, translocator protein (18kDa)
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.