DOT1L Antibody | Novus Biologicals NB100-40845 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DOT1L Antibody

catalog :

NB100-40845

quantity :

0.1 ml

price :

459 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

OTI1A6

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 13

Reference
Zhao W, Sun F, Zhang L, Ouyang J. NEAT1 variant 1 weakens the genome-wide effect of miR-3122 on blocking H3K79me3 in bladder cancer. Aging (Albany NY). 2022;14:4819-4826 pubmed publisher
Yang M, Yu H, Yu X, Liang S, Hu Y, Luo Y, et al. Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells. Cell Stem Cell. 2022;29:400-418.e13 pubmed publisher
Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, et al. HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Cancer Cell. 2019;36:645-659.e8 pubmed publisher
Lv L, Li Q, Chen S, Zhang X, Tao X, Tang X, et al. miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L. Exp Cell Res. 2019;385:111597 pubmed publisher
Liu B, Yang L, Zhu X, Li H, Zhu P, Wu J, et al. Yeats4 drives ILC lineage commitment via activation of Lmo4 transcription. J Exp Med. 2019;216:2653-2668 pubmed publisher
Penolazzi L, Bonaccorsi G, Gafa R, Ravaioli N, Gabriele D, Bosi C, et al. SLUG/HIF1-α/miR-221 regulatory circuit in endometrial cancer. Gene. 2019;711:143938 pubmed publisher
Szablewski V, Bret C, Kassambara A, Devin J, Cartron G, Costes Martineau V, et al. An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy. Oncotarget. 2018;9:19079-19099 pubmed publisher
Stepan A, Ciurea R, Drăgoescu P, Florescu M, Stepan M. Immunoexpression of transcription factors in urothelial bladder carcinomas. Rom J Morphol Embryol. 2017;58:863-869 pubmed
Loeser H, Waldschmidt D, Kuetting F, Heydt C, Zander T, Plum P, et al. Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target. Mol Clin Oncol. 2017;6:639-642 pubmed publisher
Lakhdar R, Drost E, MacNee W, Bastos R, Rabinovich R. 2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls. Respir Res. 2017;18:81 pubmed publisher
Munteanu C, Pirici D, Stepan A, Camen A, Margaritescu C. Maxillary calcifying epithelial odontogenic tumor with sinus and buccal vestibule extension: a case report and immunohistochemical study. Diagn Pathol. 2016;11:134 pubmed
Gilan O, Lam E, Becher I, Lugo D, Cannizzaro E, Joberty G, et al. Functional interdependence of BRD4 and DOT1L in MLL leukemia. Nat Struct Mol Biol. 2016;23:673-81 pubmed publisher
Cappellesso R, Marioni G, Crescenzi M, Giacomelli L, Guzzardo V, Mussato A, et al. The prognostic role of the epithelial-mesenchymal transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma. Histopathology. 2015;67:491-500 pubmed publisher

product information

master code :

NB100-40845

SKU :

NB100-40845

product name :

DOT1L Antibody

unit size :

0.1 ml

description :

The DOT1L Antibody from Novus is a rabbit polyclonal antibody to DOT1L. This antibody reacts with human,mouse. The DOT1L Antibody has been validated for the following applications: Chemotaxis,Chip Cytometry,IF/IHC,Western Blot,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing.

target :

DOT1L

category :

Primary Antibodies

buffer :

TBS and 0.1% BSA

clonality :

Polyclonal

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residue1000 and 1050 of human DOT1-Like using the numbering given in entry NP_115871.1 (GeneID 84444).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse

theoretical molecular weight :

185 kDa

gene symbol :

DOT1L

Antibody validation :

Independent Anitbodies

accessionNumbers :

Q8TEK3

applications :

Chemotaxis,Chip Cytometry,IF/IHC,Western Blot,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing

USD :

459 USD

alt names :

DOT1-like protein, DOT1-like, histone H3 methyltransferase (S. cerevisiae), EC 2.1.1.43, H3-K79-HMTase, KIAA1814DKFZp586P1823, KMT4H3 lysine-79 specific, Lysine N-methyltransferase 4

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage