TOP2B Antibody | Novus Biologicals NB100-40842 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TOP2B Antibody

catalog :

NB100-40842

quantity :

0.1 ml

price :

459 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq

more info or order :

Novus Biologicals product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
ChIP-Seq; mouse; ; loading ...; fig 4a chromatin immunoprecipitation; mouse; ; loading ...; fig 7d	Alvarez Quilón A, Terron Bautista J, Delgado Sainz I, Serrano Benítez A, Romero Granados R, Martínez García P, et al. Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency. Nat Commun. 2020;11:910 pubmed publisher
	Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou Clocher A, Tsamardinos I, et al. XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes. Sci Adv. 2023;9:eadi2095 pubmed publisher
	Najnin R, Al Mahmud M, Rahman M, Takeda S, Sasanuma H, Tanaka H, et al. ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen. Cell Rep. 2023;42:111909 pubmed publisher
	Mart xed nez Garc xed a P, Garc xed a Torres M, Divina F, Terr xf3 n Bautista J, Delgado Sainz I, G xf3 mez Vela F, et al. Genome-wide prediction of topoisomerase IIβ binding by architectural factors and chromatin accessibility. PLoS Comput Biol. 2021;17:e1007814 pubmed publisher
	Sciascia N, Wu W, Zong D, Sun Y, Wong N, John S, et al. Suppressing proteasome mediated processing of Topoisomerase II DNA-protein complexes preserves genome integrity. elife. 2020;9: pubmed publisher
	Webster M, Fane M, Alicea G, Basu S, Kossenkov A, Marino G, et al. Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma. Mol Cell. 2020;77:633-644.e5 pubmed publisher
	Vogel F, Bordag N, Zügner E, Trajkovic Arsic M, Chauvistré H, Shannan B, et al. Targeting the H3K4 demethylase KDM5B reprograms the metabolome and phenotype of melanoma cells. J Invest Dermatol. 2019;: pubmed publisher
	Shannan B, Matschke J, Chauvistré H, Vogel F, Klein D, Meier F, et al. Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma. Eur J Cancer. 2019;109:137-153 pubmed publisher
	Boyle S, Fedele C, Corbin V, Wybacz E, Szeto P, Lewin J, et al. CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity. Cancer Res. 2016;76:3965-77 pubmed publisher
	Hedayati M, Haffner M, Coulter J, Raval R, Zhang Y, Zhou H, et al. Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation. Clin Cancer Res. 2016;22:3310-3319 pubmed publisher
	Lu W, Liu S, Li B, Xie Y, Adhiambo C, Yang Q, et al. SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination. Oncotarget. 2015;6:771-88 pubmed

product information

master code :

NB100-40842

SKU :

NB100-40842

product name :

TOP2B Antibody

unit size :

0.1 ml

description :

The TOP2B Antibody from Novus is a rabbit polyclonal antibody to TOP2B. This antibody reacts with human,mouse. The TOP2B Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

TOP2B

category :

Primary Antibodies

buffer :

TBS and 0.1% BSA

clonality :

Polyclonal

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residue 1570 and the C-terminus (residue 1621) of human DNA Topoisomerase II Beta using the numbering given in entry NP_001059.2 (GeneID 7155).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse

theoretical molecular weight :

183 kDa

gene symbol :

TOP2B

Antibody validation :

Independent Anitbodies

accessionNumbers :

Q02880

applications :

Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

459 USD

alt names :

antigen MLAA-44, DNA topoisomerase 2-beta, DNA topoisomerase II beta, DNA topoisomerase II, 180 kD, DNA topoisomerase II, beta isozyme, EC 5.99.1.3, top2beta, TOPIIB, topo II beta, topoisomerase (DNA) II beta (180kD), topoisomerase (DNA) II beta 180kDa, topoisomerase II beta, topoisomerase IIb, U937 associated antigen

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage