product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SLC31A1/CTR1 Antibody - BSA Free
catalog :
NB100-402
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
9C8
reactivity :
human, mouse, rat, dogs, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 45
Reference
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Zhang X, Jiang Q, Su Y, Bu L, Sun Z, Wu X, et al. AMPK phosphorylates and stabilises copper transporter 1 to synergise metformin and copper chelator for breast cancer therapy. Br J Cancer. 2023;128:1452-1465 pubmed publisher
Shin V, Liu M, Siu J, Kwong A, Chu K. Inhibition of EP2 receptor suppresses tumor growth and chemoresistance of gastric cancer. Am J Cancer Res. 2022;12:4680-4692 pubmed
Choi H, Oh D, Kim M, Cai L, Lee J, Kim E, et al. Copper deficiency affects the developmental competence of porcine oocytes matured in vitro. Front Cell Dev Biol. 2022;10:993030 pubmed publisher
Saifi M, Godugu C. Copper chelation therapy inhibits renal fibrosis by modulating copper transport proteins. Biofactors. 2022;48:934-945 pubmed publisher
Aloysius Dhivya M, Sulochana K, Bharathi Devi S. High glucose induced inflammation is inhibited by copper chelation via rescuing mitochondrial fusion protein 2 in retinal pigment epithelial cells. Cell Signal. 2022;92:110244 pubmed publisher
Liu L, Du D, Zheng W, Zhang Y. Age-dependent decline of copper clearance at the blood-cerebrospinal fluid barrier. Neurotoxicology. 2022;88:44-56 pubmed publisher
Guo J, Cheng J, Zheng N, Zhang X, Dai X, Zhang L, et al. Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner. Adv Sci (Weinh). 2021;8:e2004303 pubmed publisher
Schoonover K, Kennedy W, Roberts R. Cortical copper transporter expression in schizophrenia: interactions of risk gene dysbindin-1. J Neural Transm (Vienna). 2021;128:701-709 pubmed publisher
Tsai T, Lai Y, Hw Chen H, Su W. Overcoming Radiation Resistance by Iron-Platinum Metal Alloy Nanoparticles in Human Copper Transport 1-Overexpressing Cancer Cells via Mitochondrial Disturbance. Int J Nanomedicine. 2021;16:2071-2085 pubmed publisher
Schoonover K, Farmer C, Morgan C, Sinha V, Odom L, Roberts R. Abnormalities in the copper transporter CTR1 in postmortem hippocampus in schizophrenia: A subregion and laminar analysis. Schizophr Res. 2021;228:60-73 pubmed publisher
Schoonover K, Roberts R. Markers of copper transport in the cingulum bundle in schizophrenia. Schizophr Res. 2021;228:124-133 pubmed publisher
Yu Z, Mersaoui S, Guitton Sert L, Coulombe Y, Song J, Masson J, et al. DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions. NAR Cancer. 2020;2:zcaa028 pubmed publisher
Iannelli F, Zotti A, Roca M, Grumetti L, Lombardi R, Moccia T, et al. Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance. Front Cell Dev Biol. 2020;8:732 pubmed publisher
Aubert L, Nandagopal N, Steinhart Z, Lavoie G, Nourreddine S, Berman J, et al. Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nat Commun. 2020;11:3701 pubmed publisher
Herranen A, Ikäheimo K, Lankinen T, Pakarinen E, Fritzsch B, Saarma M, et al. Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss. Cell Death Dis. 2020;11:100 pubmed publisher
Morrell A, Tripet B, Eilers B, Tegman M, Thompson D, Copie V, et al. Copper modulates sex-specific fructose hepatoxicity in nonalcoholic fatty liver disease (NALFD) Wistar rat models. J Nutr Biochem. 2020;78:108316 pubmed publisher
P xe9 r xe8 s E, Toutain J, Paty L, Divoux D, Ibaziz xe8 ne M, Guillouet S, et al. 64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study. EJNMMI Res. 2019;9:114 pubmed publisher
Timberlake Ii M, Roy B, Dwivedi Y. A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus. Mol Neurobiol. 2019;: pubmed publisher
Kim J, Kim B, Kim D, Jeong Y, Jeong S, Na Y, et al. Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer. Cancers (Basel). 2019;11: pubmed publisher
Yong L, Ma Y, Liang C, He G, Zhao Z, Yang C, et al. Oleandrin sensitizes human osteosarcoma cells to cisplatin by preventing degradation of the copper transporter 1. Phytother Res. 2019;33:1837-1850 pubmed publisher
Nakada E, Bhakta N, Korwin Mihavics B, Kumar A, Chamberlain N, Bruno S, et al. Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers. JCI Insight. 2019;4: pubmed publisher
Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, et al. FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex. EMBO Rep. 2019;20: pubmed publisher
Nakandakari S, Muñoz V, Kuga G, Gaspar R, Sant Ana M, Pavan I, et al. Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice. Brain Behav Immun. 2019;79:284-293 pubmed publisher
Ishihara K, Kawashita E, Shimizu R, Nagasawa K, Yasui H, Sago H, et al. Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome. Free Radic Biol Med. 2019;134:248-259 pubmed publisher
Delbrel E, Soumare A, Naguez A, Label R, Bernard O, Bruhat A, et al. HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis. Sci Rep. 2018;8:17939 pubmed publisher
Siegert A, Garcia Díaz Barriga G, Esteve Codina A, Navas Madroñal M, Gorbenko del Blanco D, Alberch J, et al. A FBN1 3'UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome. Biochim Biophys Acta Mol Basis Dis. 2019;1865:107-114 pubmed publisher
Schoonover K, Queern S, Lapi S, Roberts R. Impaired copper transport in schizophrenia results in a copper-deficient brain state: A new side to the dysbindin story. World J Biol Psychiatry. 2020;21:13-28 pubmed publisher
Maciel M, Hernández Barrientos D, Herrera I, Selman M, Pardo A, Cabrera S. Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. Aging (Albany NY). 2018;10:2098-2112 pubmed publisher
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Ahn C, Choi J, Jeung E. Organ‑specific expression of the divalent ion channel proteins NCKX3, TRPV2, CTR1, ATP7A, IREG1 and HEPH in various canine organs. Mol Med Rep. 2018;18:1773-1781 pubmed publisher
Buß I, Hamacher A, Sarin N, Kassack M, Kalayda G. Relevance of copper transporter 1 and organic cation transporters 1-3 for oxaliplatin uptake and drug resistance in colorectal cancer cells. Metallomics. 2018;10:414-425 pubmed publisher
Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, et al. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Mol Neurodegener. 2018;13:4 pubmed publisher
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Verma S, Pillay P, Naicker T, Moodley J, Mackraj I. Placental hypoxia inducible factor -1? & CHOP immuno-histochemical expression relative to maternal circulatory syncytiotrophoblast micro-vesicles in preeclamptic and normotensive pregnancies. Eur J Obstet Gynecol Reprod Biol. 2018;220:18-24 pubmed publisher
Jain A, ZODE G, Kasetti R, Ran F, Yan W, Sharma T, et al. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proc Natl Acad Sci U S A. 2017;114:11199-11204 pubmed publisher
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice. Sci Rep. 2017;7:8976 pubmed publisher
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Ying R, Wang X, Yang Y, Gu Z, Mai J, Qiu Q, et al. Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway. Life Sci. 2016;144:208-17 pubmed publisher
Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, Bièche I, et al. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease. Brain. 2015;138:2383-98 pubmed publisher
Sun Q, Zhong W, Zhang W, Li Q, Sun X, Tan X, et al. Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways. Am J Physiol Gastrointest Liver Physiol. 2015;308:G757-66 pubmed publisher
Lee Y, Hah Y, Ha Y, Kang Y, Kang K, Hwang J, et al. The autophagy-related marker LC3 can predict prognosis in human hepatocellular carcinoma. PLoS ONE. 2013;8:e81540 pubmed publisher
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product information
master code :
NB100-402
SKU :
NB100-402
product name :
SLC31A1/CTR1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The SLC31A1/CTR1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SLC31A1/CTR1. This antibody reacts with canine,human,mouse,porcine,rat,xenopus,zebrafish. The SLC31A1/CTR1 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry.
target :
SLC31A1/CTR1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [Uniprot: O15431]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Canine,Human,Mouse,Porcine,Rat,Xenopus,Zebrafish
gene symbol :
SLC31A1
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry
USD :
399 USD
alt names :
Copper transporter 1, COPT1high affinity copper uptake protein 1, CTR1MGC75487, hCTR1copper transport 1 homolog, solute carrier family 31 (copper transporters), member 1, Solute carrier family 31 member 1
storage :
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.