product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MDC1 Antibody - BSA Free
catalog :
NB100-395
quantity :
100 ul
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Novus Biologicals product webpage
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; fig 5
Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher
Wang Y, Liu X, Zuo X, Wang C, Zhang Z, Zhang H, et al. NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors. Cell Genom. 2024;4:100550 pubmed publisher
Heyza J, Mikhova M, Bahl A, Broadbent D, Schmidt J. Systematic analysis of the molecular and biophysical properties of key DNA damage response factors. elife. 2023;12: pubmed publisher
Schleicher E, Dhoonmoon A, Jackson L, Khatib J, Nicolae C, Moldovan G. The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells. Oncogenesis. 2022;11:33 pubmed publisher
Walter L, Canup B, Pujada A, Bui T, Arbasi B, Laroui H, et al. Matrix metalloproteinase 9 (MMP9) limits reactive oxygen species (ROS) accumulation and DNA damage in colitis-associated cancer. Cell Death Dis. 2020;11:767 pubmed publisher
Chen T, Arra M, Mbalaviele G, Swarnkar G, Abu Amer Y. Inflammatory Responses Reprogram TREGS Through Impairment of Neuropilin-1. Sci Rep. 2019;9:10429 pubmed publisher
Ohta Y, Nomura E, Shang J, Feng T, Huang Y, Liu X, et al. Enhanced oxidative stress and the treatment by edaravone in mice model of amyotrophic lateral sclerosis. J Neurosci Res. 2019;97:607-619 pubmed publisher
Serebryannyy L, Misteli T. HiPLA: High-throughput imaging proximity ligation assay. Methods. 2019;157:80-87 pubmed publisher
Singh R, Hillestad M, Livia C, Li M, Alekseev A, Witt T, et al. M3RNA Drives Targeted Gene Delivery in Acute Myocardial Infarction. Tissue Eng Part A. 2018;: pubmed publisher
Henrich M, Geibl F, Lee B, Chiu W, Koprich J, Brotchie J, et al. A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia. Acta Neuropathol Commun. 2018;6:39 pubmed publisher
Yun Y, Oh J, Kim Y, Kim G, Lee M, Ha Y. Characterization of neural stem cells modified with hypoxia/neuron-specific VEGF expression system for spinal cord injury. Gene Ther. 2017;: pubmed publisher
Bick G, Zhang F, Meetei A, Andreassen P. Coordination of the recruitment of the FANCD2 and PALB2 Fanconi anemia proteins by an ubiquitin signaling network. Chromosoma. 2017;126:417-430 pubmed publisher
Luengo Gil G, Calvo M, Martín Villar E, Águila S, Bohdan N, Anton A, et al. Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase. Sci Rep. 2016;6:27544 pubmed publisher
Hodge C, Ismail I, Edwards R, Hura G, Xiao A, Tainer J, et al. RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J Biol Chem. 2016;291:9396-410 pubmed publisher
Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed publisher
Vadrot N, Duband Goulet I, Cabet E, Attanda W, Barateau A, Vicart P, et al. The p.R482W substitution in A-type lamins deregulates SREBP1 activity in Dunnigan-type familial partial lipodystrophy. Hum Mol Genet. 2015;24:2096-109 pubmed publisher
product information
master code :
NB100-395
SKU :
NB100-395
product name :
MDC1 Antibody - BSA Free
unit size :
100 ul
description :
The MDC1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to MDC1. This antibody reacts with human,mouse. The MDC1 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation.
target :
MDC1
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide, which represented a portion of human Mediator of DNA Damage Checkpoint Protein 1 encoded within exon 5 (NP_055456.1).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
MDC1
accessionNumbers :
Q14676
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation
USD :
469 USD
alt names :
DKFZp781A0122, Em:AB023051.5, KIAA0170MGC166888, mediator of DNA damage checkpoint 1, mediator of DNA damage checkpoint protein 1, mediator of DNA-damage checkpoint 1, NFBD1homologue to Drosophila photoreceptor protein calphotin, Nuclear factor with BRCT domains 1
storage :
Store at 4C. Do not freeze.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.