Cyr61/CCN1 Antibody - BSA Free | Novus Biologicals NB100-356 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Cyr61/CCN1 Antibody - BSA Free

catalog :

NB100-356

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, blocking or activating experiments

more info or order :

Novus Biologicals product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; 1-10 ug/ml; loading ...; fig 5d western blot; human; loading ...; fig 5s1a	Mugahid D, Kalocsay M, Liu X, Gruver J, Peshkin L, Kirschner M. YAP regulates cell size and growth dynamics via non-cell autonomous mediators. elife. 2020;9: pubmed publisher
immunohistochemistry - paraffin section; human; 5 ug/ml; loading ...; fig 6a, 6b, 6d	Hellinger J, Hüchel S, Goetz L, Bauerschmitz G, Emons G, Gründker C. Inhibition of CYR61-S100A4 Axis Limits Breast Cancer Invasion. Front Oncol. 2019;9:1074 pubmed publisher
blocking or activating experiments; human; 1:1000; fig 5s1a	Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed publisher
	Wang Z, Kim S, Tu W, Kim J, Xu A, Yang Y, et al. Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment. Cell Metab. 2023;35:1209-1226.e13 pubmed publisher
	Holmes B, Benavides Serrato A, Saunders J, Kumar S, Nishimura R, Gera J. mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics. Neoplasia. 2021;23:951-965 pubmed publisher
	Uneda A, Kurozumi K, Fujimura A, Fujii K, Ishida J, Shimazu Y, et al. Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration. Acta Neuropathol Commun. 2021;9:29 pubmed publisher
	Choi C, Jeong W, Ghang B, Park Y, Hyun C, Cho M, et al. Cyr61 synthesis is induced by interleukin-6 and promotes migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther. 2020;22:275 pubmed publisher
	Corwin C, Nikolopoulou A, Pan A, Nunez Santos M, Vallabhajosula S, Serrano P, et al. Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets. J Neuroinflammation. 2018;15:272 pubmed publisher
	Yao L, Chen W, Song K, Han C, Gandhi C, Lim K, et al. 15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury. PLoS ONE. 2017;12:e0176106 pubmed publisher
	Mehdawi L, Satapathy S, Gustafsson A, Lundholm K, Alvarado Kristensson M, Sjölander A. A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells. Oncotarget. 2017;8:35033-35047 pubmed publisher
	Prima V, Kaliberova L, Kaliberov S, Curiel D, Kusmartsev S. COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells. Proc Natl Acad Sci U S A. 2017;114:1117-1122 pubmed publisher
	Li Y, Adur M, Kannan A, Davila J, Zhao Y, Nowak R, et al. Progesterone Alleviates Endometriosis via Inhibition of Uterine Cell Proliferation, Inflammation and Angiogenesis in an Immunocompetent Mouse Model. PLoS ONE. 2016;11:e0165347 pubmed publisher
	Mehdawi L, Prasad C, Ehrnstrom R, Andersson T, Sjölander A. Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells. Mol Oncol. 2016;10:1415-1429 pubmed publisher
	Miyagishi H, Kosuge Y, Takano A, Endo M, Nango H, Yamagata Murayama S, et al. Increased Expression of 15-Hydroxyprostaglandin Dehydrogenase in Spinal Astrocytes During Disease Progression in a Model of Amyotrophic Lateral Sclerosis. Cell Mol Neurobiol. 2017;37:445-452 pubmed publisher
	Hsiao H, Thatcher T, Colas R, Serhan C, Phipps R, Sime P. Resolvin D1 Reduces Emphysema and Chronic Inflammation. Am J Pathol. 2015;185:3189-201 pubmed publisher
	de Hair M, Leclerc P, Newsum E, Maijer K, van de Sande M, Ramwadhdoebe T, et al. Expression of Prostaglandin E2 Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients. PLoS ONE. 2015;10:e0133669 pubmed publisher

product information

master code :

NB100-356

SKU :

NB100-356

product name :

Cyr61/CCN1 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Cyr61/CCN1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Cyr61/CCN1. This antibody reacts with human,mouse,rabbit. The Cyr61/CCN1 Antibody - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Block/Neutralize,Functional Assay,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western.

target :

Cyr61/CCN1

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250). [UniProt# O00622]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Rabbit

theoretical molecular weight :

37 kDa

gene symbol :

CCN1

Antibody validation :

Biological Validation

accessionNumbers :

O00622

applications :

IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Block/Neutralize,Functional Assay,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western

USD :

409 USD

alt names :

CCN family member 1, CCN1IGF-binding protein 10, Cysteine-rich angiogenic inducer 61, cysteine-rich, angiogenic inducer, 61, GIG1cysteine-rich heparin-binding protein 61, IBP-10, IGFBP-10, IGFBP10cysteine-rich, anigogenic inducer, 61, Insulin-like growth factor-binding protein 10, protein CYR61, Protein GIG1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage