BubR1 Antibody (8G1) - BSA Free | Novus Biologicals NB100-353 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

BubR1 Antibody (8G1) - BSA Free

catalog :

NB100-353

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8G1

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Novus Biologicals product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; human	Brownlow N, Pike T, Zicha D, Collinson L, Parker P. Mitotic catenation is monitored and resolved by a PKCÎµ-regulated pathway. Nat Commun. 2014;5:5685 pubmed publisher
immunocytochemistry; human	Silio V, Redondo Muñoz J, Carrera A. Phosphoinositide 3-kinase ? regulates chromosome segregation in mitosis. Mol Biol Cell. 2012;23:4526-42 pubmed publisher
western blot; human	Deeraksa A, Pan J, Sha Y, Liu X, Eissa N, Lin S, et al. Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis. Oncogene. 2013;32:2973-83 pubmed publisher
immunocytochemistry; human	De Rycker M, Rigoreau L, Dowding S, Parker P. A high-content, cell-based screen identifies micropolyin, a new inhibitor of microtubule dynamics. Chem Biol Drug Des. 2009;73:599-610 pubmed publisher
western blot; human	Bohers E, Sarafan Vasseur N, Drouet A, Paresy M, Latouche J, Flaman J, et al. Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy. Hum Genet. 2008;124:473-8 pubmed publisher
	Kiseljak Vassiliades K, Zhang Y, Kar A, Razzaghi R, Xu M, Gowan K, et al. Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma. Endocrinology. 2018;159:2532-2544 pubmed publisher
	Martini S, Soliman T, Gobbi G, Mirandola P, Carubbi C, Masselli E, et al. PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly. Mol Cancer Res. 2018;16:3-15 pubmed publisher
	Regan Anderson T, Ma S, Raj G, Cidlowski J, Helle T, Knutson T, et al. Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer. Cancer Res. 2016;76:1653-63 pubmed publisher
	Trachana V, van Wely K, Guerrero A, Fütterer A, Martinez A C. Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability. Proc Natl Acad Sci U S A. 2007;104:2691-6 pubmed
	Chan G, Jablonski S, Sudakin V, Hittle J, Yen T. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J Cell Biol. 1999;146:941-54 pubmed

product information

master code :

NB100-353

SKU :

NB100-353

product name :

BubR1 Antibody (8G1) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The BubR1 Antibody (8G1) - BSA Free from Novus is a mouse monoclonal antibody to BubR1. This antibody reacts with human,mouse. The BubR1 Antibody (8G1) - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunoprecipitation,CyTOF-ready.

target :

BubR1

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

8G1

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

A portion of human BubR1 tagged at the N-terminus with pMAL (residues 1-350). [UniProt# O60566]

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human,Mouse

specificity :

NB100-353 is specific for hBUBR1

theoretical molecular weight :

120 kDa

gene symbol :

BUB1B

applications :

Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunoprecipitation,CyTOF-ready

USD :

409 USD

alt names :

Bub1A, BUBR1budding uninhibited by benzimidazoles 1 (yeast homolog), beta, budding uninhibited by benzimidazoles 1 homolog beta (yeast), EC 2.7.11.1, hBUBR1, MAD3/BUB1-related protein kinase, MAD3LBUB1beta, Mitotic checkpoint kinase MAD3L, Protein SSK1, SSK1mitotic checkpoint serine/threonine-protein kinase BUB1 beta

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage