FANCD2 Antibody (FI-17) | Novus Biologicals NB100-316 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

FANCD2 Antibody (FI-17)

catalog :

NB100-316

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

FI-17

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; loading ...; fig 4c	Slyskova J, Sabatella M, Ribeiro Silva C, Stok C, Theil A, Vermeulen W, et al. Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage. Nucleic Acids Res. 2018;46:9537-9549 pubmed publisher
western blot; human	Nalepa G, Enzor R, Sun Z, Marchal C, Park S, Yang Y, et al. Fanconi anemia signaling network regulates the spindle assembly checkpoint. J Clin Invest. 2013;123:3839-47 pubmed publisher
western blot; human	Kusayanagi T, Tsukuda S, Shimura S, Manita D, Iwakiri K, Kamisuki S, et al. The antitumor agent doxorubicin binds to Fanconi anemia group F protein. Bioorg Med Chem. 2012;20:6248-55 pubmed publisher
western blot; human	Park S, Beck B, Saadatzadeh M, Haneline L, Clapp D, Lee S. Fanconi anemia D2 protein is an apoptotic target mediated by caspases. J Cell Biochem. 2011;112:2383-91 pubmed publisher
immunoprecipitation; human western blot; human	Park S, Ciccone S, Beck B, Hwang B, Freie B, Clapp D, et al. Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. J Biol Chem. 2004;279:30053-9 pubmed
	Pe xf1 a G xf3 mez M, Moreno Gordillo P, Narmont x117 M, Garc xed a Calder xf3 n C, Ruk x161 x117 nait x117 A, Klima x161 auskas S, et al. FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine. Cell Death Dis. 2022;13:503 pubmed publisher
	Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, et al. Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span. FASEB J. 2020;34:5590-5609 pubmed publisher
	Sato K, Brandsma I, van Rossum Fikkert S, Verkaik N, Oostra A, Dorsman J, et al. HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair. Nucleic Acids Res. 2020;48:2442-2456 pubmed publisher
	Sabatella M, Pines A, Slyskova J, Vermeulen W, Lans H. ERCC1-XPF targeting to psoralen-DNA crosslinks depends on XPA and FANCD2. Cell Mol Life Sci. 2019;: pubmed publisher
	Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, et al. Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia. Cell Rep. 2018;25:561-570.e6 pubmed publisher
	Miyazawa H, Yamamoto M, Yamaguchi Y, Miura M. Mammalian embryos show metabolic plasticity toward the surrounding environment during neural tube closure. Genes Cells. 2018;23:794-802 pubmed publisher
	Finicle B, Ramirez M, Liu G, Selwan E, McCracken A, Yu J, et al. Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6. J Cell Sci. 2018;131: pubmed publisher
	Kim S, Roy S, Chen B, Nguyen T, McMonigle R, McCracken A, et al. Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways. J Clin Invest. 2016;126:4088-4102 pubmed publisher
	Joyal J, Sun Y, Gantner M, Shao Z, Evans L, Saba N, et al. Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nat Med. 2016;22:439-45 pubmed publisher
	Ulrich F, Carretero Ortega J, Menendez J, Narvaez C, Sun B, Lancaster E, et al. Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development. 2016;143:147-59 pubmed publisher
	Lin A, Abbas S, Kim S, Ortega M, Bouamar H, Escobedo Y, et al. D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. Nat Commun. 2015;6:7768 pubmed publisher
	Vanhollebeke B, Stone O, Bostaille N, Cho C, Zhou Y, Maquet E, et al. Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. elife. 2015;4: pubmed publisher
	Bhagwat N, Olsen A, Wang A, Hanada K, Stuckert P, Kanaar R, et al. XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Mol Cell Biol. 2009;29:6427-37 pubmed publisher
	Chu P, Wang T, Lu Y, Chou C, Yang Y, Chang M. Involvement of p29 in DNA damage responses and Fanconi anemia pathway. Carcinogenesis. 2009;30:1710-6 pubmed publisher
	Willers H, Taghian A, Luo C, Treszezamsky A, Sgroi D, Powell S. Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies. Mol Cancer Res. 2009;7:1304-9 pubmed publisher
	Si Y, Pulliam A, Linka Y, Ciccone S, Leurs C, Yuan J, et al. Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells. Blood. 2008;112:4458-65 pubmed publisher
	Tremblay C, Huang F, Habi O, Huard C, Godin C, Levesque G, et al. HES1 is a novel interactor of the Fanconi anemia core complex. Blood. 2008;112:2062-70 pubmed publisher
	Nomura Y, Adachi N, Koyama H. Human Mus81 and FANCB independently contribute to repair of DNA damage during replication. Genes Cells. 2007;12:1111-22 pubmed

product information

master code :

NB100-316

SKU :

NB100-316

product name :

FANCD2 Antibody (FI-17)

unit size :

0.1 ml (also 0.025 ml)

description :

The FANCD2 Antibody (FI-17) - BSA Free from Novus is a mouse monoclonal antibody to FANCD2. This antibody reacts with hamster (negative),human,mouse,mouse (negative). The FANCD2 Antibody (FI-17) - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,Chromatin Immunoprecipitation (ChIP).

target :

FANCD2

category :

Primary Antibodies

buffer :

Ascites

clonality :

Monoclonal

clone :

FI-17

conjugate :

Unconjugated

host :

Mouse

immunogen :

This FANCD2 Antibody (FI-17) was developed against human FANCD2 fusion protein [Swiss-Prot: Q9BXW9]

isotype :

IgG1

purity :

Unpurified

species :

Hamster (Negative),Human,Mouse,Mouse (Negative)

theoretical molecular weight :

164.1 kDa

gene symbol :

FANCD2

accessionNumbers :

Q9BXW9

applications :

Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,Chromatin Immunoprecipitation (ChIP)

USD :

409 USD

alt names :

DKFZp762A223, FA4, FACD, FAD, FAD2, FA-D2, FADFAD2, FANCD, Fanconi anemia complementation group D2, Fanconi anemia group D2 protein, Fanconi anemia, complementation group D2, FLJ23826, FPN1, HFE4, IREG1, Protein FACD2, SLC11A3

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage