TERT Antibody (2D8) | Novus Biologicals NB100-297 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TERT Antibody (2D8)

catalog :

NB100-297

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D8

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; human	Akiyama M, Ozaki K, Kawano T, Yamada O, Kawauchi K, Ida H, et al. Telomerase activation as a repair response to radiation-induced DNA damage in Y79 retinoblastoma cells. Cancer Lett. 2013;340:82-7 pubmed publisher
western blot; human	Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, et al. EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. Cancer Sci. 2011;102:351-60 pubmed publisher
immunohistochemistry - frozen section; human	Fabricius E, Kruse Boitschenko U, Khoury R, Wildner G, Raguse J, Klein M, et al. Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues. Int J Oncol. 2009;35:1377-94 pubmed
immunohistochemistry; human	Fabricius E, Kruse Boitschenko U, Khoury R, Wildner G, Raguse J, Klein M. Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues. Int J Oncol. 2009;34:1257-79 pubmed
flow cytometry; human immunocytochemistry; human	Zhang J, Eguchi J, Kruse C, Gomez G, Fakhrai H, Schroter S, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-575 pubmed publisher
western blot; human	Deissler H, Deissler H, Lang G, Lang G. Generation and characterization of iBREC: novel hTERT-immortalized bovine retinal endothelial cells. Int J Mol Med. 2005;16:65-70 pubmed
western blot; human	Masutomi K, Possemato R, Wong J, Currier J, Tothova Z, Manola J, et al. The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A. 2005;102:8222-7 pubmed
	Yang J, Wu R, Li W, Gao L, Yang Y, Li P, et al. The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells. Mol Carcinog. 2018;57:512-521 pubmed publisher
	Xiao Y, Gao X, Gannot G, Emmert Buck M, Srivastava S, Wagner P, et al. Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection. Int J Cancer. 2008;122:2178-86 pubmed publisher
	Blasco M, Hahn W. Evolving views of telomerase and cancer. Trends Cell Biol. 2003;13:289-94 pubmed

product information

master code :

NB100-297

SKU :

NB100-297

product name :

TERT Antibody (2D8)

unit size :

0.1 ml (also 0.025 ml)

description :

The TERT Antibody (2D8) - BSA Free from Novus is a mouse monoclonal antibody to TERT. This antibody reacts with human. The TERT Antibody (2D8) - BSA Free has been validated for the following applications: IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated.

target :

TERT

category :

Primary Antibodies

buffer :

Ascites

clonality :

Monoclonal

clone :

2D8

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full-length recombinant human Telomerase reverse transcriptase from insect cells. [UniProt# O14746]

isotype :

IgM

purity :

Unpurified

species :

Human

theoretical molecular weight :

127 kDa

gene symbol :

TERT

accessionNumbers :

O14746

applications :

IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated

USD :

409 USD

alt names :

EST2Telomerase-associated protein 2, hEST2, hTERT, TCS1EC 2.7.7.49, Telomerase catalytic subunit, telomerase reverse transcriptase, TP2HEST2, TRTEC 2.7.7

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage