product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
HIF-1 alpha Antibody (HA111) - BSA Free
catalog :
NB100-296
quantity :
0.1 ml (also 0.025 ml)
price :
339 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HA111
reactivity :
human, mouse, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human
Rajakumar A, Michael H, Daftary A, Jeyabalan A, Gilmour C, Conrad K. Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. Placenta. 2008;29:290-9 pubmed publisher
  • immunoprecipitation; domestic rabbit
  • western blot; domestic rabbit
Zheng X, Ruas J, Cao R, Salomons F, Cao Y, Poellinger L, et al. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Mol Cell Biol. 2006;26:4628-41 pubmed
Iorio J, Lastraioli E, Tofani L, Petroni G, Antonuzzo L, Messerini L, et al. hERG1 and HIF-2α Behave as Biomarkers of Positive Response to Bevacizumab in Metastatic Colorectal Cancer Patients. Transl Oncol. 2020;13:100740 pubmed publisher
Lee K, Spata M, Maduka R, Vonderheide R, Simon M. Hif1? Deletion Limits Tissue Regeneration via Aberrant B Cell Accumulation in Experimental Pancreatitis. Cell Rep. 2018;23:3457-3464 pubmed publisher
Li F, Lee K, Simon M. Detection of Hypoxia and HIF in Paraffin-Embedded Tumor Tissues. Methods Mol Biol. 2018;1742:277-282 pubmed publisher
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice. Sci Rep. 2017;7:8976 pubmed publisher
Lee K, Spata M, Bayne L, Buza E, Durham A, Allman D, et al. Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia. Cancer Discov. 2016;6:256-69 pubmed publisher
Zhong W, Li Q, Sun Q, Zhang W, Zhang J, Sun X, et al. Preventing Gut Leakiness and Endotoxemia Contributes to the Protective Effect of Zinc on Alcohol-Induced Steatohepatitis in Rats. J Nutr. 2015;145:2690-8 pubmed publisher
Bonner C, Kerr Conte J, Gmyr V, Queniat G, Moerman E, Thévenet J, et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat Med. 2015;21:512-7 pubmed publisher
Lauzier M, Robitaille G, Chan D, Giaccia A, Richard D. (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors. Mol Pharmacol. 2008;74:282-8 pubmed publisher
Gillespie D, Whang K, Ragel B, Flynn J, Kelly D, Jensen R. Silencing of hypoxia inducible factor-1alpha by RNA interference attenuates human glioma cell growth in vivo. Clin Cancer Res. 2007;13:2441-8 pubmed
Jensen R, Ragel B, Whang K, Gillespie D. Inhibition of hypoxia inducible factor-1alpha (HIF-1alpha) decreases vascular endothelial growth factor (VEGF) secretion and tumor growth in malignant gliomas. J Neurooncol. 2006;78:233-47 pubmed
product information
master code :
NB100-296
SKU :
NB100-296
product name :
HIF-1 alpha Antibody (HA111) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The HIF-1 alpha Antibody (HA111) - BSA Free from Novus is a mouse monoclonal antibody to HIF-1 alpha. This antibody reacts with human,mouse,rabbit. The HIF-1 alpha Antibody (HA111) - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry.
target :
HIF-1 alpha
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
HA111
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This HIF-1 alpha Antibody (HA111) was developed against Human HIF-1 alpha, corresponding to amino acids 329 - 530 [Uniprot# Q16665].
isotype :
IgG2 Alpha
purity :
Protein G purified
species :
Human,Mouse,Rabbit
theoretical molecular weight :
93 kDa
gene symbol :
HIF1A
applications :
IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry
USD :
339 USD
alt names :
AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF1, HIF-1 alpha, HIF1A, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.