DNMT1 Antibody | Novus Biologicals NB100-264 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DNMT1 Antibody

catalog :

NB100-264

quantity :

0.1 ml

price :

333 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

5B10

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 10

Reference
Liu N, Zhang X, Jiang S, Shi J, Cui J, Liu X, et al. Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning. Neural Regen Res. 2020;15:2362-2368 pubmed publisher
Raja G, Lite C, Subhashree K, Santosh W, Barathi S. Prenatal bisphenol-A exposure altered exploratory and anxiety-like behaviour and induced non-monotonic, sex-specific changes in the cortical expression of CYP19A1, BDNF and intracellular signaling proteins in F1 rats. Food Chem Toxicol. 2020;142:111442 pubmed publisher
Chen Z, Zheng J, Hong H, Chen D, Deng L, Zhang X, et al. lncRNA HOTAIRM1 promotes osteogenesis of hDFSCs by epigenetically regulating HOXA2 via DNMT1 in vitro. J Cell Physiol. 2020;: pubmed publisher
Liberti D, Zepp J, Bartoni C, Liberti K, Zhou S, Lu M, et al. Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate. Dev Biol. 2019;454:108-117 pubmed publisher
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018;15:909-912 pubmed publisher
Gustafsson J, Katsioudi G, Degn M, Ejlerskov P, Issazadeh Navikas S, Kornum B. DNMT1 regulates expression of MHC class I in post-mitotic neurons. Mol Brain. 2018;11:36 pubmed publisher
Gu H, Gao J, Guo W, Zhou Y, Kong Q. The expression of DNA methyltransferases3A is specifically downregulated in chorionic villi of early embryo growth arrest cases. Mol Med Rep. 2017;16:591-596 pubmed publisher
Chang C, Pirozzi G, Wen S, Chung I, Chiu B, Errico S, et al. Multiple structural and epigenetic defects in the human leukocyte antigen class I antigen presentation pathway in a recurrent metastatic melanoma following immunotherapy. J Biol Chem. 2015;290:26562-75 pubmed publisher
VispÃ© S, Deroide A, Davoine E, Desjobert C, Lestienne F, Fournier L, et al. Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells. Oncotarget. 2015;6:15265-82 pubmed
Cui Y, Irudayaraj J. Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy. Nucleic Acids Res. 2015;43:3046-55 pubmed publisher

product information

brand :

Novus

SKU :

NB100-264

product name :

DNMT1 Antibody

unit sizes :

0.1 ml

description :

The DNMT1 Antibody from Novus is a rabbit polyclonal antibody to DNMT1. This antibody reacts with human, mouse. The DNMT1 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Knockout Validated, Knockdown Validated.

target :

DNMT1

category :

Primary Antibodies

buffer :

Whole antisera

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Contained within amino acids 1-125 of the N-terminus of human Dnmt1. [UniProt# P26358]

isotype :

IgG

purity :

Unpurified

species :

Human, Mouse

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

uses :

In Western blot a band can be seen at ~190 kDa. NOTE: This antibody does not neutralize the enzymatic activity of its corresponding methyltransferase. In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.

theoretical molecular weight :

190 kDa

gene symbol :

DNMT1

catalog number base :

NB100-264

accessionNumbers :

P26358

applications :

Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Knockout Validated, Knockdown Validated

USD :

333 USD

default size :

TRUE

alt names :

AIM, CXXC9CXXC finger protein 9, CXXC-type zinc finger protein 9, DNA (cytosine-5-)-methyltransferase 1, DNA (cytosine-5)-methyltransferase 1, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA MTase HsaI, DNMT, Dnmt1, EC 2.1.1.37, FLJ16293, m.HsaI, MCMTMGC104992