product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
HRD1 Antibody - BSA Free
catalog :
NB100-2526
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Ubi-1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 34
Reference
Poliquin S, Nwosu G, Randhave K, Shen W, Flamm C, Kang J. Modulating Endoplasmic Reticulum Chaperones and Mutant Protein Degradation in GABRG2(Q390X) Associated with Genetic Epilepsy with Febrile Seizures Plus and Dravet Syndrome. Int J Mol Sci. 2024;25: pubmed publisher
Lee E, Aryal Y, Kim T, Pokharel E, Kim J, Yamamoto H, et al. The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development. Front Physiol. 2022;13:1079355 pubmed publisher
Lee E, Aryal Y, Kim T, Kim J, Yamamoto H, An C, et al. Facilitation of Reparative Dentin Using a Drug Repositioning Approach With 4-Phenylbutric Acid. Front Physiol. 2022;13:885593 pubmed publisher
Binder P, Nguyen B, Collins L, Zi M, Liu W, Christou F, et al. Pak2 Regulation of Nrf2 Serves as a Novel Signaling Nexus Linking ER Stress Response and Oxidative Stress in the Heart. Front Cardiovasc Med. 2022;9:851419 pubmed publisher
Seidel E, Dassa L, Kahlon S, Tirosh B, Halenius A, Seidel Malkinson T, et al. A slowly cleaved viral signal peptide acts as a protein-integral immune evasion domain. Nat Commun. 2021;12:2061 pubmed publisher
Thurner L, Hartmann S, Bewarder M, Fadle N, Regitz E, Schormann C, et al. Identification of the atypically modified autoantigen Ars2 as the target of B-cell receptors from activated B cell-type diffuse large B-cell lymphoma. Haematologica. 2020;: pubmed publisher
Yoon Y, Lee J, Song K, Noh H, Lee S. Melatonin-stimulated exosomes enhance the regenerative potential of chronic kidney disease-derived mesenchymal stem/stromal cells via cellular prion proteins. J Pineal Res. 2020;68:e12632 pubmed publisher
Schwertheim S, Theurer S, Jastrow H, Herold T, Ting S, Westerwick D, et al. New insights into intranuclear inclusions in thyroid carcinoma: Association with autophagy and with BRAFV600E mutation. PLoS ONE. 2019;14:e0226199 pubmed publisher
Sn S, Pandurangi J, Murumalla R, Dj V, Garimella L, Acharya A, et al. Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration. EBioMedicine. 2019;50:260-273 pubmed publisher
Swatek K, Usher J, Kueck A, Gladkova C, Mevissen T, Pruneda J, et al. Insights into ubiquitin chain architecture using Ub-clipping. Nature. 2019;572:533-537 pubmed publisher
Jiang L, Zhu B, Zhao Y, Li X, Liu T, Piña Crespo J, et al. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. J Clin Invest. 2019;130: pubmed publisher
Aalto A, Mohan A, Schwintzer L, Kupka S, Kietz C, Walczak H, et al. M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila. Cell Death Differ. 2019;26:860-876 pubmed publisher
Gladkova C, Maslen S, Skehel J, Komander D. Mechanism of parkin activation by PINK1. Nature. 2018;559:410-414 pubmed publisher
Xie H, Tang C, Song J, Mancuso A, Del Valle J, Cao J, et al. IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. J Clin Invest. 2018;128:1300-1316 pubmed publisher
Gogoi M, Ravikumar V, Dixit N, Chakravortty D. Salmonella escapes antigen presentation through K63 ubiquitination mediated endosomal proteolysis of MHC II via modulation of endosomal acidification in dendritic cells. Pathog Dis. 2018;76: pubmed publisher
Deger S, Hung A, Gamboa J, Siew E, Ellis C, Booker C, et al. Systemic inflammation is associated with exaggerated skeletal muscle protein catabolism in maintenance hemodialysis patients. JCI Insight. 2017;2: pubmed publisher
Gersch M, Gladkova C, Schubert A, Michel M, Maslen S, Komander D. Mechanism and regulation of the Lys6-selective deubiquitinase USP30. Nat Struct Mol Biol. 2017;24:920-930 pubmed publisher
Michel M, Swatek K, Hospenthal M, Komander D. Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling. Mol Cell. 2017;68:233-246.e5 pubmed publisher
Kaul Z, Chakrabarti O. Tumor susceptibility gene 101 regulates predisposition to apoptosis via ESCRT machinery accessory proteins. Mol Biol Cell. 2017;28:2106-2122 pubmed publisher
Hwang J, Walczak C, Shaler T, Olzmann J, Zhang L, Elias J, et al. Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1. J Biol Chem. 2017;292:9104-9116 pubmed publisher
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher
Pruneda J, Durkin C, Geurink P, Ovaa H, Santhanam B, Holden D, et al. The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases. Mol Cell. 2016;63:261-276 pubmed publisher
Schwab A, Ebert A. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports. 2015;5:1039-1052 pubmed publisher
Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed publisher
Begum G, Yan H, Li L, Singh A, Dixon C, Sun D. Docosahexaenoic acid reduces ER stress and abnormal protein accumulation and improves neuronal function following traumatic brain injury. J Neurosci. 2014;34:3743-55 pubmed publisher
Ejlerskov P, Rasmussen I, Nielsen T, Bergström A, Tohyama Y, Jensen P, et al. Tubulin polymerization-promoting protein (TPPP/p25?) promotes unconventional secretion of ?-synuclein through exophagy by impairing autophagosome-lysosome fusion. J Biol Chem. 2013;288:17313-35 pubmed publisher
Maroui M, Kheddache Atmane S, El Asmi F, Dianoux L, Aubry M, Chelbi Alix M. Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms. PLoS ONE. 2012;7:e44949 pubmed publisher
Rosenfeldt M, Nixon C, Liu E, Mah L, Ryan K. Analysis of macroautophagy by immunohistochemistry. Autophagy. 2012;8:963-9 pubmed publisher
Stuttmann J, Lechner E, Guerois R, Parker J, Nussaume L, Genschik P, et al. COP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis. J Biol Chem. 2009;284:7920-30 pubmed publisher
Dayal S, Sparks A, Jacob J, Allende Vega N, Lane D, Saville M. Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53. J Biol Chem. 2009;284:5030-41 pubmed publisher
Watson M, Lagow R, Xu K, Zhang B, Bonini N. A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1. J Biol Chem. 2008;283:24972-81 pubmed publisher
Chang L, Kamata H, Solinas G, Luo J, Maeda S, Venuprasad K, et al. The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell. 2006;124:601-13 pubmed
Cripps D, Thomas S, Jeng Y, Yang F, Davies P, Yang A. Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation. J Biol Chem. 2006;281:10825-38 pubmed
Lichtenfels R, Kellner R, Atkins D, Bukur J, Ackermann A, Beck J, et al. Identification of metabolic enzymes in renal cell carcinoma utilizing PROTEOMEX analyses. Biochim Biophys Acta. 2003;1646:21-31 pubmed
product information
master code :
NB100-2526
SKU :
NB100-2526
product name :
HRD1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The HRD1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to HRD1. This antibody reacts with hamster,human,mouse. The HRD1 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Knockout Validated,Immunocytochemistry/ Immunofluorescence.
target :
HRD1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of human HRD1 (within residues 300-400). [UniProt Q96PK3]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Hamster,Human,Mouse
gene symbol :
SYVN1
accessionNumbers :
Q86TM6
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
E3 ubiquitin-protein ligase synoviolin, EC 6.3.2, HRD1EC 6.3.2.-, KIAA1810Synovial apoptosis inhibitor 1, MGC40372, synovial apoptosis inhibitor 1, synoviolin
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.